Results 131 to 140 of about 71,934 (217)

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Pediatric cardiomyopathy in a resource-limited setting: clinical characteristics and determinants of medium-term outcomes. [PDF]

Front Med (Lausanne)
Fakhri G, Zareef R, Younis N, Abdul Halim N, Abdul Khalek J, Makarem A, Ibrahim R, Ahmed M, Fuad Bitar F, Toufic Arabi M.   +9 more
europepmc   +1 more source

Homozygous PPP1R13L Mutation Associated with Dilated Cardiomyopathy in a 1-Year-Old Child. [PDF]

Life (Basel)
Sorescu AM, Ghiță CIV, Duică G, Nicolescu A, Cinteză EE, Adorisio R, Amodeo A, Francalanci P, Brancaccio G, Ingrasciotta G, Mencarelli E, Coman OA.   +11 more
europepmc   +1 more source

Sphingosine‐1‐Phosphate Attenuates LPS‐Induced Inflammatory Cardiac Injury in Association With RASGRP1–S100A9–NLRP3 Signaling

Drug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Lipopolysaccharide (LPS) induces endotoxemia‐associated inflammatory cardiac injury rather than classical viral or autoimmune myocarditis. Sphingosine‐1‐phosphate (S1P) regulates cardiovascular and immune responses, predominantly through S1P receptors, but whether it also modulates macrophage‐associated inflammatory signaling during LPS ...
Chaofu Yue, Qiaolin Li, Chunyan Li, Taoxian Yang, Xian Huang, Feng Yue, Qiuyu Long, Rong Li, Rong Lei, Qingsong Ma, Caimei Hu, Qian Yang, Yongjun Yan, Yuan Liu, QinYong Yan, Mei Yang   +15 more
wiley   +1 more source

Cardiomyopathy Following Olanzapine Use in an Octogenarian: A Case Report and Literature Review. [PDF]

Cureus
Abdelmoneim SS, Sole P, De la Cruz Seoane M, Palacio I, Hurtado L, Valdes P, Valle B.   +6 more
europepmc   +1 more source

Deep Learning‐Based Dynamic Segmentation of the Left Atrium in 4D Flow MRI

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2505-2515, November 2026.
ABSTRACT Purpose To design a deep learning pipeline for automated, time‐resolved segmentation of the left atrium (LA) from 4D flow MRI data. Methods We studied 100 individuals including 65 patients with atrial fibrillation (AF) and 35 healthy subjects (HS) resulting in 2530 4D flow MRI time‐volumes acquired in different centers and scanners.
Jonas Leite, Tom Da‐Silva Faria, Marie Shannon Soulez, Khaoula Bouazizi, Perrine Marsac, Elie Mousseaux, Jérôme Lamy, Moussa Gueda Moussa, Olivier Piot, Jacques Feignoux, Daniel Giese, Nicolas Badenco, Estelle Gandjbakhch, Alban Redheuil, Mikaël Laredo, Emilie Bollache, Nadjia Kachenoura   +16 more
wiley   +1 more source

Integrated analysis of MYH6, MYH7, and MYH7B expression and their associated microRNAs in human end-stage heart failure. [PDF]

Front Cardiovasc Med
Červenák Z, Červenák F, Valášková S, Chomaničová N, Katreničová N, Hulman M, Gažová A, Kyselovic J.   +7 more
europepmc   +1 more source

“Two‐For‐One”: 4D Cardiac and Pulmonary MR Imaging From a Single Acquisition Using bSTAR

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2213-2227, November 2026.
ABSTRACT Purpose To generate 4D (3D+time) images of both the heart and lungs using a single volumetric radial free‐breathing bSSFP dual echo acquisition (bSTAR) with two image reconstructions within a single pipeline deployed inline at 0.55 and 1.5 T.
Pierre Daudé, Jordan Taylor, Joseph W. Plummer, Rajiv Ramasawmy, Anastasia Tsakirellis, Joel Moss, W. Patricia Bandettini, Marcus Chen, Adrienne E. Campbell‐Washburn, Ahsan Javed   +9 more
wiley   +1 more source