Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen +5 more
doaj +1 more source
Ferroptosis: A Potential Target in Cardiovascular Disease
Ferroptosis is a new form of regulatory cell death characterized by iron-dependent and intracellular lipid peroxidation. Ferroptosis can be divided into two stages.
Yanlong Leng +9 more
doaj +1 more source
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Schauer, R. +11 more
core +1 more source
Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome
Plaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging.
Xing Luo +17 more
doaj +1 more source
The spectrum of Ischemia-induced white matter injury varies with age [PDF]
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Zammit, Christian +2 more
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Application of a novel method for subsequent evaluation of sinusoids and postsinusoidal venules after ischemia-reperfusion injury of rat liver [PDF]
Although several intravital fluorescence microscopic studies demonstrated that microcirculatory derangement is induced during liver ischemia-reperfusion, these data were obtained from randomly selected microvascular areas and microvessels, Repeated ...
Todoroki, T. +5 more
core +1 more source
Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro
Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin +6 more
doaj +1 more source
Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Kiprianova, Irina +6 more
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Monitoring of lung edema by microwave reflectometry during lung ischemia-reperfusion injury in vivo [PDF]
It is still unclear whether lung edema can be monitored by microwave reflectometry and whether the measured changes in lung dry matter content (DMC) are accompanied by changes in PaO(2) and in pro-to anti-inflammatory cytokine expression (IFN-gamma and ...
Metzger, R. P. +6 more
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Protecting the ischemic heart : pharmacological protection against myocardial ischemia in rats in vivo and in vitro [PDF]
Today in Switzerland approximately 40% of all deaths are due to cardiovascular diseases. More than half of these are due to ischemic heart disease. Among the fatal consequences of ischemic heart disease are life-threatening arrhythmias and myocardial ...
Butz, Silvia
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