Results 21 to 30 of about 5,834 (244)

New antiplatelet agents for cardiovascular disease [PDF]

open access: yesCanadian Medical Association Journal, 2013
Antiplatelet therapy is a key component in the management of many medical diseases to decrease the risk of cardiovascular events.[1][1] Acetylsalicyclic acid (ASA) is the most common antiplatelet agent used and is usually first-line therapy. Use of clopidogrel, especially in combination with ASA,
Cesilia Nishi, Doson Chua
openaire   +3 more sources

More hemodynamic changes in hypertensive versus non-hypertensive patients undergoing breast cancer surgery in general anesthesia - a prospective clinical study [PDF]

open access: yesMedicinski Glasnik, 2009
Aim Preoperative comorbidity may significantly influence theconduction of anesthesia and patients’ outcome. The aim of thisstudy was to compare a number of anesthetic interventions and theuse of non-anesthetic drugs in hypertensive and non ...
Darija Azenić-Venžera   +9 more
doaj  

Frequency domain analysis of photoplethysmographic and arterial pressure waveforms for assessing hemodynamics in children with congenital heart surgery [PDF]

open access: yesKorean Journal of Anesthesiology
Background Time-domain parameters are less reliable in children due to increased arterial and chest wall compliance. We assessed the ability of indices derived from frequency analysis of photoplethysmography (PPG) and arterial blood pressure (ABP ...
Hwa-Young Jang   +3 more
doaj   +1 more source

Uncontrolled and apparent treatment resistant hypertension: a cross-sectional study of Russian and Norwegian 40–69 year olds

open access: yesBMC Cardiovascular Disorders, 2020
Background Uncontrolled hypertension is a major cardiovascular risk factor. We examined uncontrolled hypertension and differences in treatment regimens between a high-risk country, Russia, and low-risk Norway to gain better understanding of the ...
Jakob Petersen   +10 more
doaj   +1 more source

Treatment of diabetes mellitus has borne much fruit in the prevention of cardiovascular disease

open access: yesJournal of Diabetes Investigation, 2022
Cardiovascular (CV) disease is the most alarming complication of diabetes mellitus (DM), and a strategy aiming at cardiovascular event prevention in diabetes mellitus has long been debated.
Hiroaki Yagyu, Hitoshi Shimano
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

The CANVAS Program: implications of canagliflozin on reducing cardiovascular risk in patients with type 2 diabetes mellitus

open access: yesCardiovascular Diabetology, 2019
Canagliflozin is a sodium glucose co-transporter 2 (SGLT2) inhibitor that reduces blood glucose, as well as blood pressure, body weight, and albuminuria in patients with type 2 diabetes mellitus (T2DM).
Salvatore Carbone, Dave L. Dixon
doaj   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Novel Antithrombotic Agents in Ischemic Cardiovascular Disease: Progress in the Search for the Optimal Treatment

open access: yesJournal of Cardiovascular Development and Disease, 2022
Ischemic cardiovascular diseases have a high incidence and high mortality worldwide. Therapeutic advances in the last decades have reduced cardiovascular mortality, with antithrombotic therapy being the cornerstone of medical treatment.
Ignacio Barriuso   +2 more
doaj   +1 more source

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