Results 161 to 170 of about 126,108 (297)

Percutaneous Intervention in External Outflow Graft Obstruction of Magnetically Levitated Left Ventricular Assist Device: Long‐Term Follow‐Up and Quality of Life

open access: yesArtificial Organs, EarlyView.
eOGO is an uncommon adverse event in patients on long‐term LVAD support. Thirty‐one eOGO patients were identified in a single‐centre HM3 implantation program. Twenty patients underwent percutaneous stenting. This treatment resulted in immediate LVAD flow improvement and yielded satisfactory quality‐of‐life results, with 62.5% patients assigned a fair ...
Anna Huang   +14 more
wiley   +1 more source

Comparison of Intraoperative Doppler Flow Measurements and Algorithmic Flow Estimations in Patients Undergoing Durable Left Ventricular Assist Device Implantation

open access: yesArtificial Organs, EarlyView.
Direct intraoperative HeartMate 3 LVAD flow measurements using an ultrasonic probe revealed consistently higher values by approximately 0.5 L/min compared to device‐estimated flows. This discrepancy remained stable across pump speed settings, highlighting the importance of distinguishing measured from estimated flow in HeartMate 3 patients.
Gaik Nersesian   +13 more
wiley   +1 more source

Can't Patch Everything: Personalized Medicine for Cell Therapy in Dilated Cardiomyopathy

open access: yes, 2021
Journal of the American Heart Association, EarlyView.
Andrew Sundin   +2 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

open access: yesBrain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland   +4 more
wiley   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena   +5 more
wiley   +1 more source

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

open access: yesClinical Genetics, EarlyView.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis   +9 more
wiley   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

open access: yesThe FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy