Results 111 to 120 of about 91,175 (237)

CTCF Point Mutation at R567 Disrupts Mouse Heart Development via 3D Genome Rearrangement and Transcription Dysregulation

Cell Proliferation, Volume 58, Issue 4, April 2025.
The CtcfR567W/R567W mutation disrupted the TAD structure specific to cardiac genes and reduced the interaction between the promoter of cardiac‐specific gene and its enhancer, finally causing the cardiac morphological abnormalities during mouse embryonic development.
Huawei Ren, Hongxin Zhong, Jie Zhang, Yuli Lu, Gongcheng Hu, Weixun Duan, Ning Ma, Hongjie Yao   +7 more
wiley   +1 more source

Mitochondrial Mutation Leads to Cardiomyocyte Hypertrophy by Disruption of Mitochondria‐Associated ER Membrane

Cell Proliferation, EarlyView.
Cardiomyocytes with high m.3243A>G burden exhibited hypertrophic phenotype. Mitochondria dysfunction occurred and tended to become round in cardiomyocytes with high m.3243A>G burden. Mitochondria‐associated ER membrane (MAM) was disrupted in cardiomyocytes with high m.3243A>G burden.
Miao Yu, Min Song, Manna Zhang, Shuangshuang Chen, Baoqiang Ni, Xuechun Li, Wei Lei, Zhenya Shen, Yong Fan, Jianyi Zhang, Shijun Hu   +10 more
wiley   +1 more source

Elevated COMMD1 Contributes to Cardiomyocyte Copper Efflux in Chronic Myocardial Ischemia: Insights From Rhesus Monkey

Cell Proliferation, EarlyView.
Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li, Da Li, Xia Cheng, Xiaoli Yuan, Ning Du, Xin Liao, Xiaorong Feng, Jie Yao, Chenglong Li, Chengxia Xie, Mu Yang   +10 more
wiley   +1 more source

Comparison of plasma metabolic profiling between children with hypertrophic obstructive cardiomyopathy and healthy controls. [PDF]

Cardiovasc Endocrinol Metab
Dong S, Du C, Cui H, Dong J, Liu S, Xu H, Sun Y, Zou M, Song J, Yan J.   +9 more
europepmc   +1 more source

Imaging predictors of adverse prognosis in Fabry disease cardiomyopathy: A systematic review and meta‐analysis

European Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
In this systematic review and meta‐analysis assessing the prognostic relevance of cardiac imaging parameters on adverse outcomes in patients with Fabry disease, we found that late gadolinium enhancement, left atrium volume indexed, E/e′ ratio, left ventricular (LV) mass indexed, maximum LV wall thickness and LV‐global longitudinal strain were ...
Kamil Stankowski, Stefano Figliozzi, Thanakorn Rojanathagoon, Dimitrios Bampatsias, Dimitrios Klettas, Lorenzo Monti, Renato Bragato, Pier‐Giorgio Masci, Marco Francone, Gianluigi Condorelli, Massimo Imbriaco, Maurizio Pieroni, Antonia Camporeale, Georgios Georgiopoulos   +13 more
wiley   +1 more source

Relationship Between Cardiac Troponin I Concentration and Myocardial Function in Hypertrophic Cardiomyopathy Cats With or Without Left Ventricular Outflow Tract Obstruction. [PDF]

Animals (Basel)
Satomi S, Suzuki R, Yuchi Y, Yoshii Y, Kanno H, Teshima T, Matsumoto H.   +6 more
europepmc   +1 more source

The UMPIRE study: A first‐in‐human multicenter trial of bilateral subscalp monitoring for epileptic seizure detection

Epilepsia, EarlyView.
Abstract Objective Patient self‐report is known to be an inaccurate reflection of true seizure frequency in persons with epilepsy. The current study aimed to assess the safety and performance of the Minder system, a bilateral subscalp electroencephalographic (EEG) acquisition system for continuous long‐term EEG recording.
Amy J. Halliday, Lisa Gillinder, Alan Lai, Udaya Seneviratne, Holly Fontenot, Tracy Cameron, Karen McLean, Andrew Niemiec, Ramya Raghupathi, Taneeta M. Ganguly, Colin Ellis, Erin C. Conrad, Robert Briggs, Kristian Bulluss, Patrick Kwan, Piero Perucca, Terence J. O'Brien, Aileen McGonigal, Matthew Gutman, Jason Papacostas, Michael W. K. Fong, Andrew Lee, Douglas E. Crompton, Joshua Laing, Manori Wijayath, Andrew P. Morokoff, Michael Murphy, Wendyl J. D'Souza, Mark J. Cook   +28 more
wiley   +1 more source

Biomarkers of cardiovascular stress and fibrosis in preclinical hypertrophic cardiomyopathy [PDF]

, 2017
Canter, Charles, et al,
core   +1 more source

Atrial Fibrillation (AF) and Heart Failure With Preserved Ejection Fraction (HFpEF): Advances and Challenges

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT This state‐of‐the‐art review is based on the Philippe Coumel Lecture in 2024 (Figure 1). It highlights the confluence of two major cardiovascular epidemics, atrial fibrillation and heart failure, with preserved ejection fraction. In these conditions, advances in electrophysiology and heart failure physiology are intertwined and are integrated ...
Sanjeev Saksena, April Slee, Ranghadham Nagarakanti, Atul Prakash   +3 more
wiley   +1 more source

Patterns of left ventricular trabeculation in hypertrophic cardiomyopathy. [PDF]

BMC Med
Zhang Y, Zhou D, Zhu Y, Huang Q, Wang J, Zhang C, Kang L, Lu M, Song L.   +8 more
europepmc   +1 more source