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Glycation in the cardiomyocyte
Glycation is a protein post-translational modification that can occur on lysine and arginine residues as a result of a non-enzymatic process known as the Maillard reaction. This modification is irreversible, so the only way it can be removed is by protein degradation and replacement.Christine E, Delligatti +1 more
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Isolation and Differentiation of Human Cardiomyocyte Progenitor Cells into Cardiomyocytes
2012To date, there is no suitable in vitro model to study human adult cardiac cell biology. Here, we describe a method for efficient isolation and expansion of human cardiomyocyte progenitor cells (CMPCs) from cardiac surgical waste or, alternatively, from fetal heart tissue.
Anke M, Smits +2 more
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Microtopographical assembly of cardiomyocytes
Integrative Biology, 2011One of the central challenges in cardiac tissue engineering is the control of the assembly and organization of functional cardiac tissue. Maintenance of a three-dimensional tissue architecture is key to myocardial function in vivo, and a variety of studies hint that provision of topological cues within scaffolds can facilitate the engineering of ...
Anuj A, Patel +2 more
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Pathophysiology of Cardiomyocytesa
Annals of the New York Academy of Sciences, 1988Isolated cardiomyocytes lend themselves very well to the quantification of pathological damage and to the determination of reversible versus irreversible changes. These single cells were used to study the cellular response to a variety of pathologic stimuli that impair structure and function.
M, Borgers +2 more
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Cryopreservation of Neonatal Cardiomyocytes
2015Cardiomyocytes are frequently used for in vitro models for cardiac research. The isolation of cells is time-consuming and, due to the cells limited proliferative abilities, must be performed frequently. To reduce the time requirements and the impact on research animals, we describe a method for cryopreserving neonatal rat cardiomyocytes (NRCMs), and ...
Adam C, Vandergriff +2 more
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The genetics of cardiomyocyte polyploidy
The regulation of ploidy in cardiomyocytes is a complex and tightly regulated aspect of cardiac development and function. Cardiomyocyte ploidy can range from diploid (2N) to 8N or even 16N, and these states change during key stages of development and disease progression.Tyler, Buddell +2 more
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Tissue factor and cardiomyocytes
Thrombosis Research, 2012Tissue factor, the initiator of blood coagulation, plays a major role in the protection of several organs against bleeding. Cardiomyocytes and fibroblasts constitutively express tissue factor. Besides its role for maintain cardiac hemostasis TF has been suggested to have several other important functions in the cardiac muscle.
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USP25 Ameliorates Pathological Cardiac Hypertrophy by Stabilizing SERCA2a in Cardiomyocytes
Circulation Research, 2023Guang Liang, Bozhi Ye, Weijian Huang
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Beyond cardiomyocytes: Cellular diversity in the heart's response to exercise
Journal of Sport and Health Science, 2023Anthony Rosenzweig +2 more
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