ABSTRACT Lipopolysaccharide (LPS) induces endotoxemia‐associated inflammatory cardiac injury rather than classical viral or autoimmune myocarditis. Sphingosine‐1‐phosphate (S1P) regulates cardiovascular and immune responses, predominantly through S1P receptors, but whether it also modulates macrophage‐associated inflammatory signaling during LPS ...
Chaofu Yue +15 more
wiley +1 more source
The Multifaceted Role of the <i>FLNC</i> Gene in Hereditary Cardiomyopathies and Prognosis. [PDF]
D'Apolito M +7 more
europepmc +1 more source
Atherosclerosis: From Pathogenesis to Therapeutic Interventions
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou +9 more
wiley +1 more source
Rapidly Progressive Infantile Dilated Cardiomyopathy in Long-Olsen-Distelmaier Syndrome Associated with <i>RRAGC</i> NM_022157.4:c.343T>C, p.(Trp115Arg): A Case Report. [PDF]
Uddin MS +10 more
europepmc +1 more source
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay +3 more
wiley +1 more source
Trends and In-Hospital Outcomes of Ventricular Tachycardia in Ischemic Versus Non-Ischemic Dilated Cardiomyopathy-An Insight From the Nationwide Readmissions Database (2016-2020). [PDF]
Chowdhury M +9 more
europepmc +1 more source
Sudden cardiac arrest in an athlete due to dilated cardiomyopathy masquerading as athlete's heart: a case report. [PDF]
Hapsari GP +3 more
europepmc +1 more source
Deep Learning‐Based Dynamic Segmentation of the Left Atrium in 4D Flow MRI
ABSTRACT Purpose To design a deep learning pipeline for automated, time‐resolved segmentation of the left atrium (LA) from 4D flow MRI data. Methods We studied 100 individuals including 65 patients with atrial fibrillation (AF) and 35 healthy subjects (HS) resulting in 2530 4D flow MRI time‐volumes acquired in different centers and scanners.
Jonas Leite +16 more
wiley +1 more source
Arrhythmic Risk Stratification in Non-Ischaemic Cardiomyopathy: The Role of Cardiac Magnetic Resonance Imaging. [PDF]
Sia RI, Hammersley DJ.
europepmc +1 more source
“Two‐For‐One”: 4D Cardiac and Pulmonary MR Imaging From a Single Acquisition Using bSTAR
ABSTRACT Purpose To generate 4D (3D+time) images of both the heart and lungs using a single volumetric radial free‐breathing bSSFP dual echo acquisition (bSTAR) with two image reconstructions within a single pipeline deployed inline at 0.55 and 1.5 T.
Pierre Daudé +9 more
wiley +1 more source

