Results 161 to 170 of about 305,984 (384)

Diagnostic protocol for genetic cardiomyopathies [PDF]

, 2017
Protocolos de práctica asistencial[Resumen] Características generales. Las miocardiopatías genéticas engloban un grupo heterogéneo de enfermedades. Algunas afectan de forma aislada al músculo cardíaco, en otros casos forman parte del espectro de una ...
Barge-Caballero, Gonzalo, Crespo-Leiro, María Generosa, Martínez-Paz, E.   +2 more
core   +2 more sources

A Novel Transcriptional Slippage Mechanism Rescues Dystrophin Expression from a DMD Frameshift Variant

Annals of Neurology, EarlyView.
Pathogenic DMD variants usually follow the reading‐frame rule: out‐of‐frame changes cause Duchenne muscular dystrophy, whereas in‐frame ones produce Becker muscular dystrophy (BMD). We report a 23‐year‐old man with BMD‐like weakness, calf hypertrophy, elevated creatine kinase, and dilated cardiomyopathy.
Hiroya Naruse, Jun Mitsui, Akatsuki Kubota, So Okubo, Shuichiro Mitsuchi, Kensho Sumi, Shuichi Tanifuji, Shogo Komaki, Asuka Kitamura, Meiko Maeda, Daiki Yashita, Atsushi Sudo, Takashi Matsukawa, Masashi Hamada, Wataru Satake, Shoji Tsuji, Tatsushi Toda   +16 more
wiley   +1 more source

The association of IL-1β, IL-1α, IL-6, and E-selectin with the diastolic dysfunction in patients with type 2 diabetes mellitus and preserved ejection fraction [PDF]

Vojnosanitetski Pregled
Background/Aim. The importance of chronic inflammation, endothelial dysfunction, certain cytokines, and selectins in the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) is increasingly evident and supported by evidence ...
Marinković Dejan M., Dragović Tamara, Đurić Predrag, Rakočević Jelena, Malović Dragana, Kiković Saša, Stanojević Ivan, Dejanović Bratislav, Ristić Petar, Hajduković Zoran   +9 more
doaj   +1 more source

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy [PDF]

, 2018
Diogo Mosqueira, Ingra Mannhardt, Jamie R. Bhagwan, Katarzyna Lis-Slimak, Puspita Anggraini Katili, Elizabeth Scott, Mustafa Hassan, Maksymilian Prondzynski, Stephen C. Harmer, Andrew Tinker, James G.W. Smith, Lucie Carrier, Philip M. Williams, Daniel J. Gaffney, Thomas Eschenhagen, Arne Hansen, Chris Denning   +16 more
openalex   +1 more source

Targeting the sarcomere in inherited cardiomyopathies

Nature Reviews Cardiology, 2022
Sarah J. Lehman, C. Crocini, L. Leinwand
semanticscholar   +1 more source

Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity? [PDF]

, 2017
Non-compaction of the left ventricular myocardium (LVNC) has gained increasing recognition during the last 25 years. There is a morphological trait of the myocardial structure with a spectrum from normal variants to the pathological phenotype of LVNC ...
Jenni, Rolf, Oechslin, Erwin
core  

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Tasha K. Phillips, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +16 more
wiley   +1 more source

New Developments in Magnetic Resonance Imaging of Myocardial Diseases – Technical Aspects and Clinical Applications

Journal of Interdisciplinary Medicine, 2017
Cardiac magnetic resonance imaging is an evolving imaging method that can be used in cardiovascular pathology evaluation. Technological developments have increased the clinical utility of cardiac magnetic resonance in the exploration of various cardiac ...
Morariu Mirabela, Bordi Lehel, Opincariu Diana, Ratiu Alexandra Mihaela, Condrea Sebastian, Benedek Annabell, Benedek Theodora   +6 more
doaj   +1 more source

Allopurinol reduces oxidative stress and activates Nrf2/p62 to attenuate diabetic cardiomyopathy in rats [PDF]

, 2019
Jierong Luo, Dan Yan, Sisi Li, Shiming Liu, Fei Zeng, Chi Wai Cheung, Hong Liu, Michael G. Irwin, Huansen Huang, Zhengyuan Xia   +9 more
openalex   +1 more source

Determination of selenium speciation in the muscle, kidney, and liver from different animals treated with different selenium supplements by HPLC‐ICP‐MS

Animal Research and One Health, EarlyView.
Dietary selenium (Se) deficiency is recognized as a global problem, and exogenous Se supplementation can effectively enrich its levels in animal bodies. Offal tissues are equally important as meat in Se enrichment. Varying properties among Se species require information beyond total Se concentration to fully evaluate health risk/benefits.
Xiaoqing Guo, Xueting Jia, Kai Zhang, Chaohua Tang, Xueyang Si, Bo He, Manus Carey, Lynda S. Perkins, Qingyu Zhao, Junmin Zhang   +9 more
wiley   +1 more source