Results 31 to 40 of about 96,818 (297)
Rationale and design of the randomized ‘early ventricular assist device’—Trial (VAD‐DZHK3)
ESC Heart Failure, EarlyView.The VAD‐DZHK3 trial is a randomised controlled study evaluating whether elective LVAD implantation improves outcomes in end‐stage heart failure (HF) patients listed for heart transplantation compared with delayed implantation after clinical deterioration.Christoph Knosalla, Gloria Färber, Andreas J. Rieth, Rolf Wachter, Marius Placzek, Wolfgang Albert, Gerd Hasenfuß, Volkmar Falk, Tim Friede, for the VAD‐DZHK3 Investigators +9 morewiley +1 more sourceMinimization or withdrawal of oral pharmacotherapy in chronic heart failure patients with improved myocardial function: A systematic review
European Journal of Heart Failure, EarlyView.This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy.Yuxiang Luo, Wenbin Xiao, Yusuf Z. Sener, Wouter C. Meijers, Robert M.A. van der Boon, Elfatih A. Hasabo, Osama Soliman, Rudolf A. de Boer, Kadir Caliskan +8 morewiley +1 more sourceLung ultrasound and mortality in a cardiogenic shock population: A prospective registry‐based analysis
European Journal of Heart Failure, EarlyView.Lung ultrasound (LUS) and mortality in cardiogenic shock (CS) patients. Abstract Aims
Lung ultrasound (LUS) is a widely used technique to assess de‐aeration in critically ill patients with respiratory failure. There is paucity of data on LUS in cardiogenic shock (CS).Guido Tavazzi, Costanza Natalia Julia Colombo, Matteo Pagnesi, Maurizio Bertaina, Andrea Montisci, Simone Frea, Marco Marini, Martina Briani, Lisa Patrini, Francesca Rossi, Letizia Bertoldi, Giulia Maj, Giovanna Viola, Carlotta Sorini Dini, Serafina Valente, Gaetano Maria De Ferrari, Nuccia Morici, Federico Pappalardo, Alice Sacco, on behalf of the Altshock Group +19 morewiley +1 more sourceKidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study
European Journal of Heart Failure, EarlyView.Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.Jonas Sundermeyer, Caroline Kellner, Benedikt N. Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak‐Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Sven Möbius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, P. Christian Schulze, Robert H.G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B. Winzer, Dirk Westermann, Benedikt Schrage +41 morewiley +1 more sourceThe crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC
European Journal of Heart Failure, EarlyView.Abstract
A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...Gabriele Fragasso, Davide Stolfo, Markus S. Anker, Antoni Bayes‐Genis, Ovidiu Chioncel, Stephane Heymans, Pardeep S. Jhund, Basil S. Lewis, Gary D. Lopaschuk, Lars H. Lund, Arantxa Gonzalez, Matteo Pagnesi, Gabriele Giacomo Schiattarella, Carlo Gabriele Tocchetti, Peter van der Meer, Sophie Van Linthout, Sven Wassmann, B. Daan Westenbrink, Marco Metra, Giuseppe M.C. Rosano, Gianluigi Savarese +20 morewiley +1 more sourceComputational modelling of myocardial metabolism in patients with advanced heart failure
European Journal of Heart Failure, EarlyView.LV, left ventricular; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction. Abstract Aims
Perturbations of myocardial metabolism and energy depletion are well‐established hallmarks of heart failure (HF), yet methods for their systematic assessment remain limited in humans.Niklas Beyhoff, Vera M. Braun, Marieluise Kirchner, Lucy E.M. Finnigan, Christoph Knosalla, István Baczkó, Evgenij Potapov, Ulrich Kintscher, Tilman Grune, Titus Kuehne, Hermann‐Georg Holzhütter, Philipp Mertins, Damian J. Tyler, Hendrik Milting, Betty Raman, Oliver J. Rider, Stefan Neubauer, Nikolaus Berndt +17 morewiley +1 more sourceHeart failure hospitalizations and clinical outcomes in patients undergoing tricuspid transcatheter edge‐to‐edge repair: Insights from EuroTR
European Journal of Heart Failure, EarlyView.Heart failure hospitalization before and after tricuspid transcatheter edge‐to‐edge repair. CI, confidence interval; eGFR, estimated glomerular filtration rate; EuroTR Registry, European Registry of Transcatheter Repair for Tricuspid Regurgitation; GGT, gamma‐glutamyl transferase; Hb, haemoglobin; HFH, heart failure hospitalization; HR, hazard ratio ...Daniela Tomasoni, Marianna Adamo, Jörg Hausleiter, Elisa Pezzola, Karl‐Patrik Kresoja, Jennifer von Stein, Vera Fortmeier, Christoph Pauschinger, Wolfgang Rottbauer, Mohammad Kassar, Bjoern Goebel, Paolo Denti, Paul Achouh, Tienush Rassaf, Manuel Barreiro‐Perez, Peter Boekstegers, Andreas Rück, Monika Zdanyte, Flavien Vincent, Philipp Schlegel, Ralph‐Stephan von Bardeleben, Mirjam G. Wild, Christian Besler, Stephanie Brunner, Stefan Toggweiler, Julia Grapsa, Tiffany Patterson, Holger Thiele, Tobias Kister, Giuseppe Tarantini, Giulia Masiero, Marco De Carlo, Alessandro Sticchi, Mathias H. Konstandin, Eric Van Belle, Tobias Geisler, Rodrigo Estévez‐Loureiro, Peter Luedike, Nicole Karam, Francesco Maisano, Philipp Lauten, Fabien Praz, Mirjam Kessler, Daniel Kalbacher, Volker Rudolph, Christos Iliadis, Philipp Lurz, Lukas Stolz, Marco Metra, the EuroTR Investigators, Edoardo Pancaldi, Luca Branca, Ludwig T. Weckbach, Julia Novotny, Roman Pfister, Stephan Baldus, Muhammed Gerçek, Felix Rudolph, Sebastian Ludwig, Benedikt Koell, Leonhard‐Moritz Schneider, Dominik Felbel, Carsten Salomon, Harald Lapp, Tania Puscas, Alain Berrebi, Amir Abbas Mahabadi, Florian Schindhelm, Berenice Caneiro‐Queija, Julio C. Echarte, Jürgen Schreieck, Andreas Goldschmied, Natacha Rousse, Samy Aghezzaf, Norbert Frey, Martin J. Kraus, Leonie Ziegler, Sebastian Rosch, Federico Arturi, Andrea Panza, Matteo Mazzola, Cristina Giannini +81 morewiley +1 more sourceHigher hospital volume is associated with lower mortality for patients with cardiogenic shock and mechanical circulatory support
European Journal of Heart Failure, EarlyView.Is cardiogenic shock (CS) best treated locally with short transport times and multiple shock centres? Or is a central, standardized provision of care for CS and especially use of mechanical circulatory support (MCS) better for patients? Annualized volume of CS and MCS cases vary widely at the hospital level.Angela Dettling, Caroline Kellner, Jonas Sundermeyer, Benedikt N. Beer, Lisa Besch, Marvin Kriz, Stefan Kluge, Paulus Kirchhof, Stefan Blankenberg, Benedikt Schrage +9 morewiley +1 more sourcePharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis
Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract
Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...Xue Zheng, Jing Li, Zhao‐Qiong Zhuwiley +1 more source