Results 11 to 20 of about 310,584 (195)

Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy

Circulation, 2021
Supplemental Digital Content is available in the text. Background: Hypertrophic cardiomyopathy (HCM) is a complex disease partly explained by the effects of individual gene variants on sarcomeric protein biomechanics. At the cellular level, HCM mutations
Sara Ranjbarvaziri, K. Kooiker, M. Ellenberger, G. Fajardo, Mingming Zhao, A. V. Vander Roest, R. A. Woldeyes, Tiffany T Koyano, R. Fong, Ning Ma, Lei Tian, G. Traber, F. Chan, J. Perrino, Sushma Reddy, Wah Chiu, Joseph C. Wu, Joseph Y. Woo, K. Ruppel, J. Spudich, M. Snyder, K. Contrepois, D. Bernstein   +22 more
semanticscholar   +1 more source

An overview of the current genetic and phenotypical selection strategies to reduce the prevalence of feline hypertrophic cardiomyopathy = Een overzicht van de huidige genetische en fenotypische selectiestrategieën tegen hypertrofe cardiomyopathie bij de kat [PDF]

, 2020
Hypertrophic cardiomyopathy (HCM) is a common and potentially lethal heart disease in cats. To reduce its prevalence, breeding cats are frequently screened on the basis of their phenotype or genotype.
Broeckx, Bart, Peelman, Luc, Schipper, Tom, Smets, Pascale   +3 more
core   +1 more source

Left Atrial Reservoir Strain-Based Left Ventricular Diastolic Function Grading and Incident Heart Failure in Hypertrophic Cardiomyopathy

Circulation Cardiovascular Imaging, 2022
Background: The echocardiographic assessment of left ventricular (LV) diastolic dysfunction (LVDD) in patients with hypertrophic cardiomyopathy is complex and not well-established.
Hyun-Jung Lee, Hyung‐Kwan Kim, T. Rhee, You-jung Choi, In-Chang Hwang, Y. Yoon, Jun‐Bean Park, Seung‐Pyo Lee, Yong‐Jin Kim, G. Cho   +9 more
semanticscholar   +1 more source

Circulating Biomarkers in Hypertrophic Cardiomyopathy

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2022
Hypertrophic cardiomyopathy is the most common genetic heart disease. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in diagnosis, directing treatment, and predicting outcomes.
Eldon Matthia, Michael L Setteducato, Mohammed Elzeneini, Nicholas Vernace, M. Salerno, C. Kramer, E. Keeley   +6 more
semanticscholar   +1 more source

Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy

European Heart Journal, 2021
Aims Childhood-onset hypertrophic cardiomyopathy (HCM) is far less common than adult-onset disease, thus natural history is not well characterized. We aim to describe the characteristics and outcomes of childhood-onset HCM.
N. Marston, Larry Han, I. Olivotto, S. Day, E. Ashley, M. Michels, A. Pereira, J. Ingles, C. Semsarian, D. Jacoby, S. Colan, J. Rossano, S. Wittekind, J. Ware, S. Saberi, A. Helms, Carolyn Y. Ho   +16 more
semanticscholar   +1 more source

Molecular Genetic Basis of Hypertrophic Cardiomyopathy.

Circulation Research, 2021
Hypertrophic cardiomyopathy (HCM) is a genetic disease of the myocardium characterized by a hypertrophic left ventricle with a preserved or increased ejection fraction.
A. Marian
semanticscholar   +1 more source

Perioperative Amiodarone to Prevent Atrial fibrillation after Septal Myectomy in obstrUctive hypeRtroPHic cardiomyopathy

ESC Heart Failure, 2021
Aims Amiodarone reduces the incidence of atrial fibrillation (AF) following coronary artery bypass surgery; however, the benefit of perioperative amiodarone in patients undergoing septal myectomy (SM) for obstructive hypertrophic cardiomyopathy (oHCM ...
Evan F. Shalen, Stephen B. Heitner, Lana Al‐Rashdan, Reyhaneh Akhavein, Miriam R. Elman, Katherine L. Fischer, Lucy Q. Lin, Meghan Mannello, Babak Nazer, Howard K. Song, Ahmad Masri   +10 more
doaj   +1 more source

Toward Replacing Late Gadolinium Enhancement With Artificial Intelligence Virtual Native Enhancement for Gadolinium-Free Cardiovascular Magnetic Resonance Tissue Characterization in Hypertrophic Cardiomyopathy

Circulation, 2021
Supplemental Digital Content is available in the text. Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging is the gold standard for noninvasive myocardial tissue characterization but requires intravenous contrast
Qiang Zhang, M. Burrage, E. Lukaschuk, M. Shanmuganathan, Iulia A. Popescu, C. Nikolaidou, Rebecca Mills, K. Werys, E. Hann, A. Barutcu, Suleyman D Polat, M. Salerno, M. Jerosch-Herold, R. Kwong, H. Watkins, C. Kramer, S. Neubauer, V. Ferreira, S. Piechnik   +18 more
semanticscholar   +1 more source

Clinical Outcomes in Patients With Nonobstructive, Labile, and Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundHypertrophic cardiomyopathy (HCM) is a common inherited cardiac disease characterized by varying degrees of left ventricular outflow tract obstruction. In a large cohort, we compare the outcomes among 3 different hemodynamic groups. Methods and
Dai‐Yin Lu, Iraklis Pozios, Bereketeab Haileselassie, Ioannis Ventoulis, Hongyun Liu, Lars L. Sorensen, Marco Canepa, Susan Phillip, M. Roselle Abraham, Theodore P. Abraham   +9 more
doaj   +1 more source

First-in-man application of Liwen RF™ ablation system in the treatment of drug-resistant hypertrophic obstructive cardiomyopathy

Frontiers in Cardiovascular Medicine, 2022
ObjectivesThis study sought to evaluate the clinical applicability of the Liwen Liu RF™ ablation system for percutaneous intramyocardial septal radiofrequency ablation (PIMSRA).BackgroundData on new cardiac radiofrequency ablation devices for the ...
Zihao Wang, Rong Zhao, Horst Sievert, Shengjun Ta, Jing Li, Stefan Bertog, Stefan Bertog, Kerstin Piayda, Mengyao Zhou, Changhui Lei, Xiaojuan Li, Jiani Liu, Bo Xu, Bo Feng, Rui Hu, Liwen Liu   +15 more
doaj   +1 more source