Results 21 to 30 of about 797,541 (308)

Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data. [PDF]

open access: yes, 2011
To describe the likely extent of confounding in evaluating the risks of cardiovascular (CV) events and mortality in patients using diabetes medication. The General Practice Research Database was used to identify inception cohorts of insulin and different
Van Staa, Tjeerd; id_orcid   +19 more
core   +1 more source

Cell death in the cardiovascular system [PDF]

open access: yesHeart, 2006
Cell death is important for both development and tissue homeostasis in the adult. As such, it is tightly controlled and deregulation is associated with diverse pathologies; for example, regulated cell death is involved in vessel remodelling during development or following injury, but deregulated death is implicated in pathologies such as ...
Murray, Clarke   +2 more
openaire   +2 more sources

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies [PDF]

open access: yes, 2011
BACKGROUND: Guidelines differ about the value of assessment of adiposity measures for cardiovascular disease risk prediction when information is available for other risk factors. We studied the separate and combined associations of body-mass index (BMI),
Nordestgaard, Borge G.   +75 more
core   +1 more source

Entosis: The emerging face of non-cell-autonomous type IV programmed death

open access: yesBiomedical Journal, 2017
The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological ...
Isabelle Martins   +10 more
doaj   +1 more source

Rosiglitazone evaluated for cardiovascular outcomes - An interim analysis [PDF]

open access: yes, 2007
BACKGROUND: A recent meta-analysis raised concern regarding an increased risk of myocardial infarction and death from cardiovascular causes associated with rosiglitazone treatment of type 2 diabetes. METHODS: We conducted an unplanned interim analysis of
McMurray, JJV   +19 more
core   +1 more source

Cell Death in Cardiovascular Disease [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2011
Cell death has been recognized in the cardiovascular system for centuries. In Virchow's 1858 lectures, he described atherosclerosis as producing new tissue, followed by cell death: “Thus, we have here an active process which really produces new tissues, but then hurries on to destruction in consequence of its own development.”1 Degraded and dying cells
openaire   +2 more sources

C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction [PDF]

open access: yes, 2012
BACKGROUND: There is debate about the value of assessing levels of C-reactive protein (CRP) and other biomarkers of inflammation for the prediction of first cardiovascular events.
Iso, Hiroyasu   +438 more
core   +1 more source

Osteoarthritis and cardiovascular death [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2003
Haara et al recently published a study assessing epidemiological aspects of osteoarthritis (OA) in Finland.1 A finding of interest was their identification of OA (in any finger joint) as a predictor of cardiovascular death among men, with the authors suggesting an undetermined metabolic factor as a mechanism. It may be that the …
K A Grindulis   +5 more
openaire   +1 more source

Effect of Salt Substitution on Cardiovascular Events and Death [PDF]

open access: yesNew England Journal of Medicine, 2021
Salt substitutes with reduced sodium levels and increased potassium levels have been shown to lower blood pressure, but their effects on cardiovascular and safety outcomes are uncertain.We conducted an open-label, cluster-randomized trial involving persons from 600 villages in rural China.
Neal, B   +32 more
openaire   +5 more sources

Gut Microbiota‐Dependent Trimethylamine N‐oxide and Cardiovascular Outcomes in Patients With Prior Myocardial Infarction: A Nested Case Control Study From the PEGASUS‐TIMI 54 Trial

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Trimethylamine N‐oxide (TMAO) may have prothrombotic properties. We examined the association of TMAO quartiles with major adverse cardiovascular events (MACE) and the effect of TMAO on the efficacy of ticagrelor.
Baris Gencer   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy