Results 251 to 260 of about 194,403 (293)

Genetics of Dilated Cardiomyopathy

Heart Failure Clinics, 2010
Dilated cardiomyopathy (DCM) is a myocardial disorder defined by ventricular chamber enlargement and systolic dysfunction. DCM can result in progressive heart failure, arrhythmias, thromboembolism, and premature death, and contributes significantly to health care costs. In many cases, DCM results from acquired factors that affect cardiomyocyte function
Diane, Fatkin, Robyn, Otway, Zara, Richmond   +2 more
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Familial dilated cardiomyopathy

American Journal of Medical Genetics, 1988
AbstractIdiopathic dilated cardiomyopathy is generally considered a sporadic, nongenetic disorder, and reports of familial cases are often regarded as rare occurrences. Results of the present investigation of 6 families with this disorder suggest that familial forms of dilated cardiomyopathy occur more frequently than previously suspected. The familial
Michael A. Schmidt, Virginia V. Michels, William D. Edwards, Fletcher A. Miller, John M. Opitz, James F. Reynolds   +5 more
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Dilated cardiomyopathy: a review

Journal of Clinical Pathology, 2008
Dilated cardiomyopathy (DCM) is a common cardiac diagnosis that may result as a consequence of a variety of pathologies. The differential diagnosis remains quite broad since many pathologies can present as DCM, and as a result the approach to diagnosis may, at times, be quite difficult.
A, Luk, E, Ahn, G S, Soor, J, Butany
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Living with dilated cardiomyopathy

BMJ, 2016
Richard Mindham has been living with the diagnosed condition for nine years and shares his experiences as a ...
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Genetics in Dilated Cardiomyopathy

Biomarkers in Medicine, 2013
Discoveries made during the last 20 years have revealed a genetic origin in many cases of dilated cardiomyopathy (DCM). Currently, over 40 genes have been associated with the disease. Mutations in DCM-causing genes induce the condition through a variety of different pathological pathways with complex and not completely understood mechanisms. Genes that
Pablo, Garcia-Pavia, Marta, Cobo-Marcos, Gonzalo, Guzzo-Merello, Manuel, Gomez-Bueno, Belen, Bornstein, Enrique, Lara-Pezzi, Javier, Segovia, Luis, Alonso-Pulpon   +7 more
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Inflammation in Dilated Cardiomyopathy

Herz, 2004
Inflammation is an important component in the pathogenesis of many common cardiovascular diseases. In most cases, the role of inflammation is a natural response to injury, and an important mechanism for healing and tissue repair. However, the inflammatory response can be either inadequate or overwhelming, leading to direct injury or severe host disease.
Sabine, Pankuweit, Volker, Ruppert, Bernhard, Maisch   +2 more
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Arrhythmias in Dilated Cardiomyopathy

Cardiac Electrophysiology Clinics, 2015
Patients with dilated cardiomyopathies (DCM) face a significant burden of arrhythmias, including conduction defects such as atrioventricular block and interventricular delay in the form of left bundle branch block, resulting in altered electromechanical coupling that can exacerbate heart failure.
Saurabh, Kumar, William G, Stevenson, Roy M, John   +2 more
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Dilated cardiomyopathy: an update

Veterinary Clinics of North America: Small Animal Practice, 2004
Despite many advances in he diagnosis and treatment of DCM, it continues to be an important cause of cardiovascular morbidity and mortality in large-breed dogs. In the coming years, it is hoped and anticipated tht further discoveries will be made in the areas of etiology, therapy, and assessment of prognosis, ultimately with a view to having a greater ...
Michael R, O'Grady, M Lynne, O'Sullivan
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Pharmacotherapy of Dilated Cardiomyopathy

Current Pharmaceutical Design, 2014
The pharmacological treatment of dilated cardiomyopathy overlaps with the treatment of heart failure. The primary objective of this treatment is to slow the progression of disease and improve quality and length of life. All patients, including those with asymptomatic dysfunction of the left ventricle, ought to receive angiotensin converting enzyme ...
Lenka, Spinarova, Jindrich, Spinar
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Immunoadsorption in Dilated Cardiomyopathy

Therapeutic Apheresis, 2000
Abstract: The prognosis for patients suffering from advanced stages of dilated cardiomyopathy (DCM) is poor. Recent studies have shown that immunoadsorption (IA) may represent an effective alternative therapeutic approach for other kinds of autoimmune diseases with circulating autoantibodies. The objective of this pilot study was to ascertain the short‐
W V, Dörffel, G, Wallukat, G, Baumann, S B, Felix   +3 more
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