Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Haemochromatosis ‐ a modern clinician’s guide
Abstract Haemochromatosis is an inherited disorder of iron metabolism affecting approximately 100 000 Australians. Iron overload may result in end organ dysfunction, most commonly manifesting as chronic liver disease, arthropathy and endocrinopathies. End organ complications can be prevented, minimised or reversed, with early diagnosis and initiation ...
James G. Fiori, John K. Olynyk
wiley +1 more source
"Burned-Out" Hypertrophic Cardiomyopathy: Overlap on Cardiac MRI With Other Nonischemic Cardiomyopathies. [PDF]
Wunderly K +3 more
europepmc +1 more source
Efficacy and Safety of Dronedarone in Overweight and Obesity: Post Hoc Analysis of the ATHENA Trial
ABSTRACT Introduction Obesity represents a prevalent condition with multiple comorbidities, including atrial fibrillation (AF). Dronedarone, an antiarrhythmic drug (AAD), has demonstrated efficacy in patients with paroxysmal/persistent AF and cardiovascular (CV) risk factors.
Mate Vamos +3 more
wiley +1 more source
Digenic sarcomeric variants in paediatric dilated cardiomyopathy and maternal peripartum cardiomyopathy: a familial case report. [PDF]
Kurt H +4 more
europepmc +1 more source
Clinical Prediction Model for Unsuccessful Left Bundle Branch Area Pacing
A clinical prediction model based on NIVCD, interventricular septal thickness, and right atrial area enables individualized estimation of unsuccessful LBBAP and may help guide procedural strategy. ABSTRACT Introduction Left bundle branch area pacing (LBBAP) has rapidly become a preferred form of cardiac physiologic pacing; however, predictors of ...
Yousaku Okubo +13 more
wiley +1 more source
Genotype-phenotype correlations in patients with pathogenic/likely pathogenic titin variants from the Swiss Arrhythmogenic Cardiomyopathy Registry. [PDF]
Schätti NA +19 more
europepmc +1 more source
ABSTRACT Background and Aims Transvenous lead extraction (TLE) is increasingly performed for malfunction or infection of cardiac implantable electronic devices (CIED). Active mechanical rotational sheaths facilitate extraction and are available in short and long sizes, but it is unclear how many patients short active mechanical extraction sheaths ...
Caroline Wiederkehr +6 more
wiley +1 more source
Integrated heart-blood RNA editome profiling reveals circulating A-to-I editing candidates linked to dilated cardiomyopathy myocardial signatures and heart failure. [PDF]
Karagianni K +5 more
europepmc +1 more source
Left bundle branch area pacing is associated with preservation of ventricular function in patients with bradycardia indications and with significant reverse remodeling and symptomatic improvement in patients with heart failure. Maintaining a high percentage of effective LBBAP capture is critical to minimize the risk of pacing‐induced cardiomyopathy and
Gabriele Dell'Era +32 more
wiley +1 more source

