Results 61 to 70 of about 413,499 (385)

To unwind the biological knots: The DNA/RNA G‐quadruplex resolvase RHAU (DHX36) in development and disease

Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022
Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang, Jie Yao, Huijuan Yi, Xinyi Huang, Wukui Zhao, Zhongzhou Yang   +5 more
wiley   +1 more source

Incidence of Stress Cardiomyopathy During the Coronavirus Disease 2019 Pandemic

JAMA Network Open, 2020
Key Points Question Is psychological, social, and economic stress associated with coronavirus disease 2019 (COVID-19) associated with the incidence of stress cardiomyopathy?
Ahmad Jabri, A. Kalra, Ashish Kumar, A. Alameh, S. Adroja, H. Bashir, A. Nowacki, R. Shah, Shameer Khubber, Anmar Kanaa’n, David P. Hedrick, Khaled M. Sleik, N. Mehta, M. Chung, U. Khot, S. Kapadia, R. Puri, G. Reed   +17 more
semanticscholar   +1 more source

Inhibition of the NLRP3/IL‐1β axis protects against sepsis‐induced cardiomyopathy

Journal of Cachexia, Sarcopenia and Muscle, 2021
Septic cardiomyopathy worsens the prognosis of critically ill patients. Clinical data suggest that interleukin‐1β (IL‐1β), activated by the NLRP3 inflammasome, compromises cardiac function.
Katharina Busch, Melanie Kny, Nora Huang, T. Klassert, Magdalena Stock, Alexander Hahn, Sebastian Graeger, M. Todiras, S. Schmidt, B. Chamling, M. Willenbrock, Stefan Gross, Doreen Biedenweg, A. Heuser, C. Scheidereit, C. Butter, S. Felix, O. Otto, F. Luft, H. Slevogt, J. Fielitz   +20 more
semanticscholar   +1 more source

Cardiomyocyte-targeted and 17β-estradiol-loaded acoustic nanoprobes as a theranostic platform for cardiac hypertrophy

Journal of Nanobiotechnology, 2018
Background Theranostic perfluorocarbon nanoprobes have recently attracted attention due to their fascinating versatility in integrating diagnostics and therapeutics into a single system.
Xueli Zhao, Wen Luo, Jing Hu, Lei Zuo, Jing Wang, Rui Hu, Bo Wang, Lei Xu, Jing Li, Meng Wu, Pan Li, Liwen Liu   +11 more
doaj   +1 more source

Acute Left Ventricular Ballooning: Tools to Differentiate Hypertrophic Cardiomyopathy with Outflow Obstruction from Neurohumoral Takotsubo Syndrome

Reviews in Cardiovascular Medicine, 2023
Despite considerable interest in the syndrome of acute left ventricular (LV) ballooning, its pathophysiology has remained ill-defined. In this review, we explore observational data describing two etiologies of acute LV ballooning: neurohumoral classic ...
Arushi Singh, Louai Razzouk, Daniele Massera, Mark V. Sherrid   +3 more
doaj   +1 more source

Sepsis-Induced Cardiomyopathy: a Comprehensive Review

Current Cardiology Reports, 2020
Purpose of Review To briefly review epidemiology and pathophysiology of SICM and provide a more extensive review of the data on diagnostic and management strategies.
M. L’Heureux, Michael Sternberg, L. Brath, Jeremy S. Turlington, M. Kashiouris   +4 more
semanticscholar   +1 more source

Cirrhotic cardiomyopathy [PDF]

Orphanet Journal of Rare Diseases, 2007
Abstract Cirrhotic cardiomyopathy is the term used to describe a constellation of features indicative of abnormal heart structure and function in patients with cirrhosis. These include systolic and diastolic dysfunction, electrophysiological changes, and macroscopic and microscopic structural changes.
Fouad Tamer R, Baik Soon, Lee Samuel S
openaire   +3 more sources

Comprehensive Risk Management in Arrhythmogenic Cardiomyopathy Associated With Autosomal Dominant Carvajal Syndrome

JACC: Case Reports, 2020
In a 37-year-old cardiac arrest survivor with autosomal dominant Carvajal syndrome and arrhythmogenic cardiomyopathy, a desmoplakin mutation was identified.
Maria Grazia De Gregorio, MD, Francesca Girolami, BS, Benedetta Tomberli, MD, Guendalina Rossi, MD, Alessia Tomberli, RN, Katia Baldini, RN, Iacopo Olivotto, MD   +6 more
doaj  

Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes

JAMA cardiology, 2021
Key Points Question In patients diagnosed with atrial fibrillation before 66 years of age, what is the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes? Findings In this cohort study,
Z. Yoneda, K. Anderson, Joseph A. Quintana, M. O’Neill, Richard A. Sims, A. Glazer, C. Shaffer, Diane M. Crawford, T. Stricker, Fei Ye, Q. Wells, L. Stevenson, G. Michaud, D. Darbar, S. Lubitz, P. Ellinor, D. Roden, M. B. Shoemaker   +17 more
semanticscholar   +1 more source

Infiltrative Cardiomyopathies [PDF]

Clinical Medicine Insights: Cardiology, 2015
Infiltrative cardiomyopathies can result from a wide spectrum of both inherited and acquired conditions with varying systemic manifestations. They portend an adverse prognosis, with only a few exceptions (ie, glycogen storage disease), where early diagnosis can result in potentially curative treatment.
David Bejar, Paolo C. Colombo, Farhana Latif, Melana Yuzefpolskaya   +3 more
openaire   +4 more sources