Results 31 to 40 of about 78,358 (263)

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Pioneer of Cardiothoracic Surgery - Joaquim Cavalcanti

Brazilian Journal of Cardiovascular Surgery, 2023
Joaquim de Souza Cavalcanti was a pioneer among us - the Brazilian State of Pernambuco and North-Northeast region - in cardiac surgery in its initial phase (Blalock-Taussig surgery and mitral valvulotomy), in thoracic surgery (pneumectomy, lung lobectomy
Ricardo de Carvalho Lima, Fernando de Souza Cavalcanti, Leonardo Pontual Lima   +2 more
doaj   +1 more source

STING Agonist‐Modified Tumor Targeting Photosensitizer Remodels Cancer‐Associated Fibroblasts to Potentiate Photoimmunotherapy in Pancreatic Cancer

Advanced Science, EarlyView.
This carrier‐free, esterase‐responsive nanoaggregate integrates a mitochondria‐targeting photosensitizer with a non‐nucleotide STING agonist to achieve localized photoactivation and immune reprogramming. ICyM2 remodels tumor stroma, induces potent immunogenic cell death, and triggers intratumoral STING activation, collectively revitalizing the ...
Yixuan Zhang, Shankun Yao, Yihan Zhao, Saisai Zhu, Wen Fang, Ranran Yu, Naiwen Shi, Ruixin Zhang, Yin Zhang, Jiawei Liang, Ziying Zhang, Shijin Xu, Ziwei Zhang, Jiajun Zhang, Yukun Li, Xiaoxuan Han, Yuncong Chen, Shu Zhang, Ying Lv   +18 more
wiley   +1 more source

Continuous electrocardiogram monitoring in porcine model of myocardial ischemia reperfusion

Animal Models and Experimental Medicine, EarlyView.
Wearable technology for continuous electrocardiogram monitoring can be utilized in porcine models of disease. Abstract As cardiovascular disease is the leading cause of global mortality, innovative animal models are vital to demonstrating the translational value of experimental discoveries. Investigations focused on myocardial remodeling after ischemia
Nathaniel Hyams, Roxanne Swagel, Sharon Thomas, Rupak Mukherjee, Alicia Braxton Hickman, Daniel Eldridge, Kristine Helke, Ying Mei, Jean Marie Ruddy   +8 more
wiley   +1 more source

Reduced costs for Staphylococcus aureus carriers treated prophylactically with mupirocin and chlorhexidine in cardiothoracic and orthopaedic surgery. [PDF]

PLoS ONE, 2012
BACKGROUND: A multi centre double-blind randomised-controlled trial (M-RCT), carried out in the Netherlands in 2005-2007, showed that hospitalised patients with S.
Miranda M L van Rijen, Lonneke G M Bode, Diane A Baak, Jan A J W Kluytmans, Margreet C Vos   +4 more
doaj   +1 more source

Prospective, Multicenter Evaluation of Transcarotid Artery Revascularization in Standard‐Risk Patients: 30‐Day Outcomes of the ROADSTER 3 Study

Annals of Neurology, EarlyView.
Objective To evaluate the real‐world safety and efficacy for standard surgical risk patients with extracranial internal carotid artery disease undergoing transcarotid artery revascularization. Methods ROADSTER 3 is a prospective, multicenter, single‐arm post‐approval study.
Jeffrey Jim, Meghan Dermody, Brian Peterson, Scott S. Berman, Nicolas J. Mouawad, Joseph Ricotta, Naveed Saqib, Peter Faries, Angela Martin, Joshua D. Adams, Uttam Tripathy, Daniel Calderon, David O'Connor, Rasesh Shah, Sumaira Macdonald, Marc L. Schermerhorn   +15 more
wiley   +1 more source

Medical students’ perceptions of mentorship in cardiothoracic surgery: A Thoracic Surgery Medical Student Association Nationwide SurveyCentral MessagePerspective

JTCVS Open
Objective: The study objective was to explore medical students' perceptions of mentorship in cardiothoracic surgery in the United States. Methods: A voluntary, anonymous electronic survey was distributed to medical students through the Thoracic Surgery ...
Carlos E. Diaz-Castrillon, MD, Cynthia Rangel, MS, John A. Treffalls, BS, Kristian Punu, BS, Naima Alver, MD, Lena Trager, MD, Ravi K. Ghanta, MD, Victor O. Morell, MD, Ibrahim Sultan, MD   +8 more
doaj   +1 more source

Asymptomatic mediastinal extra-adrenal paraganglioma as a cause of sudden death: a case Report

Open Life Sciences, 2019
A 23-year-old female patient was referred for treatment of a posterior mediastinal tumour. There was no history of hypertension or headache and no other complaints.
Xu Qiancheng, Cao Yingya, Yin Hongzhen, Wu Rongrong, Yu Tao, Lu Weihua   +5 more
doaj   +1 more source

Effectiveness of Liposomal Bupivacaine Compared With Standard-of-Care Measures in Pediatric Cardiothoracic Surgery: A Retrospective Cohort Study [PDF]

, 2021
Christopher F. Tirotta, Jennifer Lin, Mary Helen Tran   +2 more
openalex   +1 more source

Extremity Function After Transfemoral Transcatheter Aortic Valve Implantation: A TAVI XS Sub‐Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Physical decline after transcatheter aortic valve implantation (TAVI) is associated with worse outcomes. However, data on post‐TAVI extremity function are limited. This sub‐study of the TAVI XS trial aimed to assess extremity function after transfemoral TAVI, evaluate functional decline, compare outcomes between upper‐and lower ...
Geert A. A. Versteeg, Maxim J. P. Rooijakkers, Kimberley I. Hemelrijk, Pieter J. Vlaar, Daniël C. Overduin, Marleen H. van Wely, Hugo M. Aarts, Dirk‐Jan van Ginkel, Niels A. Stens, Lokien X. van Nunen, Robert Jan van Geuns, Leen A. F. M. van Garsse, Guillaume S. C. Geuzebroek, Michel W. A. Verkroost, Aysun Cetinyurek‐Yavuz, Robin H. Heijmen, Dick H. J. Thijssen, Jurrien M. ten Berg, Pim A. L. Tonino, Ronak Delewi, Niels van Royen   +20 more
wiley   +1 more source