Results 111 to 120 of about 305,984 (384)
Non-familial cardiomyopathies in Lebanon: exome sequencing results for five idiopathic cases
BMC Medical Genomics, 2019 Background Cardiomyopathies affect more than 0.5% of the general population. They are associated with high risk of sudden cardiac death, which can result from either heart failure or electrical abnormalities.
Marwan M. Refaat +14 more
doaj +1 more source
Calcium and Reactive Oxygen Species Signaling Interplays in Cardiac Physiology and Pathologies
Antioxidants, 2023 Mitochondria are key players in energy production, critical activity for the smooth functioning of energy-demanding organs such as the muscles, brain, and heart.
Bianca De Nicolo +3 more
doaj +1 more source
The Feline Cardiomyopathies: 3. Cardiomyopathies other than HCM
Journal of feline medicine and surgery, 2021 Practical relevance: Although feline hypertrophic cardiomyopathy (HCM) occurs more commonly, dilated cardiomyopathy (DCM), restrictive cardiomyopathy (RCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), left ventricular noncompaction (LVNC) and
M. Kittleson, E. Côté
semanticscholar +1 more source
Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy [PDF]
, 2017 Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals ...
Braunwald +24 more
core +2 more sources
Advanced Science, EarlyView.Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu +13 more
wiley +1 more source
cMRI-BED: A novel informatics framework for cardiac MRI biomarker extraction and discovery applied to pediatric cardiomyopathy classification [PDF]
, 2015 Background\ud Pediatric cardiomyopathies are a rare, yet heterogeneous group of pathologies of the myocardium that are routinely examined clinically using Cardiovascular Magnetic Resonance Imaging (cMRI).
Prahlad G Menon +2 more
core +3 more sources
Advanced Science, EarlyView.The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
wiley +1 more source
Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts
Advanced Science, EarlyView.Cellular senescence contributes to disease burden in cardiovascular disease (CVD) and aging, highlighting the need to understand its induction. In primary cardiac fibroblasts, reduced strain and increased frequency, mimicking CVD, elicit a distinct senescent phenotype compared to oxidative stress.
Stephanie E. Schneider +5 more
wiley +1 more source
ESC Heart Failure, 2020 Several data suggest that acute myocarditis could be related to genetic variants involved in familial cardiomyopathies, particularly arrhythmogenic cardiomyopathy, but the management of patients with acute myocarditis and their families regarding their ...
N. Piriou +12 more
semanticscholar +1 more source
Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]
, 2016 A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M +4 more
core +2 more sources