Results 41 to 50 of about 2,628,190 (315)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Atherosclerotic Cardiovascular Disease [PDF]

, 2011
Cardiovascular diseases (CVD) are still one of the leading causes of death in the world. The book Atherosclerotic Cardiovascular Disease is a contribution to the application of new knowledge in the area of cardiovascular diseases.

core   +2 more sources

The Middle Ages Contributions to Cardiovascular Medicine

, 2016
The historical period called the Middle Ages, a long interval between the 5th and the 15th centuries, is still commonly known as the Dark Ages, especially in the area of health sciences.
Ranhel,André Silva, Mesquita,Evandro Tinoco, Ranhel, André Silva [UNESP], Ranhel, André Silva, Mesquita, Evandro Tinoco   +4 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Rates of Infections, Malignancies, Cardiovascular Outcomes, and Death in Individuals with Hospital-treated Alopecia Areata: A Registry-based Cohort Study in Denmark

Acta Dermato-Venereologica
The emergence of new systemic treatments for alopecia areata underscores the importance of estimating rates of potential treatment safety events among individuals with alopecia areata.
Sissel Brandt Toft Sørensen, Prethibha George, Oladayo Jagun, Robert Wolk, Lynne Napatalung, Samuel H. Zwillich, Lars Iversen, Vera Ehrenstein   +7 more
doaj   +1 more source

Coexisting morbidity burden in elderly hospitalized patients with and without heart failure

Hellenic Journal of Cardiology, 2022
Introduction: Aging, cardiovascular disease (CVD), and heart failure (HF) increase the coexisting morbidity (CM) burden. This study compared the contribution of HF with this increase in elderly patients hospitalized for CVD by comparing patients with and
Anthi Simou, Andrew Xanthopoulos, Grigorios Giamouzis, Dimitrios Papagiannis, Apostolos Dimos, Dimitrios Economou, John Skoularigis, Filippos Triposkiadis   +7 more
doaj   +1 more source

Comparative cost-effectiveness analyses of cardiovascular magnetic resonance and coronary angiography combined with fractional flow reserve for the diagnosis of coronary artery disease. [PDF]

, 2014
According to recent guidelines, patients with coronary artery disease (CAD) should undergo revascularization if significant myocardial ischemia is present.
Pilz, G., Steffen E Petersen, Pilz, G, Petersen, SE, Wasserfallen, J-B, Guenter Pilz, Petersen, S.E., Favre, David, Petersen, Steffen E., Anja Wagner, Schwitter, J.J., Pinget, C, Favre, D., Wagner, A, Wagner, A., Jean-Blaise Wasserfallen, Karine Moschetti, Moschetti, K., Moschetti, Karine, Wasserfallen, JB, Schwitter, J, Schwitter, Juerg, Wasserfallen, Jean-Blaise, David Favre, Schwitter, JJ, Christophe Pinget, Pinget, Christophe, Wasserfallen, J.B., Pilz, Guenter, Pinget, C., Wagner, Anja, Juerg J Schwitter, Moschetti, K, Favre, D   +33 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Pharmacological Management of Cardiovascular Risk Factors

, 2023
Cardiovascular disease is the number one cause of death across various continents, ethnicities, and economic classes. Therefore, its continued research and exploration into its pathomechanism is invaluable.
Jaber, Mohammed
core  

Alpha-Linolenic Acid: Is It Essential to Cardiovascular Health? [PDF]

, 2010
There is a large body of scientific evidence that has been confirmed in randomized controlled trials indicating a cardioprotective effect for omega-3 fatty acids from fish.
Brouwer, I.A., Johanna M. Geleijnse, Brouwer, I.A.; id_orcid, Geleijnse, J.M., Goede, J., de, Janette de Goede, Goede, J., Ingeborg A. Brouwer, de Goede, J.   +8 more
core   +1 more source