Results 61 to 70 of about 591,365 (304)

Feature-tracking global longitudinal strain predicts death in a multicenter population of patients with ischemic and non-ischemic dilated cardiomyopathy incremental to ejection fraction and late gadolinium enhancement

JACC Cardiovascular Imaging, 2018
Objectives The aim of this study was to evaluate the prognostic value of Cardiac-Magnetic-Resonance (CMR) feature-tracking derived global-longitudinal-strain (GLS) in a large multicenter population of patients with ischemic and non-ischemic dilated ...
S. Romano, R. Judd, R. Kim, Han W. Kim, I. Klem, J. Heitner, D. Shah, J. Jue, Brent E. White, R. Indorkar, C. Shenoy, A. Farzaneh-Far   +11 more
semanticscholar   +1 more source

Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier, Jodi Warman‐Chardon, Danielle K. Bourque   +2 more
wiley   +1 more source

Research Progress and Forensic Identification of Alcoholic Cardiomyopathy [PDF]

Fayixue Zazhi, 2019
With the rapid development of the social economy in China, the incidence of diseases caused by excessive drinking is gradually increasing as well. Alcoholic cardiomyopathy refers to long-term high intake of ethanol, and has typical dilated cardiomyopathy
ZHANG Tian-yi, GAO Wei-min, CAO Zhi-peng,et al.
doaj   +1 more source

Determinants of minute ventilation-carbon dioxide production relationship in Chagas cardiomyopathy

Revista da Sociedade Brasileira de Medicina Tropical, 2021
INTRODUCTION: The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) is among the main prognostic factors of Chagas cardiomyopathy whose determinants remain unknown. METHODS: Seventy-eight patients with Chagas cardiomyopathy were
Lucas Frois Fernandes Oliveira, Janaina Martins Andrade, Pedro Henrique Scheidt Figueiredo, Matheus Ribeiro Ávila, Whesley Tanor Silva, Marcus Vinicius Accetta Vianna, Renato Guilherme Trede Filho, Henrique Silveira Costa, Manoel Otávio Costa Rocha, Vanessa Pereira Lima   +9 more
doaj   +1 more source

RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

Circulation, 2018
Background: Mutations in RBM20 (RNA-binding motif protein 20) cause a clinically aggressive form of dilated cardiomyopathy, with an increased risk of malignant ventricular arrhythmias.
M. V. D. van den Hoogenhof, Abdelaziz Beqqali, A. Amin, Ingeborg van der Made, Simona Aufiero, Mohsin A. F. Khan, C. Schumacher, Joeri A Jansweijer, K. van Spaendonck-Zwarts, C. Remme, J. Backs, A. Verkerk, A. Baartscheer, Y. Pinto, E. Creemers   +14 more
semanticscholar   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source

Dilated cardiomyopathy in children

Journal of the American College of Cardiology, 1988
Dilated cardiomyopathy is a rare but serious disease in children. Clinical manifestations are primarily due to impaired systolic function of the left ventricle. Diagnostic evaluation is important to exclude masquerading cardiac abnormalities and to assess the degree of myocardial dysfunction.
openaire   +2 more sources

Normal Coronary Artery Patient Presenting with Left Ventricular Aneurysm

Case Reports in Medicine, 2011
Left ventricular aneurysm (LVA) is one of the most important complications of myocardial infarction LVA is strictly defined as a distinct area of abnormal left ventricular diastolic contour with systolic dyskinesia or paradoxical bulging.
Hakan Altay, Cihan Altin, Ali Çoner, Haldun Muderrisoglu   +3 more
doaj   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy

Circulation, 2017
Background: Myocardial metabolic impairment is a major feature in chronic heart failure. As the major coenzyme in fuel oxidation and oxidative phosphorylation and a substrate for enzymes signaling energy stress and oxidative stress response, nicotinamide
N. Diguet, Samuel A. J. Trammell, C. Tannous, R. Deloux, J. Piquereau, N. Mougenot, Anne Gouge, Mélanie Gressette, B. Manoury, Jocelyne Blanc, Marie Breton, J. Decaux, G. Lavery, I. Baczkó, J. Zoll, A. Garnier, Zhenlin Li, C. Brenner, M. Mericskay   +18 more
semanticscholar   +1 more source