Neurocardiac crosstalk in inherited cardiac arrhythmias and cardiomyopathy
Abstract figure legend In inherited cardiac arrhythmias and cardiomyopathy, arrhythmias are typically triggered by autonomic nervous system activity. Genetic mutations linked to these conditions cause pro‐arrhythmic alterations in both cardiomyocytes and neurons, with their pathophysiological crosstalk likely amplifying the manifestation of the disease.
Carol Ann Remme, Molly O'Reilly
wiley +1 more source
Spiked Helmet Sign in the Early Post-Heart Transplantation Period: A Dramatic STEMI Mimic in a Structurally Normal Donor Heart. [PDF]
A 36‐year‐old woman developed Spiked Helmet Sign after heart transplantation complicated by subarachnoid hemorrhage and septic shock. Although the ECG changes resolved, she died from infectious complications, highlighting SHS as a marker of critical illness and poor prognosis.
Lima DRM +5 more
europepmc +2 more sources
The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas +5 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
A retrospective study of mode of delivery in patients with hypertrophic vs other forms of cardiomyopathy. [PDF]
Meng ML +9 more
europepmc +1 more source
Long‐Term Use of Rezafungin: A Case Report and Insights Into Real‐World Access
Transplant Infectious Disease, EarlyView.
Jian Mei Li +2 more
wiley +1 more source
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun +13 more
wiley +1 more source
Temporal evolution of clinical event risk after primary-prevention ICD implantation: Chagas vs. non-Chagas dilated cardiomyopathy. [PDF]
Guzmán JP +7 more
europepmc +1 more source
Timing of Cardiac Contractility Modulation Therapy Implementation
In this retrospective registry analysis, cardiac contractility modulation (CCM) improved functional status and left ventricular ejection fraction whether implanted early or later. Implantation within 12 months after CCM‐eligible heart failure diagnosis might be associated with better survival, greater ejection‐fraction improvement, and fewer heart ...
Goekhan Yuecel +12 more
wiley +1 more source

