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The cell biology of ferroptosis
Nature Reviews Molecular Cell BiologyJames A Olzmann, Scott J Dixon
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Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell BiologySebastian Doll +2 more
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Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries
Ferroptosis is involved in various tissue injuries including neurodegeneration, ischemia-reperfusion injury, and acute liver injury. Ferroptosis inhibitors exhibit promising clinical potential in the treatment of various diseases.
Wentao Duan +11 more
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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis [PDF]
Ferroptosis is a form of regulated cell death that is caused by the iron-dependent peroxidation of lipids1,2. The glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid hydroperoxides into non-
Kirill Bersuker +2 more
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Ferroptosis in cancer (Review)
Ferroptosis is a type of programmed cell death depending on iron and reactive oxygen species. This unique cell death process has attracted a great deal of attention in the field of cancer research over the past decade. Research on the association of ferroptosis signal pathways and cancer development indicated that targeting ferroptosis has great ...
Liyi Zeng +4 more
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Iron is an essential micronutrient for microorganisms, plants, animals, and humans. However, iron overload can damage the organism through a variety of mechanisms, including the induction of cell death. Ferroptosis is defined as an iron-dependent form of regulated cell death caused by unrestricted lipid peroxidation and subsequent membrane damage ...
Daolin, Tang, Guido, Kroemer
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