Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo+27 more
wiley +1 more source
L-space surgeries on 2-component L-space links [PDF]
In this paper, we analyze L-space surgeries on two component L-space links. We show that if one surgery coefficient is negative for the L-space surgery, then the corresponding link component is an unknot. If the link admits very negative (i.e. $d_{1}, d_{2}\ll0$) L-space surgeries, it is the Hopf link. We also give a way to characterize the torus link $
arxiv +1 more source
Welcome to the 26th Annual Conference of the World Society of Cardiothoracic Surgery and the 17th Annual Congress of the South African Heart Association. [PDF]
On behalf of the organising committee we would like to welcome you to the 26th Annual Conference of the World Society of Cardiothoracic Surgery. The conference is jointly hosted by the Society of Cardiothoracic Surgeons of South Africa and the South ...
Kleinloog, Robert+1 more
core +2 more sources
Cardioprotective effects of semaglutide on isolated human ventricular myocardium
Semaglutide reduces late sodium current (INa) and diastolic calcium (Ca) sparks in human cardiomyocytes from aortic stenosis (AS) and end‐stage heart failure with reduced ejection fraction (HFrEF) patients, thereby increasing Ca transients. Improved Ca storage may underly the enhanced contractility of human cardiomyocytes upon semaglutide.
Thomas Krammer+16 more
wiley +1 more source
Abstract Objective Prior to 2019, termination of pregnancy (TOP) was unlawful in Ireland. We sought to examine the impact of legislative change on TOP for major congenital heart disease (CHD) and its effect on parental decision‐making regarding the options of complex surgery, TOP, or palliative perinatal care.
Fiona Cody+7 more
wiley +1 more source
Graduate programs in surgical education: celebrating the first decade
ANZ Journal of Surgery, Volume 92, Issue 12, Page 3141-3144, December 2022.
Debra Nestel+2 more
wiley +1 more source
Somatic growth in single ventricle patients: A systematic review and meta‐analysis
Abstract Aim To map somatic growth patterns throughout Fontan palliation and summarise evidence on its key modifiers. Methods Databases were searched for relevant articles published from January 2000 to December 2021. Height and weight z scores at each time point (birth, Glenn procedure, Fontan procedure and >5 years after Fontan completion) were ...
Jef Van den Eynde+8 more
wiley +1 more source
Ex-vivo recruitment and x-ray assessment of donor lungs in a challenging retrieval from a donor supported by lvad using the portable normothermic perfusion system: A case report [PDF]
Lung transplantation (LTx) is limited by the shortage of suitable donors. To overcome this problem, many programs have begun to use donors with extended criteria (marginal donors).
Calabrese, Fiorella+7 more
core +1 more source
Unsupervised Domain Adaptation for Automatic Estimation of Cardiothoracic Ratio [PDF]
The cardiothoracic ratio (CTR), a clinical metric of heart size in chest X-rays (CXRs), is a key indicator of cardiomegaly. Manual measurement of CTR is time-consuming and can be affected by human subjectivity, making it desirable to design computer-aided systems that assist clinicians in the diagnosis process.
arxiv
Preoperative and perioperative use of levosimendan in cardiac surgery: European expert opinion [PDF]
In cardiac surgery, postoperative low cardiac output has been shown to correlate with increased rates of organ failure and mortality. Catecholamines have been the standard therapy for many years, although they carry substantial risk for adverse cardiac ...
A., Eremenko+26 more
core +1 more source