Results 131 to 140 of about 46,771 (265)

Plasticity of Gene Expression in Spaceflight and Postflight in Relation to Cardiovascular Disease: Mechanisms and Candidate Repurposed Drugs

PROTEOMICS, EarlyView.
ABSTRACT Spaceflight poses unique challenges to human health due to exposure to increased levels of cosmic radiation, microgravity, and associated oxidative stress. These environmental factors can lead to cellular damage, inflammation, and a range of health complications, including cardiovascular problems, immune system impairment, and an increased ...
Marilena M. Bourdakou, Eleni M. Loizidou, George M. Spyrou   +2 more
wiley   +1 more source

Cardiac Myosin Inhibitors as a Novel Treatment Option for Obstructive Hypertrophic Cardiomyopathy: Addressing the Core of the Matter

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Ahmad Masri, Iacopo Olivotto
doaj   +1 more source

Unveiling Clinical and Genetic Distinctions in Pure‐Apical Versus Distal‐Dominant Apical Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Original apical hypertrophic cardiomyopathy was characterized by left ventricular hypertrophy confined to the apex below the papillary muscle level.
Kenta Sugiura, Toru Kubo, Shunsuke Inoue, Seitaro Nomura, Takanobu Yamada, Takashige Tobita, Yuki Kuramoto, Yohei Miyashita, Yoshihiro Asano, Yuri Ochi, Kazuya Miyagawa, Yuichi Baba, Tatsuya Noguchi, Takayoshi Hirota, Naohito Yamasaki, Hiroyuki Morita, Issei Komuro, Hiroaki Kitaoka   +17 more
doaj   +1 more source

Synthetic ultrasound images to benchmark echocardiography-based biomechanics [PDF]

arXiv
Brightness mode (B-mode) ultrasound is a common imaging modality in the clinical assessment of several cardiovascular diseases. The utility of ultrasound-based functional indices such as the ejection fraction (EF) and stroke volume (SV) is widely described in diagnosing advanced-stage cardiovascular diseases.
arxiv  

Septal Reduction Therapy for Obstructive Hypertrophic Cardiomyopathy: Volume Still Matters for Septal Myectomy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Vincent Y. See, Libin Wang
doaj   +1 more source

Elucidating the cellular determinants of the end-systolic pressure-volume relationship of the heart via computational modelling [PDF]

arXiv
The left ventricular end-systolic pressure-volume relationship (ESPVr) is a key indicator of cardiac contractility. Despite its established importance, several studies suggested that the mechanical mode of contraction, such as isovolumetric or ejecting contractions, may affect the ESPVr, challenging the traditional notion of a single, consistent ...
arxiv  

Characterization and differentiation of myocardial remodeling using artificial intelligence‐assisted confocal Raman spectroscopy imaging

VIEW, EarlyView.
Myocardial remodeling is a key factor in heart failure. Rats were treated with ISO to induce remodeling, confirmed by echocardiography and staining. Confocal Raman spectroscopy imaging provided detailed insights into tissue architecture and the differentiation of regions.
Renxing Song, Xunyi Yin, Manlin Zhu, Xinyu Chen, Zhen Zhang, Xiaoming Lyu, Shuang Jiang, Zhehan Liu, Yuting Li, Zhaoying Zhang, Tao Ban, Yang Li   +11 more
wiley   +1 more source

Indications for Surgery in Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Mark V. Sherrid
doaj   +1 more source

Paediatric Hypotrichosis: A Clinical and Algorithmic Approach to Diagnosis

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Paediatric hypotrichosis is the clinical feature of paucity of hair arising congenitally or in early life with the presentation being that of the child whose hair is growing insufficiently. It is a hallmark finding of a diverse group of genodermatoses and sporadic disorders, presenting as either an isolated symptom or in association with ...
Neda So, Leona Yip, David Orchard
wiley   +1 more source

Mitochondrial Mutation Leads to Cardiomyocyte Hypertrophy by Disruption of Mitochondria‐Associated ER Membrane

Cell Proliferation, EarlyView.
Cardiomyocytes with high m.3243A>G burden exhibited hypertrophic phenotype. Mitochondria dysfunction occurred and tended to become round in cardiomyocytes with high m.3243A>G burden. Mitochondria‐associated ER membrane (MAM) was disrupted in cardiomyocytes with high m.3243A>G burden.
Miao Yu, Min Song, Manna Zhang, Shuangshuang Chen, Baoqiang Ni, Xuechun Li, Wei Lei, Zhenya Shen, Yong Fan, Jianyi Zhang, Shijun Hu   +10 more
wiley   +1 more source