Results 101 to 110 of about 797,541 (308)

Risk of Mortality (including Sudden Cardiac Death) and Major Cardiovascular Events in Users of Olanzapine and Other Antipsychotics: A Study with the General Practice Research Database. [PDF]

, 2013
Objective. Assess risk of cardiac events and mortality among users of olanzapine and other antipsychotics relative to nonusers. Methods. The General Practice Research Database was used to identify cohorts of antipsychotic users and nonusers with ...
Van Staa, Tjeerd; id_orcid, Murray-Thomas, Tarita, Motsko, Stephen, Brunner, Elizabeth, Jones, Meghan E, Campbell, Giedra, Patel, Deven, van Staa, Tjeerd P, Shatapathy, Chetan C   +8 more
core   +1 more source

Mitral Transcatheter Edge-to-Edge Repair and Clinical Value of Novel Echocardiographic Biomarkers: A Hypothesis-Generating Study

Biomedicines
Background: Longitudinal data on reverse cardiac remodeling and outcomes after transcatheter edge-to-edge repair (TEER) are limited. Methods: A total of 78 patients with severe mitral regurgitation (MR) were included retrospectively.
Javier Solsona-Caravaca, Rubén Fernández-Galera, Víctor González-Fernández, Lorenzo Airale, Johny Rivas, Luca Scudeler, Núria Vallejo, Gisela Teixidó-Turà, Guillem Casas, Filipa Valente, Ruper Oliveró, Yassin Belahnech, Gerard Martí, Bruno García, Ignacio Ferreira-González, José F. Rodríguez-Palomares, Laura Galian-Gay   +16 more
doaj   +1 more source

Cigarette smoking: an important renal risk factor – far beyond carcinogenesis

Tobacco Induced Diseases, 2003
In recent years, it has become apparent that smoking has a negative impact on renal function, being one of the most important remediable renal risk factors.
SR Orth
doaj   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study [PDF]

, 2012
<p>Background: Randomized controlled trials have shown the importance of tight glucose control in type 1 diabetes (T1DM), but few recent studies have evaluated the risk of cardiovascular disease (CVD) and all-cause mortality among adults with T1DM.
Looker, Helen C., Morris, Andrew D, Morris, Andrew D., Philip, Sam, Lindsay, Robert S., Pearson Donald W. M., Peden Norman R., Peden, Norman R., Chalmers John, Sullivan Frank, Pearson, D.W.M., Livingstone, S.J., Chalmers, John, Hothersall, Eleanor J, Sullivan, Frank, Eleanor J Hothersall, Pearson, Donald W M, Frank Sullivan (130218), Andrew D Morris, Donald W M Pearson, Norman R Peden, McKnight, J., Petrie, John R, Cleland, S., Sattar, N., Colhoun, Helen, Hothersall Eleanor J., Lindsay, Robert S, Wild, Sarah H.; id_orcid, Cleland, Stephen J., Colhoun Helen M., Morris, A.D., Lindsay, R.S., Sattar Naveed, Robert S Lindsay, Shona J. Livingstone (130173), Sam Philip (130216), Naveed Sattar (8785), McKnight, John, Helen C Looker, Leese, Graham P., Hothersall, Ellie, Graham P. Leese (130194), Norman R. Peden (130212), Sattar, Naveed, Sarah H. Wild (130180), Livingstone, Shona J, Graham P Leese, Petrie, John R., Colhoun, Helen M., Livingstone Shona J., Lindsay Robert S., Sarah H Wild, John Chalmers (130187), Pearson, Donald W., Looker, H.C., Pearson, Donald W. M., Cleland Stephen, Colhoun, H.M., Petrie, J.R., Colhoun, Helen M, Eleanor J. Hothersall (130177), John R Petrie, John Chalmers, Looker Helen C., Leese, Graham, Stephen Cleland (130190), Chalmers, J., Hothersall, E.J., Wild, Sarah H, Sullivan, F., Petrie, John, Livingstone, Shona J., Cleland, Stephen, Stephen Cleland, Peden, Norman R, Looker, Helen C, Helen M Colhoun, Morris Andrew D., Robert S. Lindsay (130182), Naveed Sattar, Livingstone, Shona, Leese Graham P., Andrew D. Morris (130204), Shona J Livingstone, Petrie John R., Helen C. Looker (130174), Leese, G.P., Wild, Sarah H., Wild, S.H., John R. Petrie (130214), John McKnight, Hothersall, Eleanor J., Morris, Andrew, Looker, Helen, Wild Sarah H., Philip Sam, McKnight, John A., Peden, N.R., Helen M. Colhoun (130220), Pearson, Donald W.M., Sam Philip, Leese, Graham P, Peden, Norman, Frank Sullivan, Philip, S., Donald W. M. Pearson (130208), John McKnight (130200), McKnight John   +108 more
core   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Background/Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs Rheumatoid Arthritis (VARA) Registry.
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

Artery‐on‐Chip Demonstrates Mechanical and Functional Features of Healthy and Diseased Living Smooth Muscle Tissue

Advanced Functional Materials, EarlyView.
This article details the development of an artery‐on‐chip platform for in vitro arterial disease modeling and therapeutic discovery. It describes the fabrication of a fibrin biomaterial scaffold seeded with iPSC‐derived smooth muscle and endothelial cells, mimicking native artery properties. Two genetic disease models showcase the platform's ability to
Danielle Yarbrough, Roy Chen, Katerina Katsouleas, Jaron Shoemaker, Travis Brady, Tianfang Yu, Jennifer Arthur Ataam, Connor Amelung, Lakshmi Santhanam, Ioannis Karakikes, Sharon Gerecht   +10 more
wiley   +1 more source

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women

, 2010
Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sun Ha Jee, Sat Byul Park
core  

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Intensive Medical Care and Cardiovascular Disease Disability Reductions [PDF]

There is little empirical evidence to explain why disability declined among the elderly over the past 20 years. In this paper, we explore the role of improved medical care for cardiovascular disease on health status improvements over time.
Kate A. Stewart, David M. Cutler, Mary Beth Landrum   +2 more
core