The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Serial Cardiovascular Magnetic Resonance Evolution of Late-Onset Female Danon Disease Initially Diagnosed as Hypertrophic Cardiomyopathy: A Case Report. [PDF]
Liu X, Liang S, Chen J, Chen Y.
europepmc +1 more source
Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma +5 more
wiley +1 more source
Prenatal Fetal Growth Restriction and Cardiomyopathy Associated With an Unbalanced der(15)t(7;15): A Case Report. [PDF]
Nagayasu Y +11 more
europepmc +1 more source
GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao +10 more
wiley +1 more source
Third-Space Entrapment of Methotrexate in Anthracycline-Induced Cardiomyopathy: The First Complete Case Trajectory From Toxicity to Rescue Failure. [PDF]
Mehta S, Rizvi SS, Mohamed S, Galvez C.
europepmc +1 more source
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan +3 more
wiley +1 more source
Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy. [PDF]
Wu Q +13 more
europepmc +1 more source
This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi +11 more
wiley +1 more source

