Results 61 to 70 of about 3,395,761 (154)

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

A novel survival model of cardioplegic arrest and cardiopulmonary bypass in rats: a methodology paper

Journal of Cardiothoracic Surgery, 2008
Background Given the growing population of cardiac surgery patients with impaired preoperative cardiac function and rapidly expanding surgical techniques, continued efforts to improve myocardial protection strategies are warranted.
Podgoreanu Mihai V, Yoshitani Kenji, de Lange Fellery, Grocott Hilary P, Mackensen G Burkhard   +4 more
doaj   +1 more source

A Rare Case of Anterior Papillary Muscle Rupture Following Acute Non‐ST Elevation Myocardial Infarction

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Sudden hemodynamic deterioration after myocardial infarction should prompt immediate evaluation for papillary muscle rupture, even in the absence of a murmur or large‐vessel occlusion. Acute severe mitral regurgitation from papillary muscle rupture may mimic recurrent ischemia, and early echocardiography with prompt surgical intervention can ...
Biyas Thapa, Somee Rauniyar, Pratiksha Paudel   +2 more
wiley   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

British Journal of Pharmacology, Volume 183, Issue 5, Page 1030-1047, March 2026.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero, Sarah Torp Yttergren, Max Hahn, Marie Biviano Rosenkilde, Ditte Marie Jensen, Michael Christensen, Louise Thisted, Heidi Lindgreen Holmberg, Geoffrey Teixeira, Tor Biering‐Sørensen, Casper Gravesen Salinas, Urmas Roostalu   +11 more
wiley   +1 more source

Supplemental l-arginine during cardioplegic arrest and reperfusion avoids regional postischemic injury [PDF]

, 1995
Unenhanced hypothermic cardioplegia does not prevent postischemic endothelial and contractile dysfunction in hearts subjected to antecedent regional or global ischemia.
Hammon, John W., Vinten-Johansen, J., Sato, Hiroki, Williams, Mark W., McGee, D.Scott, Zhao, Zhi-Qing   +5 more
core   +1 more source

Myocardial Protection in Combined Mitral-Aortic-Tricuspid Valve Diseases Correction under Cardiopulmonary Bypass

Український журнал серцево-судинної хірургії
The aim. To determine the optimal option for administering cardioplegic solution for myocardial protection in the correction of combined mitral-aortic-tricuspid valve diseases (CMAT) under cardiopulmonary bypass. Materials and methods. We analyzed the
Oleksii M. Gurtovenko, Volodymyr V. Popov, Andriy P. Mazur, Oleksandr O. Bolshak   +3 more
doaj   +1 more source

Nonvalvular Papillary Fibroelastoma of the Left Ventricle: A Case Report and Review of the Literature

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Papillary fibroelastoma (PFE) is a benign primary cardiac tumor that most commonly arises from valvular endocardium, whereas nonvalvular involvement, particularly within the left ventricle, is rare. Despite benign histology, PFEs are clinically relevant due to mobility and embolic risk.
Aibek E. Mirrakhimov, Satabdi Datta Choudhury   +1 more
wiley   +1 more source

Contained Rupture of a Saphenous Vein Graft Pseudoaneurysm Following Coronary Artery Bypass Grafting

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Saphenous vein graft (SVG) pseudoaneurysms are a rare cause of late graft failure with potentially lethal consequences if left untreated. We present the case of a patient who underwent multivessel coronary artery bypass grafting more than 10 years earlier and presented with chest pain.
Harry Ramcharran, Mahbub Jamil, Joseph Petro, Zhandong Zhou, Satabdi Datta Choudhury   +4 more
wiley   +1 more source

Myocardial Protective Effects of Nicardipine Hydrocloride (Perdipine) in Glucose Potassium Cardioplegic Solution on Isolated Rat Heart [PDF]

, 1985
The effect on myocardial protection against ischemic damage by addition of the Ca antagonist perdipine (nicardipine) at 0.25mg/L, and 0.5mg/L, to cardioplegic solution on isolated rat heart was assessed by hemodynamic studies, the time required to ...
Kawabe, Hideaki, Hideaki Kawabe
core