Results 21 to 30 of about 119,861 (259)
Scientific Reports, 2022 Ferroptosis genes have recently been reported to be involved in regulating the development of cancer, but their potential role in breast cancer (BRCA) is not fully understood.
Lianli Yin, Yinghua Tang
doaj +1 more source
Induction and application of ferroptosis in cancer therapy
Cancer Cell International, 2022 At present, more than one cell death pathways have been found, one of which is ferroptosis. Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid peroxidation-driven regulated cell death pathway.
Qing Nie +4 more
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Ferroptosis-related DEGs in STS.
, 2022 Ferroptosis-related DEGs in STS.
Yi Zhao (14034) +4 more
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Ferroptosis in Haematological Malignancies and Associated Therapeutic Nanotechnologies [PDF]
, 2023 Haematological malignancies are heterogeneous groups of cancers of the bone marrow, blood or lymph nodes, and while therapeutic advances have greatly improved the lifespan and quality of life of those afflicted, many of these cancers remain incurable ...
Best, Oliver G +7 more
core +1 more source
Role of ferroptosis on tumor progression and immunotherapy
Cell Death Discovery, 2022 Ferroptosis is triggered by intracellular iron leading to accumulation of lipid peroxidation consequent promotion of cell death. Cancer cell exhibits ability to evade ferroptosis by activation of antioxidant signaling pathways such as SLC7A11/GPX4 axis ...
Deting Gong +4 more
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The Mechanism of Ferroptosis and Applications in Tumor Treatment
Frontiers in Pharmacology, 2020 Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic of the ...
Xinyue Lin +4 more
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Opportunities and challenges related to ferroptosis in glioma and neuroblastoma
Frontiers in Oncology, 2023 A newly identified form of cell death known as ferroptosis is characterized by the peroxidation of lipids in response to iron. Rapid progress in research on ferroptosis in glioma and neuroblastoma has promoted the exploitation of ferroptosis in related ...
Huizhong Chi +13 more
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NFE2L1-mediated proteasome function protects from ferroptosis
Molecular Metabolism, 2022 Objective: Ferroptosis continues to emerge as a novel modality of cell death with important therapeutic implications for a variety of diseases, most notably cancer and degenerative diseases.
Stefan Kotschi +6 more
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The diversified role of mitochondria in ferroptosis in cancer
Cell Death and Disease, 2023 Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation, and it has been studied extensively since its discovery in 2012.
Yu’e Liu +5 more
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Ferroptosis Patterns and Tumor Microenvironment Infiltration Characterization in Bladder Cancer
Frontiers in Cell and Developmental Biology, 2022 Background: Ferroptosis is a unique iron-dependent form of cell death and bladder cancer (BCa) is one of the top ten most common cancer types in the world.
Qi-Dong Xia +8 more
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