Results 11 to 20 of about 138,617 (359)
Cell Reports, 2023 Summary: Solid tumors have developed robust ferroptosis resistance. The mechanism underlying ferroptosis resistance regulation in solid tumors, however, remains elusive.
Zhou Yang +11 more
doaj +1 more source
Ferroptosis-based drug delivery system as a new therapeutic opportunity for brain tumors
Frontiers in Oncology, 2023 The brain tumor is a kind of malignant tumor with brutal treatment, high recurrence rate, and poor prognosis, and the incidence and death rate is increasing yearly.
Yansheng Yao +7 more
doaj +1 more source
Exosomes and ferroptosis: roles in tumour regulation and new cancer therapies [PDF]
PeerJ, 2022 Research on the biological role of exosomes is rapidly developing, and recent evidence suggests that exosomal effects involve ferroptosis. Exosomes derived from different tissues inhibit ferroptosis, which increases tumour cell chemoresistance. Therefore,
Yixin Shi +7 more
doaj +2 more sources
Circular RNAs in ferroptosis: regulation mechanism and potential clinical application in disease
Frontiers in Pharmacology, 2023 Ferroptosis, an iron-dependent non-apoptotic form of cell death, is reportedly involved in the pathogenesis of various diseases, particularly tumors, organ injury, and degenerative pathologies.
Fei Li, Pei-Feng Li, Xiao-Dan Hao
doaj +1 more source
Lipid Metabolism and Ferroptosis [PDF]
Biology, 2021 Ferroptosis is a type of iron-dependent regulated necrosis induced by lipid peroxidation that occurs in cellular membranes. Among the various lipids, polyunsaturated fatty acids (PUFAs) associated with several phospholipids, such as phosphatidylethanolamine (PE) and phosphatidylcholine (PC), are responsible for ferroptosis-inducing lipid peroxidation ...
Ji-Yoon Lee +4 more
openaire +3 more sources
Life, 2023 Quercetin is a flavonoid present in apples, onions, tea, red wines, and berries, and it has shown different beneficial effects, such as providing cardiovascular protection, possessing anti-inflammatory properties, and demonstrating anticancer activity, among others.
Alfredo Cruz-Gregorio +1 more
openaire +3 more sources
Cross Talk Between Ferroptosis and Cerebral Ischemia
Frontiers in Neuroscience, 2020 Recently, ferroptosis has been revealed as a new form of regulated cell death. Distinct from apoptosis and necrosis, ferroptosis is evoked by iron-dependent lipid peroxidation.
Xu She, Bin Lan, Haomei Tian, Biao Tang
doaj +1 more source
Cell, 2020 Ferroptosis is a regulated form of cell death that occurs when phospholipids with polyunsaturated fatty acyl tails are oxidized in an iron-dependent manner. Research in recent years has uncovered complex cellular networks that induce and suppress lethal lipid peroxidation.
Hadian, K., Stockwell, B.R.
openaire +3 more sources
Induction and application of ferroptosis in cancer therapy
Cancer Cell International, 2022 At present, more than one cell death pathways have been found, one of which is ferroptosis. Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid peroxidation-driven regulated cell death pathway.
Qing Nie +4 more
doaj +1 more source
Ferroptosis assassinates tumor
Journal of Nanobiotechnology, 2022 AbstractIn 2020, nearly 20 million peoples got cancer and nearly 10 million peoples died of cancer, indicating the cancer remains a great threat to human health and life. New therapies are still in urgent demand. We here develop a novel cancer therapy named Ferroptosis ASsassinates Tumor (FAST) by combining iron oxide nanoparticles with cancer ...
Tao Luo, Yile Wang, Jinke Wang
openaire +3 more sources