Results 81 to 90 of about 296,757 (381)

Cardiomyopathies.

Acta bio-medica : Atenei Parmensis, 2019
The most common cardiomyopathies often present to primary care physicians with similar symptoms, despite the fact that they involve a variety of phenotypes and etiologies (1). Many have signs and symptoms common in heart failure, such as reduced ejection fraction, peripheral edema, fatigue, orthopnea, exertion dyspnea, paroxysmal nocturnal dyspnea ...
Precone, Vincenza, Krasi, Geraldo, Guerri, Giulia, Madureri, Alberto, Piazzani, Mariangela, Michelini, Sandro, Barati, Shila, Maniscalchi, Tiziana, Bressan, Simone, Bertelli, Matteo   +9 more
openaire   +2 more sources

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Role of cardiac MRI in nonischemic cardiomyopathies

Indian Heart Journal, 2016
Cardiac magnetic resonance (CMR) with its higher spatial resolution is considered the gold standard for evaluating ventricular mass, volumes, and ejection fraction. CMR can be used for accurate diagnosis of several conditions, especially cardiomyopathies.
Senthil Anand, Rajesh Janardhanan
doaj   +1 more source

RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]

, 2019
Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue, Kim, Il-man, Shen, Yan, Su, Xuan, Tang, Yaoliang, Weintraub, Neal L.   +5 more
core   +1 more source

A mutation update for the FLNC gene in myopathies and cardiomyopathies

Human Mutation, 2020
Filamin C (FLNC) variants are associated with cardiac and muscular phenotypes. Originally, FLNC variants were described in myofibrillar myopathy (MFM) patients.
J. Verdonschot, Els K. Vanhoutte, G. Claes, A. T. Helderman-van den Enden, J. Hoeijmakers, D. Hellebrekers, Amber de Haan, I. Christiaans, R. L. Lekanne Deprez, H. Boen, E. V. Van Craenenbroeck, B. Loeys, Y. M. Hoedemakers, Carlo L. Marcelis, M. Kempers, Esther Brusse, Jaap I van Waning, Annette F. Baas, Dennis Dooijes, F. Asselbergs, D. Barge-Schaapveld, Pieter Koopman, A. van den Wijngaard, S. Heymans, I. Krapels, Han G. Brunner   +25 more
semanticscholar   +1 more source

The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy

Journal of Feline Medicine and Surgery, 2021
Practical relevance: Hypertrophic cardiomyopathy (HCM) is the most common form of feline cardiomyopathy observed clinically and may affect up to approximately 15% of the domestic cat population, primarily as a subclinical disease. Fortunately, severe HCM, leading to heart failure or arterial thromboembolism (ATE), only occurs in a small proportion of ...
Etienne Côté, Mark D Kittleson
openaire   +3 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Familial screening in case of acute myocarditis reveals inherited arrhythmogenic left ventricular cardiomyopathies

ESC Heart Failure, 2020
Several data suggest that acute myocarditis could be related to genetic variants involved in familial cardiomyopathies, particularly arrhythmogenic cardiomyopathy, but the management of patients with acute myocarditis and their families regarding their ...
N. Piriou, L. Marteau, F. Kyndt, J. Serfaty, C. Toquet, L. Le Gloan, K. Warin-Fresse, D. Guijarro, T. Le Tourneau, E. Conan, A. Thollet, V. Probst, J. Trochu   +12 more
semanticscholar   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Naxos Disease [PDF]

, 2005
Since 1995, according to the World Health Organisation’s classification of cardiomyopathies, Naxos disease has been considered as the recessive form of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C).1 It is a stereotype association of
Protonotarios, Nikos, Tsatsopoulou, Adalena   +1 more
core   +2 more sources