Results 201 to 210 of about 305,194 (262)

A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane, Christopher C. Striebich, Marie L. Feser, James R. O'Dell, Judith A. James, Jeffrey A. Sparks, John M. Davis III, Jonathan Graf, Maureen A. McMahon, Elizabeth B. Solow, Lindsy J. Forbess, Athan Tiliakos, Elena Schiopu, Maria I. Danila, Diane L. Horowitz, Jonathan Kay, Colin D. Strickland, Joel M. Guthridge, Cristina Arriens, Jennifer M. Grossman, M. Kristen Demoruelle, Elizabeth A. Bemis, Ashley Frazer‐Abel, Chelsie L. Fleischer, David A. Fox, Ted R. Mikuls, Melissa Greenleaf, Kate York, Sarah Walker, Lynette Keyes‐Elstein, Margie Byron, Janel Fedler, Ellen A. Goldmuntz, V. Michael Holers   +33 more
wiley   +1 more source

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

Arthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller, Steven E. Harte, Richard E. Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R. Till, David A. Williams, Chad M. Brummett, Neil Basu, Sawsan As‐Sanie, Daniel J. Clauw   +15 more
wiley   +1 more source

Efficacy and Safety of Guselkumab in Participants with Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of the Phase 3, Randomized, Placebo‐Controlled SOLSTICE Study

Arthritis &Rheumatology, Accepted Article.
Objective Evaluate the efficacy and safety of guselkumab, an interleukin‐23p19‐subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor inhibitor (TNFi‐IR).
Alexis Ogdie, Joseph F Merola, Philip J Mease, Christopher T Ritchlin, Jose U Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B Gottlieb   +12 more
wiley   +1 more source

Electrocardiogram abnormalities in patients with acne undergoing isotretinoin therapy: a focused review. [PDF]

An Bras Dermatol
Islam AW, Motdhare P, Mohan S, Bejoy S, Wilkhoo HS.   +4 more
europepmc   +1 more source

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Cardiovascular abnormalities in Klinefelter Syndrome

International Journal of Cardiology, 2013
Several epidemiological studies have demonstrated an increased mortality from cardiovascular causes in patients with Klinefelter Syndrome (KS). Little information is available about the nature of the underlying cardiovascular abnormalities. Aim of the study was to investigate exercise performance, left ventricular architecture and function, vascular ...
Daniela Pasquali, ARCOPINTO, MICHELE, Andrea Renzullo, Mario Rotondi, Giacomo Accardo, Andrea Salzano, Daniela Esposito, SALDAMARCO, LAVINIA, Andrea M. Isidori, MARRA, ALBERTO MARIA, RUVOLO, ANTONIO, NAPOLI, RAFFAELE, Andrea Lenzi, Ragavendra R. Baliga, SACCA', LUIGI, CITTADINI, ANTONIO, Eduardo Bossone   +16 more
openaire   +4 more sources

Cardiovascular abnormalities in thoracopagus twins

Teratology, 1981
AbstractA detailed anatomopathologic study of the various developmental malformations encountered in a set of female thoracopagus twins is presented. Special emphasis has been devoted to the analysis and description of the complex cardiovascular abnormalities associated with the conjoined heart and liver of this set of twins.
M, Marin-Padilla, A J, Chin, T M, Marin-Padilla   +2 more
openaire   +2 more sources

Cardiovascular Abnormalities in Myotonic Dystrophy

Chest, 1973
A 44-year-old patient with myotonic dystrophy and cardiac involvement is presented with the unusual feature of persistent atrial flutter for over 34 months. Focal myocardial dysfunction demonstrated by left ventriculography simulated similar findings in ischemic heart disease. Coronary angiography revealed, however, normal coronary arterial tree.
J, Salomon, R M, Easley
openaire   +2 more sources