Results 31 to 40 of about 544,745 (346)

Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]

, 2007
Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Buchan, Keith G., Croal, Bernard L., Cuthbertson, Brian, El-Shafei, Hussein, Gibson, George, Gibson, Patrick H., Hillis, Graham S., Ifezulike, Ada I., Jeffrey, Robert R., Small, Gary R.   +9 more
core   +1 more source

Effects of cardiopulmonary bypass on propofol pharmacokinetics and bispectral index during coronary surgery [PDF]

, 2009
PURPOSE: Cardiopulmonary bypass is known to alter propofol pharmacokinetics in patients undergoing cardiac surgery. However, few studies have evaluated the impact of these alterations on postoperative pharmacodynamics. This study was designed to test the
BARBOSA, Ricardo Antonio G., CARMONA, Maria José C., MALBOUISSON, Luiz M. S., PEREIRA, Valéria A., SANTOS, Silvia Regina C. Jorge, SILVA FILHO, Carlos R., WHITE, Paul F.   +6 more
core   +5 more sources

A comparison of sequential total and activated white cell count in patients undergoing coronary artery bypass grafting, using cardiopulmonary bypass, with and without a white cell filter

, 1999
Introduction Cardiopulmonary bypass (CPB) has been shown to induce a systemic inflammatory response similar to the local reaction seen after tissue damage [1].
D Johnson, DC Smith, JK Kirklin, JK Nanson, M Kulkarni, PJ Thurlow, SV Sheppard   +6 more
core   +1 more source

Visualisation of tissue kallikrein, kininogen and kinin receptors in human skin following trauma and in dermal diseases [PDF]

, 2004
During dermal injury and inflammation the serine proteases kallikreins cleave endogenous, multifunctional substrates (kininogens) to form bradykinin and kallidin.
Bhoola, Kanti D., Naidoo, Strinivasen, Neuhof, Christiane, Neuhof, Heinz, Sander, Christian, Schremmer-Danninger, Elisabeth, Snyman, Celia, Valeske, Klaus   +7 more
core   +1 more source

The effect of perioperative dexmedetomidine on postoperative delirium in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis of randomized controlled trials

BMC Anesthesiology
Background Dexmedetomidine is considered to have neuroprotective effects and may reduce postoperative delirium in both cardiac and major non-cardiac surgeries.
Xiaoli Zhuang, Lin Fu, Lan Luo, Ziyuan Dong, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei   +7 more
doaj   +1 more source

Evolution of Cardiopulmonary Bypass [PDF]

Circulation, 2009
At the end of the Second World War, the devastation of many cities in Europe, combined with the problems of reconstruction and loss of financial support, had brought European medical research to a halt. On the other hand, in the United States the war brought about an enormous amount of scientific research through the development of nuclear weapons, the
openaire   +2 more sources

Improvement of Hemocompatibility in Passive Cardiovascular Implant Devices

Advanced Therapeutics, EarlyView.
With the ever‐increasing reliance on cardiovascular devices and implants, minimizing their impact on blood is vital for their continued success. This review investigates the common methods of tackling this challenge through careful selections of material and surface modifications.
Shiyen L. Perera, Christoph E. Hagemeyer, Julian A. Smith, Josie Carberry, Be'eri Niego   +4 more
wiley   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Effects of different doses of ulinastatin on organ protection of deep hypothermic circulatory arrest in rats

Journal of Cardiothoracic Surgery
Background Deep hypothermic circulatory arrest (DHCA) can cause systemic inflammatory response (SIR) and ischemia-reperfusion (I/R) injury, potentially exacerbating organ failure. Ulinastatin (UTI) is a frequently employed anti-inflammatory medication in
Yuan Teng, Jing Wang, Zhiyuan Bo, Tianlong Wang, Yuan Yuan, Guodong Gao, Bingyang Ji, Qiang Hu   +7 more
doaj   +1 more source

Innovations in Pedriatic Cradiopulmonary Bypass: a continuous process of quality improvement [PDF]

, 2011
Cardiopulmonary bypass (CPB) is defined as a technique that temporarily replaces the function of the heart and lungs, maintaining an adequate blood circulation and oxygen content of the body during surgery of the heart and great vessels.
Golab, H.D. (Hanna)
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