Results 311 to 320 of about 4,836,823 (371)

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

Advanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou, Keyun Li, Xiezong Hu, Shuhao Fan, Yuxuan Gao, Xiaoshu Xue, Yu Bu, Haoyi Zhang, Yili Wang, Chunjiao Wei, Shangrong Zhang, Zhongwen Xie, Chao Liu, Peng Chen, Zongjun Yin, Dalong Ren   +15 more
wiley   +1 more source

The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients. [PDF]

J Clin Hypertens (Greenwich)
Zhang S, Ma M, Li P, Yao S, Wang C, Wang X, He K, Xue H.   +7 more
europepmc   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

Prevalence of cardiovascular risk factors and disease in patients with schizophrenia: baseline results from a prospective cohort study with long-term clinical follow-up. [PDF]

Schizophrenia (Heidelb)
Polcwiartek C, Jensen SE, Frøkjær JB, Nielsen RE.   +3 more
europepmc   +1 more source

Cardiovascular medication use and health-related Quality of Life in older women with diabetes [PDF]

, 2009
Hikmayani, Nur Hafidha
core   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Thrombotic and cardiovascular events in HIV infection (Review). [PDF]

Biomed Rep
Dryllis G, Vasilopoulou M, Politou M, Gerogkiokas A, Pittaras T, Zoumpourlis V, Spandidos DA, Gialeraki A.   +7 more
europepmc   +1 more source

Assessing the Burden of Thromboembolic Complications in Outpatient COVID-19 Cases: A Focused Study on Patients Followed in Primary Care. [PDF]

Can J Infect Dis Med Microbiol
Usanma Koban B, Çelik Ö, Sur Ünal Ü, Uzuner A.   +3 more
europepmc   +1 more source

Potential New Applications of Sodium-Glucose Cotransporter-2 Inhibitors Across the Continuum of Cancer-Related Cardiovascular Toxicity. [PDF]

Pharmaceuticals (Basel)
Zebrowska AM, Borowiec A.
europepmc   +1 more source

Gliflozins in hypertension: basic mechanisms and clinical insights. [PDF]

Am J Physiol Renal Physiol
Rieg T, Liu R, Staruschenko A.
europepmc   +1 more source