Results 171 to 180 of about 194,403 (293)

Expanding the Clinical Spectrum of DHX30‐Related Neurodevelopmental Disorder: A Case Report and a Scoping Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Whole exome sequencing (WES) has improved diagnostic rates for neurodevelopmental disorders (NDDs) while introducing challenges in novel variant interpretation. DHX30‐related NDD (DHX30‐NDD) is a recently described condition with an evolving phenotypic spectrum.
Nattaporn Tassanakijpanich, Areerat Hnoonual, Oradawan Plong‐On, Pornprot Limprasert   +3 more
wiley   +1 more source

Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures

Pacing and Clinical Electrophysiology, EarlyView.
Graphical Abstract ABSTRACT Fluoroscopy has traditionally been the mainstay imaging technique for guidance during electrophysiology (EP) ablation procedures. The numerous disadvantages associated with radiation exposure for both operators and patients have created the need for zero‐fluoroscopy (ZF) approaches. Today, electrophysiologists have access to
Dimitrios Kotzadamis, Georgios Giannopoulos, Vaios Schismenos, Alexandros Evangeliou, Prokopios Mamolis, Antonios Antoniadis, Vassilios Vassilikos   +6 more
wiley   +1 more source

Case Report: When cardiomyopathy is the clue: late-presenting propionic acidemia manifesting as acute heart failure. [PDF]

Front Pediatr
Nti BK, Trapp N, Ali A, Lanpher B, Weatherhead J.   +4 more
europepmc   +1 more source

Inpatient Cardiac Resynchronization Therapy During Heart Failure Hospitalization: A Distinct High‐Risk Phenotype

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The role of cardiac resynchronization therapy (CRT) during hospitalization for heart failure (HFH) is uncertain, because hospitalized patients were routinely excluded from landmark CRT trials. Despite this, CRT implantation during HFH is common.
Oliver Rees, James Dargan, Jemima Weir, Robin Ray, Giuseppe Rosano, Fadi Johura   +5 more
wiley   +1 more source

Ventricular Synchrony in Targeted Right Ventricular Septal Pacing: A Prospective Paired Comparison to Apical Placement

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background/Objectives Right ventricular (RV) apical pacing, the standard pacing approach, often induces ventricular dyssynchrony, potentially impairing cardiac function. This study aims to investigate whether targeted RV septal pacing, guided by functional electrophysiological feedback during implantation, reduces ventricular dyssynchrony ...
Bianca Iulia Catrina, Mihai Octavian Negrea, Ciprian Tănăsescu, Florina Batar, Florin‐Leontin Lazar, Ioan Manitiu   +5 more
wiley   +1 more source

Cardiomyopathies: Current Treatment and Future Options

The reprint highlights different forms of cardiomyopathy, such as RBM20, filamin C, and lamin A/C cardiomyopathy. Diagnostic and new treatment options are presented in arrhythmogenic, hypertrophic, dilated, and restrictive cardiomyopathy.

core   +1 more source

Doxorubicin‐induced Cardiotoxicity in Dogs: A Narrative Review

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Doxorubicin, an anthracycline widely used in both human and veterinary oncology, is highly effective against a variety of malignancies in dogs, including lymphomas, sarcomas and carcinomas. Despite its efficacy, doxorubicin exposure can be associated with cardiotoxicity, which may present acutely or chronically, potentially leading to severe ...
Supita Sunpongsri, Tom Roos, Ronette Gerhing, Maurice Zandvliet, Giorgia Santarelli   +4 more
wiley   +1 more source

Galectin‐3 plasma levels are associated with left atrial contractile function in long‐distance runners

Experimental Physiology, EarlyView.
Abstract High‐intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis‐related biomarkers and whether these biomarkers track ...
Felipe Contreras‐Briceño, Fernanda Sanhueza‐Olivares, Rodrigo Fernández, Silvana Llevaneras, Pablo F. Castro, Luigi Gabrielli, Mario Chiong   +6 more
wiley   +1 more source

Metabolic stress exacerbates Ca2+ dysregulation and arrhythmias in catecholaminergic polymorphic ventricular tachycardia

Experimental Physiology, EarlyView.
Abstract Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic arrhythmic syndrome caused by mutations in the sarcoplasmic reticulum (SR) calcium (Ca2+) release channel RyR2 or its accessory proteins, including calsequestrin‐2 (CASQ2).
Valeria Gomez, Arpita Deb, Zhuoxin Li, Yujia Cheng, Benjamin K. Fischer, Jinying Yang, Jeongmin Lee, Bjorn C. Knollmann, Zhiyong Cheng, Bin Liu   +9 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source