Results 31 to 40 of about 10,048 (159)

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

Del Nido cardioplegia versus cold blood cardioplegia in adult cardiac surgery: a meta-analysis of randomized clinical trials

Journal of Cardiothoracic Surgery
Objective Systematic evaluation of the safety of del Nido cardioplegia compared to cold blood cardioplegia in adult cardiac surgery. Methods We systematically searched PubMed, EMbase, The Cochrane Library and ClinicalTrials.gov for randomized clinical ...
Congcong Li, Haiyan Xiang, Heng Yang, Wu Liu, Wanqi Lan, Chao Luo, Shuangjian Han, Yongqin Li, Yanhua Tang   +8 more
doaj   +1 more source

A comparative study between custodiol and warm blood cardioplegia in coronary artery bypass graft operation with poor left ventricular function

Journal of Medicine in Scientific Research, 2019
Background Cardioplegia is responsible for myocardial protection during open heart surgery. Cardioplegia was first presented as an agent for hypothermic hyperkalemic arrest.
Ahmed S Ali, Samir Ahmed Ataa, Hassan Mohamed Moftahb, Mohamed Ali El Ghanamb, Moustafa Gamal Eldin Moustafab   +4 more
doaj   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

73. Custodiol versus blood cardioplegia in pediatric cardiac surgery

Journal of the Saudi Heart Association, 2015
Cardioplegia is a solution used to arrest and protect the heart during open cardiac repair with the use of cardiopulmonary-bypass. Two types of cardioplegia were evaluated.
Ebtehal Qulaissi, Osman Al-Radi, Rajab Debes   +2 more
doaj   +1 more source

Cold blood cardioplegia

The Journal of Thoracic and Cardiovascular Surgery, 1979
The technique of myocardial protection by means of a cardioplegic solution consisting of cold blood (10 degrees C) with potassium (30 mEq. per liter) is described. A disposable cooling coil is used and a separate pump head for coronary perfusion is avoided.
H, Laks, H B, Barner, G, Kaiser
openaire   +2 more sources

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar, Triveni Kodi, Adarsh Gopinathan, Bharath Harohalli Byregowda, Krishnadas Nandakumar, Anoop Kishore   +5 more
wiley   +1 more source

Successful Management of Contained Left Ventricular Free Wall Rupture Associated With Myocardial Infarction

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Left ventricular free wall rupture (LVFWR) is a deadly mechanical complication that, in approximately 2%–6% of patients, arises following acute myocardial infarction (MI). It could occur in different situations, ranging from several minutes to over one month following MI, usually among patients with risk factors.
Mojtaba Mansouri, Fatemeh Jadidi, Abbas Toughanipour, Gholamreza Massoumi   +3 more
wiley   +1 more source

Enhancing Surgical Decision‐Making for Infected Cardiac Device Lead Removal With 18F‐FDG PET/CT: A Case Study and Literature Analysis

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Residual implantable cardiac electronic device (ICED) leads pose a significant infection risk, necessitating a multimodal diagnostic and therapeutic approach. This case highlights the critical role of PET/CT imaging in guiding surgical decision‐making, particularly in cases of chronic infections with embedded or fractured lead fragments. While
Said Khallikane, Reda Mounir, Noureddine Atmani, Abdessamad Abdou, Ayoub Belhadj, Younes Aissaoui   +5 more
wiley   +1 more source

Adding Blood to St Thomas Solution Does Not Improve Mortality in Pediatric Cardiac Surgery; A Meta-analysis of a Homogenous Population

The Annals of African Surgery, 2020
Background: Cardioplegia is the gold standard for providing ideal operating conditions while effecting myocardial protection. Some studies suggest that adding blood to St Thomas cardioplegia solution improves efficacy; this is generally accepted as true.
Mark Awori, Nikita Mehta, Naomi Kebba, Enoch Makori   +3 more
doaj