Results 11 to 20 of about 7,955,722 (163)

Comparison of Clinical Outcomes of Two Different Cardioplegic Solutions in Patients Undergoing Coronary Artery Bypass Graft Surgery; A randomize clinical trial [PDF]

Advanced Biomedical Research
Background: Usually, manual cardioplegic solutions with low magnesium and lidocaine, and corporate solutions with high magnesium and procaine, are the only common solutions used to induce cardiac arrest during coronary artery bypass graft (CABG) surgery.
Alireza Hosseini, Mehran Shahzamani, Asieh Maghami-Mehr, Farzin Khosravi, Nafiseh Emadi   +4 more
doaj   +2 more sources

How different cardioplegic solutions influence genes expression and cytokine response in an immature rat heart model of ischemia/reperfusion? [PDF]

PLoS ONE
IntroductionThe use of cardioplegia not only achieves cardiac arrest but also minimizes ischemic/reperfusion (I/R) injury, potentially improving short- or long-term outcomes.
Arslan Mamedov, Dovydas Gečys, Povilas Jakuška, Rimantas Treinys, Deimantė Narauskaitė, Serik Aitaliyev, Eglė Rumbinaitė, Dainius Karčiauskas, Rimantas Benetis, Edgaras Stankevičius   +9 more
doaj   +3 more sources

The Potential Role of MicroRNAs as Cardioprotective Agents During Cardioplegia: A Preliminary Qualitative Systematic Review [PDF]

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Recent advancements in gene expression studies have shed light on the role of non‐coding RNAs in negatively regulating mRNA and inhibiting mRNA translation. Given the significant impact of miRNAs on cardiovascular function, our review aims to comprehensively explore their contribution to mitigating heart injury and their ...
Maryam Baniani, Ali Dabbagh, Pourya Shokri, Firoozeh Madadi   +3 more
wiley   +2 more sources

Comparable renal effects of histidine-tryptophan-ketoglutarate and DelNido cardioplegia in a porcine model of cardiac arrest [PDF]

Renal Failure
Acute kidney injury (AKI) is a serious complication following on-pump cardiac surgery. Choosing the cardioplegic solution with the most appropriate myocardial protection and lowest grade of AKI could improve patient outcome.
Maja-Theresa Dieterlen, Jagdip Kang, Paul Schütte, Kristin Klaeske, Susann Oßmann, Philipp Kiefer, Marcel Vollroth, Michael A. Borger, Alexandro Hoyer   +8 more
doaj   +2 more sources

Lidocaine and Pinacidil Added to Blood versus Crystalloid Cardioplegic Solutions: Study in Isolated Hearts [PDF]

Brazilian Journal of Cardiovascular Surgery, 2018
Objective: The present study aimed the functional recovery evaluation after long term of cardiac arrest induced by Custodiol (crystalloid-based) versus del Nido (blood-based) solutions, both added lidocaine and pinacidil as cardioplegic agents ...
Helison Pereira do Carmo, Karla Reichert, Daniela Diógenes de Carvalho, Lindemberg da Mota Silveira-Filho, Karlos Vilarinho, Pedro Oliveira, Orlando Petrucci   +6 more
doaj   +2 more sources

Evaluating a Novel Cell‐Free Preservation Solution for Human Cardiomyocyte Protection: A Proof‐of‐Concept Study [PDF]

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Heart transplantation remains the definitive therapy for end‐stage heart failure; however, its clinical impact is constrained by donor availability and preservation‐associated injury. Static cold storage (SCS) with cardioplegic solutions such as Custodiol is the current clinical standard of care, yet extended cold ischemia markedly increases
Christian Beckers, Sandra Kraemer, Alexander Theißen, Merlin Kunze, Josefin Soppert, Leon Schurgers, Rogier Veltrop, Benedict Doorschodt, René H. Tolba, Jan Larmann, Christian Bleilevens, Poorani Gurumallesh Prabu   +11 more
wiley   +2 more sources

Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation [PDF]

JHLT Open
Introduction: Donation after circulatory death (DCD) has re-emerged as a means of expanding the donor heart pool. Current clinical practice relies mainly on direct procurement followed by normothermic machine perfusion or on thoraco-abdominal ...
K. Vandendriessche, J. Brouckaert, K. Van de Voorde, F. Gaublomme, K. Degezelle, J. Van Cleemput, A. Wallinder, F. Rega   +7 more
doaj   +2 more sources

Molecular and Cellular Mechanisms of Cardioplegic Protection in Surgical Myocardial Revascularization [PDF]

Cells
Coronary artery bypass grafting (CABG) remains the gold standard for patients with advanced multivessel coronary artery disease. Optimal myocardial protection versus ischemia during reversible and controlled cardiac arrest is a cornerstone of successful ...
Dejan M. Lazović, Milica Karadžić Kočica, Dragan Ivanišević, Vojkan Aleksić, Mladen J. Kočica, Danko Grujić, Jovana M. Mihajlović, Dragan Cvetković, Stefan A. Juričić   +8 more
doaj   +2 more sources

Comparative Effects of HTK and St. Thomas Cardioplegia on Myocardial Outcomes and Sodium Balance in Pediatric Tetralogy of Fallot Surgery [PDF]

Journal of Multidisciplinary Healthcare
Li-Jun Liang,1 Zhi-Lan Ding,1 Li-Fen Zhang,1 Cai-Xia Liu,1 Hong-Wei Xi,2 Jin-Ming Yang1 1Department of Cardiothoracic Surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, Taiyuan, Shanxi Province, 030025, People’s Republic of China ...
Liang LJ, Ding ZL, Zhang LF, Liu CX, Xi HW, Yang JM   +5 more
doaj   +2 more sources

Comment on "Lidocaine and pinacidil added to blood versus crystalloid cardioplegic solutions: study in isolated hearts" [PDF]

Brazilian Journal of Cardiovascular Surgery, 2018
Claus J. Preusse
doaj   +2 more sources