Results 1 to 10 of about 550,814 (265)

Combined analysis of single-cell and bulk transcriptome sequencing data identifies critical glycolysis genes in idiopathic pulmonary arterial hypertension

Journal of Translational Medicine
Background Abnormal glycolytic metabolism plays a significant role in pulmonary vascular remodeling in idiopathic pulmonary arterial hypertension (IPAH), yet the specific mechanisms remain unclear.
Xuan Gao, Youli Fan, Guijia Wang, Jiangjiang Xu, Runwei Deng, Jiangwei Song, Binfeng Sun, Yongbing Wang, Zixuan Wu, Ruyi Jia, Jing Huang, Huiyu He, Lei Gao, Yihao Zhang, Na Sun, Bingxiang Wu   +15 more
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A Concomitant Cancer Diagnosis Is Associated With Poor Cardiovascular Outcomes Among Acute Myocardial Infarction Patients

Frontiers in Cardiovascular Medicine, 2022
Background and AimsWith the increasing coexistence of cardiovascular disease and cancer in contemporary clinical practice, studies on the outcomes in acute myocardial infarction (AMI) patients with cancer has not been systematically investigated.
Xiang Peng, Xiang Peng, Zhuozhong Wang, Zhuozhong Wang, Muhua Cao, Muhua Cao, Yuqi Zheng, Yuqi Zheng, Ya'nan Tian, Ya'nan Tian, Li Yu, Li Yu, Wenjun Ni, Wenjun Ni, Shanjie Wang, Shanjie Wang, Zhifeng Qin, Zhifeng Qin, Suhong Zhao, Suhong Zhao, Jinwei Tian, Jinwei Tian, Bo Yu, Bo Yu   +23 more
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Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis

Advanced Science
Delayed neutrophil clearance after myocardial infarction (MI) significantly disrupts the myocardial microenvironment, but the underlying mechanisms remain unclear.
Zeng Wang, Lai Wei, Mingyang Wang, Shanjie Wang, Lili Xiu, Jiaxiang Sun, Rongzhe Lu, Yige Liu, Jiaxin Wang, Fengyi Liu, Weike Liu, Bo Yu, Yong Sun, Xueqin Gao, Shaohong Fang   +14 more
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Revisiting an old relationship: the causal associations of the ApoB/ApoA1 ratio with cardiometabolic diseases and relative risk factors—a mendelian randomization analysis

Cardiovascular Diabetology
Background It has been confirmed that the ApoB/ApoA1 ratio is closely associated with the incidence of cardiometabolic diseases (CMD). However, due to uncontrolled confounding factors in observational studies, the causal relationship of this association ...
Chao Fu, Dongbo Liu, Qi Liu, Xuedong Wang, Xiaoxue Ma, Hong Pan, Shi Feng, Zhao Sun, Weishen Qiao, Mengyue Yang, Shuang Gao, Hongyu Ding, Xingtao Huang, Jingbo Hou   +13 more
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Risk of End-Stage Kidney Disease and Topiramate Use

Kidney International Reports
Introduction: Topiramate is widely used for migraine prevention but has pleiotropic effects on renal sodium reabsorption and inflammation. Whether these effects could be associated with lower risk of end-stage kidney disease (ESKD) and cardiovascular ...
Jean-Michel Halimi, Valentin Maisons, Jean-Baptiste de Fréminville, Sébastien Roger, Arnaud Bisson, Stéphanie Chadet, Laurent Fauchier   +6 more
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Association between triglyceride levels and hypertension in patients with coronary artery disease undergoing percutaneous coronary intervention: a retrospective cross-sectional study

Frontiers in Cardiovascular Medicine
BackgroundThis study aimed to investigate the association between serum triglyceride (TG) levels and the presence of hypertension in patients with coronary artery disease (CAD) and hypertension undergoing percutaneous coronary intervention (PCI ...
Zhanqun Gao, Zhanqun Gao, Zhanqun Gao, Yubo Gao, Yubo Gao, Chao Fang, Chao Fang, Chen Zhao, Chen Zhao, Dirui Zhang, Dirui Zhang, Wei Hao, Wei Hao, Haibo Jia, Haibo Jia, Sining Hu, Sining Hu, Bo Yu, Bo Yu   +18 more
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ESKD, Major Cardiovascular Events, and Death Associated With Systemic Inflammation

Kidney International Reports
Introduction: Systemic inflammation may play a role in the progression of chronic kidney disease (CKD) and in the development of major cardiovascular events (MACE).
Jean-Michel Halimi, Valentin Maisons, Jean-Baptiste de Fréminville, Sébastien Roger, Arnaud Bisson, Stéphanie Chadet, Laurent Fauchier   +6 more
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Psychological consequences of functional sequelae after rectal cancer treatment: a narrative review

Discover Psychology
Purpose Rectal cancer treatment relies on multimodal approaches including surgery, radiotherapy, and chemotherapy, which are frequently associated with persistent functional sequelae such as bowel dysfunction, stoma formation, and sexual or urinary ...
Nicolas Michot, Eugenie Roussel, Urs Giger-Pabst, Amine Souadka, Sebastien Roger, Robert Courtois, Mehdi Ouaissi   +6 more
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METABOLIC AND BEHAVIORAL EFFECTS OF KETOGENIC AND NON-KETOGENIC LOW-CARBOHYDRATE DIETS

IBRO Neuroscience Reports, 2023
Ilya Smolensky, Kilian Zajac-Bakri, Catherine Brégère, Raphael Guzman, Dragos Inta   +4 more
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CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage

Acta Neuropathologica Communications, 2018
The central nervous system (CNS) contains several types of immune cells located in specific anatomic compartments. Macrophages reside at the CNS borders surrounding the brain vessels, in leptomeningeal spaces and the choroid plexus, where they interact ...
Jordi Pedragosa, Angélica Salas-Perdomo, Mattia Gallizioli, Roger Cugota, Francesc Miró-Mur, Ferran Briansó, Carles Justicia, Fernando Pérez-Asensio, Leonardo Marquez-Kisinousky, Xabier Urra, Anna Gieryng, Bozena Kaminska, Angel Chamorro, Anna M. Planas   +13 more
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