Results 11 to 20 of about 999,788 (310)
Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury [PDF]
Frontiers in Aging Neuroscience, 2021 Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In recent years, reperfusion treatments based on thrombolytic and thrombectomy are major managements for ischemic stroke patients, and the recanalization time window has been extended to over 24 h.
Luoan Shen +8 more
openaire +4 more sources
International Journal of Molecular Sciences, 2021 Its increasing incidence has led stroke to be the second leading cause of death worldwide. Despite significant advances in recanalization strategies, patients are still at risk for ischemia/reperfusion injuries in this pathophysiology, in which ...
Anamaria Jurcău, A. Simion
semanticscholar +1 more source
Signal Transduction and Targeted Therapy, 2022 Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease characterized by injury to cardiomyocytes leading to various forms of cell death.
Xiao-hui Ma +10 more
semanticscholar +1 more source
Phytomedicine, 2022 BACKGROUND Mitophagy plays a critical role in cerebral ischemia/reperfusion by timely removal of dysfunctional mitochondria. In mammals, PINK1/Parkin is the most classic pathway mediating mitophagy.
Zhiguo Mao +7 more
semanticscholar +1 more source
Bioactive Materials, 2021 Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial infarction, but morbidity and mortality of acute myocardial infarction are still high.
Tianjiao Zhao +6 more
semanticscholar +1 more source
Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury
Frontiers in Molecular Neuroscience, 2020 The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu +6 more
semanticscholar +1 more source
Global vascular guidelines on the management of chronic limb-threatening ischemia
Journal of Vascular Surgery, 2019 Chronic limb-threatening ischemia (CLTI) is associated with mortality, amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are focused on definition, evaluation, and management of CLTI with the goals of improving evidence ...
M. Conte +58 more
semanticscholar +1 more source
Recommended standards for reports dealing with lower extremity ischemia: revised version.
Journal of Vascular Surgery, 1997 Recommended standards for analyzing and reporting on lower extremity ischemia were first published by the Journal of Vascular Surgery in 1986 after approval by the Joint Council of The Society for Vascular Surgery and the North American Chapter of the ...
R. Rutherford +6 more
semanticscholar +1 more source
Current Mechanistic Concepts in Ischemia and Reperfusion Injury
Cellular Physiology and Biochemistry, 2018 Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu +7 more
semanticscholar +1 more source
Cell Death and Differentiation, 2019 Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various diseases such as cancer, Parkinson’s disease, and stroke.
Yang Li +10 more
semanticscholar +1 more source