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Dilated cardiomyopathy: a review
Journal of Clinical Pathology, 2008Dilated cardiomyopathy (DCM) is a common cardiac diagnosis that may result as a consequence of a variety of pathologies. The differential diagnosis remains quite broad since many pathologies can present as DCM, and as a result the approach to diagnosis may, at times, be quite difficult.
A, Luk, E, Ahn, G S, Soor, J, Butany
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Genetics in Dilated Cardiomyopathy
Biomarkers in Medicine, 2013Discoveries made during the last 20 years have revealed a genetic origin in many cases of dilated cardiomyopathy (DCM). Currently, over 40 genes have been associated with the disease. Mutations in DCM-causing genes induce the condition through a variety of different pathological pathways with complex and not completely understood mechanisms. Genes that
Pablo, Garcia-Pavia +7 more
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Pharmacotherapy of Dilated Cardiomyopathy
Current Pharmaceutical Design, 2014The pharmacological treatment of dilated cardiomyopathy overlaps with the treatment of heart failure. The primary objective of this treatment is to slow the progression of disease and improve quality and length of life. All patients, including those with asymptomatic dysfunction of the left ventricle, ought to receive angiotensin converting enzyme ...
Lenka, Spinarova, Jindrich, Spinar
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Immunoadsorption in Dilated Cardiomyopathy
2006Dilated cardiomyopathy (DCM) is characterized by progressive reduction in contractile function and by dilatation of the right and left ventricles. Abnormalities of the cellular and humoral immune system are present in patients with myocarditis and DCM. Several antibodies against cardiac structures have been detected in DCM patients.
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Immunoadsorption in Dilated Cardiomyopathy
Therapeutic Apheresis, 2000Abstract: The prognosis for patients suffering from advanced stages of dilated cardiomyopathy (DCM) is poor. Recent studies have shown that immunoadsorption (IA) may represent an effective alternative therapeutic approach for other kinds of autoimmune diseases with circulating autoantibodies. The objective of this pilot study was to ascertain the short‐
W V, Dörffel +3 more
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Immunosuppression for Dilated Cardiomyopathy
New England Journal of Medicine, 1989The diagnosis of dilated cardiomyopathy is made when left ventricular dilatation and systolic dysfunction, with normal wall thickness, occur in the absence of coronary artery, valvular, or pericardial disease.1 The right ventricle is also often involved.
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[Etiopathogenesis of dilated cardiomyopathies].
Cardiologia (Rome, Italy), 1993This study was carried out on 43 patients affected by dilated cardiomyopathy to investigate some of the etiopathological hypotheses on this illness. The Authors investigated: the persistence of virus genoma (coxsackie, HBV) on endomyocardial biopsies; the pattern of the II class major histocompatibility complex (MHC) were in the blood lymphocytes; the ...
PETRONIO, ANNA +7 more
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Rare Variant Genetics and Dilated Cardiomyopathy Severity: The DCM Precision Medicine Study
Circulation, 2023Garrie J Haas +2 more
exaly
Genetics of dilated cardiomyopathy: practical implications for heart failure management
Nature Reviews Cardiology, 2019A. Rosenbaum +2 more
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