Results 251 to 260 of about 120,376 (304)

Nuclear damage-induced DNA damage response coupled with IFI16-driven ECM remodeling underlies dilated cardiomyopathy. [PDF]

Theranostics
He Q, Chang X, Zhang H, Hao Q, Zhi J, Shi H, Tian Y, Zhou H, Tan Y, Zheng J, Qiu J, Tao J.   +11 more
europepmc   +1 more source

Mitochondrial Mutation Leads to Cardiomyocyte Hypertrophy by Disruption of Mitochondria‐Associated ER Membrane

Cell Proliferation, EarlyView.
Cardiomyocytes with high m.3243A>G burden exhibited hypertrophic phenotype. Mitochondria dysfunction occurred and tended to become round in cardiomyocytes with high m.3243A>G burden. Mitochondria‐associated ER membrane (MAM) was disrupted in cardiomyocytes with high m.3243A>G burden.
Miao Yu, Min Song, Manna Zhang, Shuangshuang Chen, Baoqiang Ni, Xuechun Li, Wei Lei, Zhenya Shen, Yong Fan, Jianyi Zhang, Shijun Hu   +10 more
wiley   +1 more source

An Unusual Case of 11αB-Crystallin (CRYAB) Mutation as a Cause of Dilated Cardiomyopathy With Restrictive Physiology: A Case Report and Focused Review of the Literature. [PDF]

Clin Case Rep
Cristian Orlando PB, Roberto Hernando CB, Alejandro MC, Edward Andres CM, Meek E, Edgar Giovanni RD.   +5 more
europepmc   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and outcomes in transthyretin amyloid cardiomyopathy: Systematic review and meta‐analysis

European Journal of Clinical Investigation, Volume 55, Issue 6, June 2025.
Patients with transthyretin amyloid cardiomyopathy (ATTR‐CM) were excluded from randomized clinical trials (RCTs) evaluating sodium‐glucose cotransporter 2 inhibitors (SGLT2i); as a result, the effects of these agents on this population remain underexplored.
Paschalis Karakasis, Panagiotis Theofilis, Dimitrios Patoulias, Art Schuermans, Panayotis K Vlachakis, Aleksandra Klisic, Manfredi Rizzo, Nikolaos Fragakis   +7 more
wiley   +1 more source

Echocardiography and Heart Failure: An Echocardiographic Decision Aid for the Diagnosis and Management of Cardiomyopathies. [PDF]

Curr Cardiol Rep
Pender A, Lewis-Owona J, Ekiyoyo A, Stoddard M.   +3 more
europepmc   +1 more source

Effects of 4‐month treatment with glycocalyx dietary supplement on endothelial glycocalyx and vascular function after COVID‐19 infection

European Journal of Clinical Investigation, EarlyView.
The present study aimed to investigate the effect of glycocalyx dietary supplement (GDS), containing glucosamine sulfate and fucoidan, on endothelial glycocalyx integrity and vascular function in subjects after mild‐to‐moderate COVID‐19 infection managed in an outpatient setting.
George Pavlidis, Aikaterini Kountouri, Konstantinos Katogiannis, John Thymis, Panagiota Efstathia Nikolaou, Christina Chania, John Karalis, Gabriella Kostelli, Eleni Michalopoulou, Eleni Katsanaki, John Parissis, Hans Vink, Robert Long, Sotirios Tsiodras, Vaia Lambadiari, Ignatios Ikonomidis   +15 more
wiley   +1 more source

Recent advances in multimodality imaging‐guided therapy in pericarditis

European Journal of Clinical Investigation, EarlyView.
Multiple imaging targets have been identified as essential biomarkers to confirm pericardial thickening, edema, neovascularization, inflammation, fibrosis/calcification, cardiac tamponade physiology, and constriction. This novel approach is called imaging‐guided therapy, which guides anti‐inflammatory therapy, assesses treatment response, assists in ...
Joseph El Roumi, Aldo L. Schenone, Paul Cremer, Tom Kai Ming Wang, Allan Klein   +4 more
wiley   +1 more source

Cardiomyopathy as the forgotten symptom of systemic lupus erythematosus in children: A case report. [PDF]

Narra J
Yudhianto E, Malisie RF, Abdillah HZ, Rusli RE.   +3 more
europepmc   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source