Pharmacological Research, 1998 In open heart surgery it is very important to protect the heart during the ischaemic period in terms of mortality and morbidity. Many different cardioplegic solutions are in clinical use without being tested experimentally.
Koseoglu, S, Ozuner, Z, Suzer, O
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Comparative Effects of HTK and St. Thomas Cardioplegia on Myocardial Outcomes and Sodium Balance in Pediatric Tetralogy of Fallot Surgery [PDF]
Journal of Multidisciplinary HealthcareLi-Jun Liang,1 Zhi-Lan Ding,1 Li-Fen Zhang,1 Cai-Xia Liu,1 Hong-Wei Xi,2 Jin-Ming Yang1 1Department of Cardiothoracic Surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, Taiyuan, Shanxi Province, 030025, People’s Republic of China ...
Liang LJ +5 more
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Evaluating a Novel Cell-Free Preservation Solution for Human Cardiomyocyte Protection: A Proof-of-Concept Study. [PDF]
Biomed Res IntBackground Heart transplantation remains the definitive therapy for end‐stage heart failure; however, its clinical impact is constrained by donor availability and preservation‐associated injury. Static cold storage (SCS) with cardioplegic solutions such as Custodiol is the current clinical standard of care, yet extended cold ischemia markedly increases
Beckers C +10 more
europepmc +2 more sources
Pharmacological Research, 1997 Cardiac transplantation is a prominent development in the treatment of patients with severe cardiac diseases. If it is not possible to transplant the heart immediately after removing it from the donor, procedures for preparing, protecting, storing and ...
Dildar Konukoğlu
exaly +2 more sources
How different cardioplegic solutions influence genes expression and cytokine response in an immature rat heart model of ischemia/reperfusion? [PDF]
PLoS ONEIntroductionThe use of cardioplegia not only achieves cardiac arrest but also minimizes ischemic/reperfusion (I/R) injury, potentially improving short- or long-term outcomes.
Arslan Mamedov +9 more
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General Pharmacology, 1999 1. Cardioplegic solutions provide the opportunity to operate on a nonbeating heart and to protect the heart against ischemic injury during cardiac surgery.
Koseoglu, S, Han, G, Suzer, O
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Cardioplegic Solution Provides Myocardial Protection via Activation of NRF2
, 2020 Open heart surgery is often an unavoidable procedure for treatment of cardiovascular disease. Myocardial Ischemia-Reperfusion Injury (MIRI) can occur as a result of cardiopulmonary bypass which is required in open heart surgery.
Diao, Hongting
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Histidine-tryptophan-ketoglutarate solution decreases mortality and morbidity in high-risk patients with severe pulmonary arterial hypertension associated with complex congenital heart disease: an 11-year experience from a single institution [PDF]
Brazilian Journal of Medical and Biological Research, 2016 Cardioplegic reperfusion during a long term ischemic period interrupts cardiac surgery and also increases cellular edema due to repeated solution administration.
X.W. Li +10 more
doaj +3 more sources
Theoretical and Practical Aspects in the Use of Bretschneider Cardioplegia
Journal of Cardiovascular Development and Disease, 2022 The race for an ideal cardioplegic solution has remained enthusiastic since the beginning of the modern cardiac surgery era. The Bretschneider solution, belonging to the “intracellular cardioplegic” group, is safe and practical in myocardial protection ...
Claudiu Ghiragosian +8 more
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Specific parameters of operation of the minimized system for cardioplegia in children. Bench test
Вестник анестезиологии и реаниматологии, 2020 It is very important to observe all the parameters of cardioplegia when protecting myocardium during cardiac surgery. To perform this task, it is necessary to have clear understanding of properties of the elements of the extracorporeal circuit of ...
A. B. Naumov +6 more
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