Results 11 to 20 of about 3,668,940 (297)

Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data. [PDF]

, 2011
To describe the likely extent of confounding in evaluating the risks of cardiovascular (CV) events and mortality in patients using diabetes medication. The General Practice Research Database was used to identify inception cohorts of insulin and different
Van Staa, Tjeerd; id_orcid, Leufkens Hubert G. M., Leufkens, Hubert G M, van Staa Tjeerd P., Hubert G M Leufkens, Gallagher, Arlene M, Leufkens, Hubert GM, Smeeth Liam, Suzie Seabroke, Tjeerd P van Staa, Liam Smeeth, Seabroke Suzie, Smeeth, Liam, Arlene M Gallagher, Seabroke, Suzie, Arlene M. Gallagher, Gallagher Arlene M., van Staa, Tjeerd P, Hubert G. M. Leufkens, Tjeerd P. van Staa   +19 more
core   +6 more sources

Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis

Cells, 2020
The vitamin K-dependent factors protein S (PROS1) and growth-arrest-specific gene 6 (GAS6) and their tyrosine kinase receptors TYRO3, AXL, and MERTK, the TAM subfamily of receptor tyrosine kinases (RTK), are key regulators of inflammation and vascular ...
Anna Tutusaus, Montserrat Marí, José T. Ortiz-Pérez, Gerry A. F. Nicolaes, Albert Morales, Pablo García de Frutos   +5 more
doaj   +1 more source

Proteomic and phosphoproteomic analyses of myectomy tissue reveals difference between sarcomeric and genotype-negative hypertrophic cardiomyopathy

Scientific Reports, 2023
Hypertrophic cardiomyopathy (HCM) is a genetically heterogenous condition with about half of cases remaining genetically elusive or non-genetic in origin.
Ramin Garmany, J. Martijn Bos, Surendra Dasari, Kenneth L. Johnson, David J. Tester, John R. Giudicessi, Cristobal dos Remedios, Joseph J. Maleszewski, Steve R. Ommen, Joseph A. Dearani, Michael J. Ackerman   +10 more
doaj   +1 more source

Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome

Biomedicines, 2021
Background: Growth arrest-specific factor 6 (GAS6) and the Tyro3, AXL, and MERTK (TAM) receptors counterbalance pro-inflammatory responses. AXL is a candidate receptor for SARS-CoV-2, particularly in the respiratory system, and the GAS6/AXL axis is ...
Albert Morales, Silvia Rojo Rello, Helena Cristóbal, Aida Fiz-López, Elisa Arribas, Montserrat Marí, Anna Tutusaus, Paloma de la Cal-Sabater, Gerry A.F. Nicolaes, José T. Ortiz-Pérez, David Bernardo, Pablo García de Frutos   +11 more
doaj   +1 more source

Risk of Cardiovascular Death in Osteosarcoma

Journal of the College of Physicians and Surgeons Pakistan, 2023
To assess the risk of cardiovascular mortality (CVM) in patients with osteosarcoma.Descriptive study. Place and Duration of the Study: Department of Orthopaedics, The People's Hospital of Baoan, Shenzhen, Guangdong, China, from 1st January 2019 to 1st January 2022.Data on patients diagnosed with osteosarcoma, between 1975 and 2019, were obtained from ...
Yukun, Jia, Yu, Xiong, Zhan, Peng, Guangye, Wang   +3 more
openaire   +2 more sources

Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis

Stem Cells International, 2022
Hypoxia preconditioning enhances the paracrine abilities of mesenchymal stem cells (MSCs) for vascular regeneration and tissue healing. Implantation of hypoxia-induced mesenchymal stem cells (hi-MSCs) may further improve limb perfusion in a murine model ...
Farina Mohamad Yusoff, Ayumu Nakashima, Ki-ichiro Kawano, Masato Kajikawa, Shinji Kishimoto, Tatsuya Maruhashi, Naoki Ishiuchi, S. Fadilah S. Abdul Wahid, Yukihito Higashi   +8 more
doaj   +1 more source

Sex differences in long QT syndrome

Frontiers in Cardiovascular Medicine, 2023
Long QT Syndrome (LQTS) is a rare, inherited channelopathy characterized by cardiac repolarization dysfunction, leading to a prolonged rate-corrected QT interval in patients who are at risk for malignant ventricular tachyarrhythmias, syncope, and even ...
Nuria Díez-Escuté, Elena Arbelo, Elena Arbelo, Elena Arbelo, Elena Arbelo, Estefanía Martínez-Barrios, Patricia Cerralbo, Sergi Cesar, José Cruzalegui, Freddy Chipa, Victoria Fiol, Irene Zschaeck, Clara Hernández, Oscar Campuzano, Oscar Campuzano, Oscar Campuzano, Georgia Sarquella-Brugada, Georgia Sarquella-Brugada, Georgia Sarquella-Brugada   +18 more
doaj   +1 more source

Clinical course of patients with hypertrophic cardiomyopathy away from tertiary referral care

ESC Heart Failure, 2023
Aims Data on the clinical course of hypertrophic cardiomyopathy (HCM) are mainly derived from tertiary HCM centre studies, and knowledge of clinical outcomes of patients leaving specialty care and returning to local physicians is limited due to gaps ...
Ramin Garmany, J. Martijn Bos, Steve R. Ommen, Michael J. Ackerman, Jeffrey B. Geske   +4 more
doaj   +1 more source

Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study

Heart and Mind, 2023
Background: Chronic medical diseases and recurrent mental disorders are common and may lead to a negative prognosis in adults with cardiovascular diseases (CVDs).
Gerard Ngueta, Claudia Blais, Guillaume Foldes-Busque, Denis Hamel, Paul Poirier   +4 more
doaj   +1 more source

Diabetes type 2: conventional, social and some genetic predictors of cardiovascular death

Атеросклероз, 2021
Aim of the study was to investigate the associations of metabolic, behavioral, socio-economic risk factors and some molecular genetic markers with the risk of cardiovascular death (CVD) in persons with type 2 diabetes (T2DM) aged 45–69 years ...
O. D. Rymar, L. V. Shcherbakova, A. O. Shchetinina, S. V. Mustafina, G. I. Simonova, Yu. S. Bakhareva, E. M. Avdeeva, O. V. Sazonova, V. N. Maksimov, S. K. Malyutina   +9 more
doaj   +1 more source