Results 11 to 20 of about 543,435 (265)

Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome

Frontiers in Cardiovascular Medicine, 2021
Plaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging.
Xing Luo, Xing Luo, Ying Lv, Ying Lv, Xiaoxuan Bai, Xiaoxuan Bai, Jinyu Qi, Jinyu Qi, Xiuzhu Weng, Xiuzhu Weng, Shaoyu Liu, Shaoyu Liu, Xiaoyi Bao, Xiaoyi Bao, Haibo Jia, Haibo Jia, Bo Yu, Bo Yu   +17 more
doaj   +1 more source

Achieved low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio predicts the pathophysiological evolution of lipid-rich plaques in acute coronary syndromes: an optical coherence tomography study

Frontiers in Cardiovascular Medicine, 2023
BackgroundAs a novel lipoprotein ratio, baseline low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (LHR) is closely related to the clinical outcomes of acute coronary syndromes (ACS) after percutaneous coronary ...
Luping He, Luping He, Boling Yi, Boling Yi, Dirui Zhang, Dirui Zhang, Sining Hu, Sining Hu, Chen Zhao, Chen Zhao, Rui Sun, Rui Sun, Jianlin Ma, Jianlin Ma, Jingbo Hou, Jingbo Hou, Haibo Jia, Haibo Jia, Lijia Ma, Lijia Ma, Bo Yu, Bo Yu   +21 more
doaj   +1 more source

C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

Frontiers in Pharmacology, 2021
Hyperglycemia-induced endothelial cell senescence has been widely reported to be involved in the pathogenesis of type 2 diabetes mellitus‒accelerated atherosclerosis.
Gang Wang, Gang Wang, Baihe Han, Baihe Han, Ruoxi Zhang, Qi Liu, Qi Liu, Xuedong Wang, Xuedong Wang, Xingtao Huang, Xingtao Huang, Dandan Liu, Dandan Liu, Weishen Qiao, Weishen Qiao, Mengyue Yang, Mengyue Yang, Xing Luo, Xing Luo, Jingbo Hou, Jingbo Hou, Bo Yu, Bo Yu   +22 more
doaj   +1 more source

Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia

Journal of Neuroinflammation, 2020
Background Recent findings describe microglia as modulators of neurogenesis in the subventricular zone (SVZ). SVZ microglia in the adult rat are thought to adopt a neurotrophic phenotype after ischemic stroke.
Urs Fisch, Catherine Brégère, Florian Geier, Laurie Chicha, Raphael Guzman   +4 more
doaj   +1 more source

Relationship between non-culprit lesion plaque characteristics changes and in-stent neoatherosclerosis formation: 1-year follow-up optical coherence tomography study

Reviews in Cardiovascular Medicine, 2021
The relationship between the in-stent neoatherosclerosis (ISNA) formation and the plaque’s characteristic changes in the non-culprit lesion is unclear.
Lei Xing, Yongpeng Zou, Chao Fu, Xiaoying Fan, Xuedong Wang, Qi Liu, Mengyue Yang, Dandan Liu, Linxing Feng, Jingbo Hou, Xingtao Huang   +10 more
doaj   +1 more source

Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury [PDF]

Frontiers in Aging Neuroscience, 2021
Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In recent years, reperfusion treatments based on thrombolytic and thrombectomy are major managements for ischemic stroke patients, and the recanalization time window has been extended to over 24 h.
Luoan Shen, Qinyi Gan, Youcheng Yang, Cesar Reis, Zheng Zhang, Shanshan Xu, Tongyu Zhang, Chengmei Sun, Chengmei Sun   +8 more
openaire   +3 more sources

Effect of Puerarin on Expression of Fas/FasL mRNA in Pulmonary Injury induced by Ischemia-Reperfusion in Rabbits

Natural Product Communications, 2015
The effect of puerarin (Pur) on expressions of Fas/FasL mRNAs in pulmonary ischemia and reperfusion injury (PIRI) in rabbit was investigated. The sole side lung ischemia and reperfusion model was used.
Mengxiao Zheng, Dong Song, Ziyin Luo, Zhongqiu Lu, Yiming Wu, Wantie Wang   +5 more
doaj   +1 more source

Non-culprit plaque characteristics in acute coronary syndrome patients with raised hemoglobinA1c: an intravascular optical coherence tomography study

Cardiovascular Diabetology, 2018
Background Raised hemoglobinA1c (HbA1c) is an indicator of pre-diabetes, which is associated with increased risk of coronary artery disease. However, the detailed morphological characteristics of non-culprit plaques in acute coronary syndrome (ACS ...
Shaotao Zhang, Jiannan Dai, Haibo Jia, Sining Hu, Hongwei Du, Ning Li, Yongpeng Zou, Yanan Zou, Shenhong Jing, Yan Wang, Rong Sun, Bo Yu   +11 more
doaj   +1 more source

Persistent Cigarette Smoking Attenuates Plaque Stabilization in Response to Lipid-Lowering Therapy: A Serial Optical Coherence Tomography Study

Frontiers in Cardiovascular Medicine, 2021
Objective: This study aimed to investigate the effect of smoking on morphological changes in non-culprit plaques in acute coronary syndrome (ACS) patients at 1 year after percutaneous coronary intervention (PCI), using optical coherence tomography (OCT ...
Xiling Zhang, Xiling Zhang, Xiang Peng, Xiang Peng, Lulu Li, Lulu Li, Huai Yu, Huai Yu, Bo Yu, Bo Yu   +9 more
doaj   +1 more source

Autophagy in myocardial ischemia and ischemia/reperfusion

Cardiovascular Pathology
Myocardial infarction (MI) is a life-threatening condition that leads to loss of viable heart tissue. The best way to treat acute MI and limit the infarct size is to re-open the occluded coronary artery and restore the supply of oxygenated and nutrient-rich blood, but reperfusion can cause additional damage.
Aleksandra Aljakna Khan, Sara Sabatasso
openaire   +2 more sources