Results 121 to 130 of about 797,541 (308)

Cardiovascular and Other Competing Causes of Death in Male Breast Cancer Patients: A Population-Based Epidemiologic Study

Clinical Interventions in Aging, 2021
Hanbin Zhang,1 Wenrui Lin,2 Dongting Chen,1 Kenie Wang,3 Wei Tu,4 Huiwen Lin,4 Kun Li,4 Shangzhu Ye,5 Tianwang Guan,6 Yuerong Chen4 1Department of Clinical Medicine, The Second Clinical College of Guangzhou Medical University, Guangzhou, People’s ...
Zhang H, Lin W, Chen D, Wang K, Tu W, Lin H, Li K, Ye S, Guan T, Chen Y   +9 more
doaj  

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Death and cardiovascular events after bacteriuria among adult women with chronic kidney disease

, 2012
Susmitha Dhanyamraju,1 Michael A Foltzer,2 Xiaoqin Tang,3 H Lester Kirchner,4 Robert M Perkins5,61Department of Nephrology, 2Department of Infectious Diseases, Geisinger Medical Center, Danville, PA, USA; 3Center for Health Research, Danville, PA, USA ...
Dhanyamraju S, Perkins RM, Foltzer MA, Kirchner HL, Tang X   +4 more
core  

Competing risk nomogram for predicting cancer-specific survival in patients with primary bone diffuse large B-cell lymphoma: a SEER-based retrospective study

Frontiers in Medicine
BackgroundCardiovascular death (CVD) represents a significant determinant affecting the long-term survival outcomes of cancer patients, independent of primary tumor effects.
Rongbin Shen, Sichun Xiang, Jianyou Gu, Yu Zhang, Lili Qian, Jianping Shen, Qing Guo, Shana Chen, Chenyang Ma, Jingjing Xiang   +9 more
doaj   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Coffee consumption and coronary calcification: The Rotterdam coronary calcification study

, 2008
BACKGROUND - The role of coffee in the cardiovascular system is not yet clear. We examined the relation of coffee intake with coronary calcification in a population-based cohort.
Hofman, A. (Albert), Witteman, JCM, Matthijs Oudkerk, Vliegenthart, R. (Rozemarijn), Hofman, Albert, Albert Hofman, Hofman, Bert, Oudkerk, M. (Matthijs), Geertruida J. van Woudenbergh, van Rooij, FJA; id_orcid, Geleijnse, J.M., Vliegenthart, R (Rozemarijn), Geleijnse, J.M. (Marianne), Rooij, F.J.A. (Frank) van, Vliegenthart, R., Rozemarijn Vliegenthart, Jacqueline C.M. Witteman, Rooij, F.J.A., van, Geleijnse, Johanna M., Witteman, J.C.M. (Jacqueline), van Rooij, Frank J. A., Geleijnse, JM (Marianne), Witteman, J.C.M., Oudkerk, Matthijs; id_orcid, Johanna M. Geleijnse, Hofman, A., van Woudenbergh, Geertruida J., van Woudenbergh, G.J., Woudenbergh, G.J., van, Woudenbergh, G.J. (Geertruida) van, van Rooij, F.J.A., van Woudenbergh, GJ, Oudkerk, Matthijs, Witteman, Jacqueline C. M., Vliegenthart, Rozemarijn, Oudkerk, M., Frank J.A. van Rooij, Oudkerk, M   +37 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

In Vivo Microplastic Detection With Photoacoustic Imaging

Advanced Science, EarlyView.
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear, Olumide Ogunlade, Jayvian Mavi, Emily J. Deniszczyc, Daolong Chen, Heeva Javaheri, Paul Beard, Mark F. Lythgoe, Daniel J. Stuckey, P. Stephen Patrick   +9 more
wiley   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source