Results 41 to 50 of about 85,404 (309)

Innate immune activation in experimental autoimmune myocarditis [PDF]

, 2007
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and frequently results from postinfectious autoimmunity. Its pathophysiology is modeled by experimental autoimmune myocarditis (EAM), a CD4+ T-cell mediated murine model of ...
Marty, René Roger
core   +1 more source

Prospective Evaluation of the Utility of Whole Exome Sequencing in Dilated Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Dilated cardiomyopathy may be heritable but shows extensive genetic heterogeneity. The utility of whole exome sequencing as a first‐line genetic test for patients with dilated cardiomyopathy in a contemporary “real‐world” setting has not been ...
Jay Ramchand, Mathew Wallis, Ivan Macciocca, Elly Lynch, Omar Farouque, Melissa Martyn, Dean Phelan, Belinda Chong, Siobhan Lockwood, Robert Weintraub, Tina Thompson, Alison Trainer, Dominica Zentner, Jitendra Vohra, Michael Chetrit, David L. Hare, Paul James   +16 more
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Dilated cardiomyopathy in childhood [PDF]

, 2000
Dilated Cardiomyopathy is an uncommon disease in children but morbidity and mortality in affected patients are high. This review discuses clinical presentation, diagnosis, medical management and prognosis of the condition, with an emphasis on recent ...
Franklin, O.M.
core  

A young man with acute dilated cardiomyopathy associated with methylphenidate [PDF]

, 2008
Tor-Bjarne Nymark1, A Hovland2, H Bjørnstad2, E W Nielsen1,31Section for Emergency Medicine; 2Department of Cardiology, Nordland Hospital, Bodø, Norway; 3University of Tromsø, Tromsø, NorwayAbstract: An 18-year-old obese man ...
H Bjørnstad, Nymark, Tor Bjarne, Hovland, Anders W., E W Nielsen, A Hovland, Nielsen, Erik Waage, Tor-Bjarne Nymark, Bjørnstad, Hanne   +7 more
core   +1 more source

‐related dilated cardiomyopathy presenting in late infancy [PDF]

, 2022
Leiomodin-2 (LMOD2) is an important regulator of the thin filament length, known to promote elongation of actin through polymerization at pointed ends.
Seema R. Lalani, Worley, Kim, Erica Lay, Spinner, Joseph A., Susan W. Denfield, Kearney, Debra, Kim C. Worley, Azamian, Mahshid S., William Dreyer, Debra Kearney, Lilei Zhang, Lalani, Seema R., Mahshid S. Azamian, Dreyer, William, Denfield, Susan W, Bi, Weimin, Joseph A. Spinner, Azamian, Mahshid S, Denfield, Susan W., Zhang, Lilei, Weimin Bi, Lalani, Seema R, Worley, Kim C, Lay, Erica, Spinner, Joseph A   +24 more
core   +2 more sources

Cardiomyopathy, familial dilated [PDF]

Orphanet Journal of Rare Diseases, 2006
AbstractDilated cardiomyopathy (DCM) is a heart muscle disease characterized by ventricular dilatation and impaired systolic function. Patients with DCM suffer from heart failure, arrhythmia, and are at risk of premature death. DCM has a prevalence of one case out of 2500 individuals with an incidence of 7/100,000/year (but may be under diagnosed).
Mestroni Luisa, Carniel Elisa, Taylor Matthew RG   +2 more
openaire   +3 more sources

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Rhinovirus-associated dilated cardiomyopathy [PDF]

, 2020
Rhinovirus is the main cause of the common cold. There is little to no published literature of rhinoviral associated myocarditis. We report a rare case of rhinovirus infection in a patient with myocarditis leading to dilated cardiomyopathy.
Jeffrey Chow, Ashish Subedi, Joey Murphy, Amudhan Jyothidasan   +3 more
core   +1 more source

Familial dilated cardiomyopathy [PDF]

Heart, 1994
ardiomyopathies are diseasesof the heart muscle that renderthe heart unable to properlypump enough blood to the body. In thedilated form of cardiomyopathy(called dilated cardiomyopathy orDCM), the heart is enlarged (Figure 1).As the heart enlarges, it becomes lesseffective in pumping blood, whichthen leads to symptoms of heart failureand irregular ...
L. Mestroni, M. Krajinovic, G. M. Severini, B. Pinamonti, A. D. Lenarda, GIACCA, MAURO, A. Falaschi, F. Camerini   +7 more
openaire   +3 more sources