Results 181 to 190 of about 117,203 (208)

Left Atrial Appendage Thrombus in Hypertrophic Cardiomyopathy With Atrial Fibrillation—Common and Resistant to Treatment

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Daniele Massera, Mark V. Sherrid
doaj   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

5G Cloud‐Enabled Telemedicine for Remote Management of Heart Failure Patients With Implantable Cardioverter‐Defibrillators: A Multicenter Open‐Label Randomized Controlled Trial

MedComm, Volume 7, Issue 10, October 2026.
Postoperative follow‐up for patients with implantable cardioverter‐defibrillators and cardiac resynchronization therapy defibrillators (ICD/CRT‐D) is often delayed in remote areas because of geographic barriers and limited healthcare resources, increasing the risk of adverse outcomes. The “Make Changes” study, was a prospective, multicenter, open‐label
Pan Li, Fayuan Fu, Yiding Qi, Xianxian Zhao, Yingyi Qin, Xinghua Shan, Jing Jiang, Guowei Wang, Jingjuan Huang, Bo Liu, Zhifu Guo, Zhongkai Wang   +11 more
wiley   +1 more source

Analysis of Whole Exome Sequencing Results of Type 2 Diabetic Pedigree

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
Mutations of EPHX3 gene rs760409070[c.778 G>A (p.Glu260Lys)] and FHOD1 gene rs142023201 [c.1493 A>G (p.Asn498Ser)] are likely contributing genetic factors to T2DM in this pedigree. Based on bioinformatic analysis, we hypothesize that these mutations may promote diabetes pathogenesis by reducing peripheral insulin sensitivity, impairing glucose uptake ...
Jie Chen, Jia‐Li Li, He‐Jia Yin, Wei‐Chang Guo, Hui‐Fang Li   +4 more
wiley   +1 more source

Cytogenetic and Molecular Findings in Hydrops‐Related Mirror Syndrome

Prenatal Diagnosis, Volume 46, Issue 11, Page 1752-1759, October 2026.
ABSTRACT Objective Mirror syndrome is a rare, life‐threatening condition in which maternal fluid overload mirrors fetal hydrops. Data on genetic findings in affected pregnancies are limited. We compared genetic diagnoses in hydrops cases with and without mirror syndrome.
Brian A. Burnett, Christian M. Parobek, Jessian L. Munoz, Lauren E. Westerfield, Kristi Poling, Cara Buskmiller, Amir A. Shamshirsaz, Roopali V. Donepudi, Ignatia B. Van den Veyver, Magdalena Sanz Cortes, Michael A. Belfort, Ahmed A. Nassr   +11 more
wiley   +1 more source

METTL14‐Mediated m6A Methylation Preserves Cardiomyocyte Homeostasis and Attenuates Progeria‐Associated Cardiac Remodeling

Aging Cell, Volume 25, Issue 10, October 2026.
Progerin accumulation downregulates the expression of m6A methyltransferases METTL3 and METTL14 in cardiac tissues, impairing m6A modification‐mediated regulation of target genes including Casq2, Ifna and Ifnb, leading to calcium signaling dysregulation and pro‐inflammatory activation in the aged heart.
Shixiao Wang, Jie Zhang, Ying Ao, Dan Rao, Cong Yu, Chenzhong Xu, Ming Wang, Mingying Li, Xin Huang, Jianfei Zhang, Rui Mei, Zhen Zhang, Jie Sun, Juanli Duan, Ying Sun, Zimei Wang, Wen Su, Baohua Liu   +17 more
wiley   +1 more source

Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study

Andrology, Volume 14, Issue 7, Page 2262-2273, October 2026.
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova, Nancy Babio, Cristina Valle‐Hita, María Fernández de la Puente, Alfonso Beltran‐Arasa, Miguel Cebrián‐Puig, Violeta Fambuena‐Perez, Iván García‐Serrano, Michelle M. Murphy, Jordi Salas‐Salvadó, Albert Salas‐Huetos   +10 more
wiley   +1 more source

Clinical and Genetic Profile of One Molecularly Confirmed and One Clinically Suspected Case of LZTR1 ‐Related Noonan Syndrome

Clinical Genetics, Volume 110, Issue 4, Page 502-507, October 2026.
This study illustrates the phenotypic variability of LZTR1‐related Noonan syndrome type 10 in two pediatric patients, including presentations without congenital heart defects. The findings emphasize the importance of whole‐exome sequencing and longitudinal re‐evaluation of variants of uncertain significance in achieving accurate diagnosis.
Karolina Skrzyńska, Barbara Kalina‐Faska, Ewa Błaszczyk, Aneta Gawlik‐Starzyk   +3 more
wiley   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy

Circulation, 2021
Daniel Bernstein, Alison Vander Roest, Kévin Contrepois   +2 more
exaly  

Mavacamten Favorably Impacts Cardiac Structure in Obstructive Hypertrophic Cardiomyopathy

Circulation, 2021
Neal K Lakdawala, Raymond Y Kwong, Andrew Wang   +2 more
exaly