Results 231 to 240 of about 3,870 (268)

The Optimal Potassium Concentration in Cardioplegic Solutions

The Annals of Thoracic Surgery, 1981
High-energy phosphates provide a sensitive index of myocardial preservation. This experiment was designed to use this index in order to assess the efficacy of various potassium concentrations in a crystalloid cardioplegic solution in protecting the myocardium during hypothermic ischemic arrest.
John H. Rousou, Richard M. Engelman, Stanley Lemeshow, William A. Dobbs   +3 more
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Vascular effects of potassium cardioplegic solutions

General Pharmacology: The Vascular System, 1983
Experiments have been performed on isolated human umbilical and sheep coronary arteries, studying the effects of increasing potassium concentration in steps from 10 to 160 mM. Comparative studies were also done on rat-heart papillary-muscle preparations. The results revealed a dose-dependent increase in smooth muscle tone of the blood vessels.
Shuhaiber Hj, Olav Thulesius, A.M. Yousof, Abdullah Elkhawad, J.S. Juggi   +4 more
openaire   +3 more sources

Oxygenation of cardioplegic solutions: A note of caution

The Annals of Thoracic Surgery, 1991
The merits of oxygenated crystalloid cardioplegic solutions have been well established in experimental animals. The positive effects of oxygenation of Plasmalyte B (Sabax Ltd) and St. Thomas Hospital solution (Plegisol) were achieved by gassing with 95% O2/5% CO2 and 100% O2, respectively.
Amanda Lochner, André Coetzee, Llewelyn Lloyd, Wim Brits   +3 more
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Regional Myocardial Perfusion of Cardioplegic Solutions

The Annals of Thoracic Surgery, 1987
We compared the regional myocardial perfusion of blood cardioplegic solution (BCP) and crystalloid cardioplegic solution (CCP) in 14 mongrel dogs. Cardiopulmonary bypass was established at 28 degrees C, and a hydraulic occluder was placed around the proximal left anterior descending (LAD) coronary artery. In group 1 (N = 7) collateral coronary arteries
Haiduc Nj, Kenneth P. Lyons, John Eugene, Mark G. Kowall, Richard A. Ott, Cherylee W.J. Chang, Vincent L. Gelezunas   +6 more
openaire   +3 more sources

Is Cold, Cardioplegic Solution Harmful to the Lungs?

Scandinavian Journal of Thoracic and Cardiovascular Surgery, 1989
The effects of pulmonary flush with cold cardioplegic solution were investigated in 55 patients undergoing coronary artery bypass grafting. Extracorporeal circulation with bicaval cannulation was used in all cases, and single-dose cardioplegic solution was injected into the aortic root.
Eivind Øvrum, Michel Abdelnoor, Harald Lindberg, Einfrid Åm Holen, Karleif Vatne   +4 more
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Is potassium a necessary component of cardioplegic solutions?

Journal of Surgical Research, 1980
Abstract Potassium-treated hearts were more completely arrested, usually did not require defibrillation, and had slightly less impairment of left ventricular contractility than those treated with hypothermia alone. There was more reactive hyperemia in non-potassium-treated hearts suggesting a greater oxygen debt. There were no significant differences
Kit V. Arom, Kit V. Arom, John G. Fewel, John G. Fewel, John J. Ghidoni, John J. Ghidoni, J.Kent Trinkle, J.Kent Trinkle, Frederick L. Grover, Frederick L. Grover   +9 more
openaire   +3 more sources

Pediatric myocardial protection: a cardioplegic strategy is the “solution” [PDF]

Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual, 2004
This article describes the experimental infrastructure and subsequent successful clinical application of a comprehensive cardioplegic strategy that limits intraoperative injury and improves postoperative outcomes in pediatric patients. The infant heart is at high risk of damage from poor protection as a result of preoperative hypertrophy, cyanosis, and
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Maximal oxygenation of dilute blood Cardioplegic solution

The Annals of Thoracic Surgery, 1987
The content of dissolved O2 (the major source of O2 for the myocardium) of dilute blood cardioplegic solution (dBCS) varied widely when oxygenated at 4 degrees C by surface flow of O2 in a Bentley BCR-3500 cardiotomy reservoir. We have modified the system to consistently deliver maximally oxygenated dBCS to the heart.
Dennis D. O'Keefe, Alvin G. Denenberg, Gillian A. Geffin, William G. Hendren, Willard M. Daggett, Tim R. Love   +5 more
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Preparation of Oxygenated Cold Crystalloid Cardioplegic Solution

The Annals of Thoracic Surgery, 1986
The value of oxygenated, aqueous, cold cardioplegic solutions is being evaluated at several centers. The theoretical advantages of such a solution are counterbalanced in part by the complexity and expense of the preparation and delivery systems that have been used.
Gideon Merin, Noel H. Fishman
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Comparison of crystalloid and sanguineous cardioplegic solutions in the dog

American Journal of Veterinary Research, 1985
SUMMARY Myocardial protection provided by 2 types of cold cardioplegic solution and by cold saline solution was compared experimentally in dogs on cardiopulmonary bypass. Techniques and solutions used simulated clinical conditions. Serial biopsies of myocardium were assayed for adenosine triphosphate, adenosine diphosphate, and adenosine monophosphate.
C J, Spackman, D D, Caywood, P G, Gannon, R A, Irmiter, C F, Louis   +4 more
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