Results 171 to 180 of about 55,948 (258)

Modified Tibial Plateau Levelling Osteotomy in a Cat With a Cranial Cruciate Ligament Rupture and a Concurrent Medial Patellar Luxation

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A 12‐year‐old castrated male Russian Blue cat presented with cranial cruciate ligament rupture and concurrent grade 3 medial patellar luxation. A modified tibial plateau‐levelling osteotomy (mTPLO) using an Arix‐vet plate with a 2‐mm offset was performed, simultaneously correcting cranial tibial thrust and patellar luxation in a single procedure.
Ji‐Hwan Pahk   +2 more
wiley   +1 more source

A Non‐Channel Function of CFTR: Attenuating Mitochondrial Oxidative Stress and Cardiomyocyte Senescence via Stabilization by USP45

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
USP45 stabilizes CFTR through deubiquitination, thereby activating PMCA, which inhibits calcium/chloride overload and mitochondrial oxidative stress in senescent cardiomyocytes, ultimately alleviating cardiomyocyte senescence. ABSTRACT Cardiomyocyte senescence drives cardiovascular disease, underscoring the need to define its molecular mechanisms.
Chun Chen   +10 more
wiley   +1 more source

Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
In children who want to play sports, is a cardiac evaluation necessary only for sudden cardiac death? ABSTRACT Objective Sudden deaths may occur in children and adolescents due to unexpected cardiac problems during sports. This study aimed to screen for abnormalities that may lead to future morbidity in addition to the risk of sudden death and to ...
Mehmet Öncül, Abdulgani Gülyüz
wiley   +1 more source

An Accessible Algorithm for the Quick and Precise Interpretation of Atrioventricular Blocks in Electrocardiograms

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
Interpretation of electrocardiograms (ECGs) using an algorithm can improve the detection and diagnosis of atrioventricular blocks in clinical practice. The proposed algorithm, with its high accuracy and structured approach, can help both experienced and less‐experienced healthcare professionals interpret ECGs with more precision, leading to early ...
Ali A. Ashkanani   +4 more
wiley   +1 more source

The role of fluvoxamine in the treatment of endotoxin‐induced acute heart injury

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 13, Page 3815-3828, July 2026.
Abstract Background and Purpose Cardiovascular diseases are among the most common health problems worldwide. Inflammation plays a critical role in the pathogenesis of various heart diseases. Lipopolysaccharides (LPS) trigger inflammatory mechanisms, leading to an inflammatory response.
Ilter Ilhan   +5 more
wiley   +1 more source

Non‐invasive pressure–volume loop analysis in left ventricular load manipulation

open access: yesClinical Physiology and Functional Imaging, Volume 46, Issue 4, July 2026.
Abstract Background Clinical monitoring of patients with heart failure or cardiomyopathy is facilitated by detailed assessment of cardiac loading conditions. Specifically, alterations in preload and afterload may unmask pathology through effects on ventricular pressure–volume (PV) relations. Therefore, the aim was to assess non‐invasive PV loops during
Karin Pola   +9 more
wiley   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3848-3864, July 2026.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki   +4 more
wiley   +1 more source

Myocardial Immune Niches in Homeostasis and Inflammation

open access: yesImmunological Reviews, Volume 340, Issue 1, July 2026.
ABSTRACT The heart functions as a circulatory pump that supplies blood throughout the body. The execution of this critical function depends on the interplay between cardiomyocytes and the supportive cellular infrastructure, generated by endothelial cells, fibroblasts and distinct immune cell populations.
Christian Perez‐Shibayama   +6 more
wiley   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang   +4 more
wiley   +1 more source

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