Results 151 to 160 of about 4,824,048 (369)
Advanced Oral Delivery Systems for Nutraceuticals
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang+4 more
wiley +1 more source
Cardiovascular complications of conventional and targeted adjuvant breast cancer therapy [PDF]
Adjuvant therapy has improved the survival of women with early breast cancer (BC). Meta-analyses suggest that anthracycline-based regimens reduced the annual BC death rate by ∼40% in women below the age of 50 and 20% in older women. Novel agents designed
De Laurentiis, M.+4 more
core
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren+13 more
wiley +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee+9 more
wiley +1 more source
Direct healthcare costs of diabetes mellitus patients in Spain [PDF]
Objectives. To estimate the healthcare resources spent by diabetic patients in Spain during the year 2002. Methods. The present work is a cost-of-illness study.
Lobo, Félix+3 more
core +3 more sources
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Blood pool MR contrast agents for cardiovascular imaging [PDF]
Maythem Saeed+2 more
openalex +2 more sources
Cardiovascular effects of iodinated contrast agents
The ideal intravascular contrast agent would be biologically inert and have no pharmacologic actions. Pharmacologic actions of currently used radiographic contrast agents are determined principally by 3 physicochemical properties of the iodine-bearing molecule and its formulation: osmolality, sodium concentration and calcium-binding properties.
openaire +3 more sources
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim+11 more
wiley +1 more source
Cardiovascular effects of the novel arteriovenous dilator agent, flosequinan in conscious dogs and cats [PDF]
M.F. Sim+3 more
openalex +1 more source