Results 141 to 150 of about 71,934 (217)

Arrhythmic Risk in Carriers of Predicted Deleterious Rare Variants in Dilated and Arrhythmogenic Cardiomyopathy Genes. [PDF]

JACC Adv
Gandin I, Vergani AM, Massi MC, Paldino A, Setti M, Perotto M, Merlo M, Sinagra G, Barbati G, Di Angelantonio E, Ieva F, Ferro MD.   +11 more
europepmc   +1 more source

Long‐Term Use of Rezafungin: A Case Report and Insights Into Real‐World Access

Transplant Infectious Disease, EarlyView.
Jian Mei Li, Jacqueline E. Clark, Tiffany Wu   +2 more
wiley   +1 more source

A Large‐Scale Cross‐Population Evaluation of Genetic Risk Variants for Dilated Cardiomyopathy in Dobermanns

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Previous studies suggest that genetic risk factors for dilated cardiomyopathy (DCM) in Dobermann dogs may differ between populations, complicating the use of genetic tests across subpopulations. Variants in pyruvate dehydrogenase kinase 4 (PDK4) and titin (TTN) have been associated with DCM in North American Dobermanns, whereas two loci on ...
Alma H. Hulsman, Gwen Flokstra, Christina Kijan, Marilijn van Rumpt, Johannes C. M. Vernooij, Thomas C. Nelson, Sophie Liu, Lieke Vree, Magdalena Harakalova, Ingrid Ljungvall, Jens Haggstrom, Gerhard Wess, Hille Fieten, Marjo K. Hytönen, Hannes Lohi, Frank G. van Steenbeek   +15 more
wiley   +1 more source

Trypanosoma cruzi Cardiomyopathy Diagnosed via Explant Tissue 28S Ribosomal Gene Sequencing Following Orthotopic Heart Transplantation. [PDF]

Cureus
Fernandez AC, Berry GJ, Ahanonu R, Ferguson Toll J.   +3 more
europepmc   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Genetic Testing After Heart Transplantation Uncovers Heritable Disease and Drives Family Screening. [PDF]

JACC Adv
Moliner-Abós C, Cabrera Argaña D, Belmar Cliville D, Rivas S, Crespo-Leiro MG, Peña Hidalgo A, Garrido Gonzalez R, Martín Marín P, Gómez Molina M, Lorca R, Cárdenes León A, González Vilchez F, Rodriguez Arias JJ, Basurte Elorz M, Valverde M, Larrañaga-Moreira JM, Antunez-Ballesteros M, de Frutos F, Rivas-Lasarte M, Manuel Sobrino Márquez J, Garrido Bravo IP, Diaz Molina B, Acosta Calero C, Goena-Vives C, García-Álvarez A, Vilches S, Garcia Romero E, Gomez Bueno M, Garcia Pinilla JM, Alonso Fernandez V, Ochoa JP, de Antonio-Ferrer M, Rodriguez-Santiago B, Mirabet-Pérez S.   +33 more
europepmc   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Temporal trends and post-transplant outcomes in anthracycline-induced cardiomyopathy: A contemporary United Network for Organ Sharing analysis. [PDF]

JHLT Open
Osorio MF, Castillo E, Ariza SV, Gonzalez-Fernandez M, Wever-Pinzon O.   +4 more
europepmc   +1 more source

SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic, Jovana Rajkovic, Radmila Novakovic, Javad Sharifi‐Rad, Daniela Calina   +4 more
wiley   +1 more source

Clinical Variability Including Non-Dilated Left Ventricular and Dilated Cardiomyopathy in a Pedigree With an Intragenic CTNNA3 Copy Number Variation. [PDF]

Clin Genet
Fusco C, Mastroianno S, Morlino S, Pracella R, Russo F, Bevere EML, Palumbo O, Di Stolfo G, Castori M.   +8 more
europepmc   +1 more source