Results 21 to 30 of about 909,718 (306)

C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

Frontiers in Pharmacology, 2021
Hyperglycemia-induced endothelial cell senescence has been widely reported to be involved in the pathogenesis of type 2 diabetes mellitus‒accelerated atherosclerosis.
Gang Wang, Gang Wang, Baihe Han, Baihe Han, Ruoxi Zhang, Qi Liu, Qi Liu, Xuedong Wang, Xuedong Wang, Xingtao Huang, Xingtao Huang, Dandan Liu, Dandan Liu, Weishen Qiao, Weishen Qiao, Mengyue Yang, Mengyue Yang, Xing Luo, Xing Luo, Jingbo Hou, Jingbo Hou, Bo Yu, Bo Yu   +22 more
doaj   +1 more source

Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia

Journal of Neuroinflammation, 2020
Background Recent findings describe microglia as modulators of neurogenesis in the subventricular zone (SVZ). SVZ microglia in the adult rat are thought to adopt a neurotrophic phenotype after ischemic stroke.
Urs Fisch, Catherine Brégère, Florian Geier, Laurie Chicha, Raphael Guzman   +4 more
doaj   +1 more source

Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI)

BMC Cardiovascular Disorders, 2022
Background Calcified plaque is thought to adversely impact outcomes after percutaneous coronary intervention (PCI). This study sought to evaluate the impact of nodular calcification in patients with acute coronary syndrome treated with primary ...
Abigail Demuyakor, Sining Hu, Ekaterina Koniaeva, Minghao Liu, Ziqian Weng, Chen Zhao, Xue Feng, Luping He, Yishuo Xu, Ming Zeng, Wei Meng, Yanli Sun, Boling Yi, Zhanqun Gao, Yuhan Qin, Haibo Jia, Gary S. Mintz, Bo Yu   +17 more
doaj   +1 more source

Relationship between non-culprit lesion plaque characteristics changes and in-stent neoatherosclerosis formation: 1-year follow-up optical coherence tomography study

Reviews in Cardiovascular Medicine, 2021
The relationship between the in-stent neoatherosclerosis (ISNA) formation and the plaque’s characteristic changes in the non-culprit lesion is unclear.
Lei Xing, Yongpeng Zou, Chao Fu, Xiaoying Fan, Xuedong Wang, Qi Liu, Mengyue Yang, Dandan Liu, Linxing Feng, Jingbo Hou, Xingtao Huang   +10 more
doaj   +1 more source

Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]

, 2009
Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed, Camara, Amadou K.S., Chen, Qun, Heisner, James S., Lesnefsky, Edward J., Stowe, David F.   +5 more
core   +2 more sources

Mesenteric Ischemia [PDF]

Seminars in Interventional Radiology, 2009
Mesenteric ischemia is classified as either acute or chronic. The former is a life-threatening emergency in which a sudden reduction in intestinal blood flow may ultimately result in bowel infarction. The most common causes are arterial embolism, arterial thrombosis, nonocclusive mesenteric ischemia, and mesenteric venous thrombosis.
openaire   +2 more sources

Non-culprit plaque characteristics in acute coronary syndrome patients with raised hemoglobinA1c: an intravascular optical coherence tomography study

Cardiovascular Diabetology, 2018
Background Raised hemoglobinA1c (HbA1c) is an indicator of pre-diabetes, which is associated with increased risk of coronary artery disease. However, the detailed morphological characteristics of non-culprit plaques in acute coronary syndrome (ACS ...
Shaotao Zhang, Jiannan Dai, Haibo Jia, Sining Hu, Hongwei Du, Ning Li, Yongpeng Zou, Yanan Zou, Shenhong Jing, Yan Wang, Rong Sun, Bo Yu   +11 more
doaj   +1 more source

NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy

Frontiers in Pharmacology, 2022
Diabetic cardiomyopathy (DCM) is a prevalent complication in patients with diabetes, resulting in high morbidity and mortality. However, the molecular mechanisms of diabetic cardiomyopathy have yet to be fully elucidated. In this study, we investigated a
Dandan Zhang, Dandan Zhang, Yilan Li, Yilan Li, Weijie Wang, Weijie Wang, Xueyan Lang, Xueyan Lang, Yanxiu Zhang, Yanxiu Zhang, Qianqian Zhao, Qianqian Zhao, Jingru Yan, Jingru Yan, Yao Zhang, Yao Zhang   +15 more
doaj   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source

Effect of Puerarin on Expression of Fas/FasL mRNA in Pulmonary Injury induced by Ischemia-Reperfusion in Rabbits

Natural Product Communications, 2015
The effect of puerarin (Pur) on expressions of Fas/FasL mRNAs in pulmonary ischemia and reperfusion injury (PIRI) in rabbit was investigated. The sole side lung ischemia and reperfusion model was used.
Mengxiao Zheng, Dong Song, Ziyin Luo, Zhongqiu Lu, Yiming Wu, Wantie Wang   +5 more
doaj   +1 more source