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Artificial Gravity as a Countermeasure to the Cardiovascular Deconditioning of Spaceflight: Gender Perspectives [PDF]
Space flight-induced physiological deconditioning resulting from decreased gravitational input, decreased plasma volume, and disruption of regulatory mechanisms is a significant problem in returning astronauts as well as in normal aging.
Joyce M. Evans +2 more
doaj +7 more sources
High-Intensity Exercise Mitigates Cardiovascular Deconditioning During Long-Duration Bed Rest [PDF]
Head-down-tilt bed rest (HDT) mimics the changes in hemodynamics and autonomic cardiovascular control induced by weightlessness. However, the time course and reciprocal interplay of these adaptations, and the effective exercise protocol as a ...
Martina A. Maggioni +14 more
doaj +6 more sources
Cardiovascular deconditioning and impact of artificial gravity during 60-day head-down bed rest—Insights from 4D flow cardiac MRI [PDF]
Microgravity has deleterious effects on the cardiovascular system. We evaluated some parameters of blood flow and vascular stiffness during 60 days of simulated microgravity in head-down tilt (HDT) bed rest.
Jeremy Rabineau +9 more
doaj +2 more sources
Multi-System Deconditioning in 3-Day Dry Immersion without Daily Raise
Dry immersion (DI) is a Russian-developed, ground-based model to study the physiological effects of microgravity. It accurately reproduces environmental conditions of weightlessness, such as enhanced physical inactivity, suppression of hydrostatic ...
Steven De Abreu +11 more
doaj +3 more sources
A cardiovascular-motor axis framework for perfusion-mediated motor impairment [PDF]
Cardiovascular disease is the leading cause of death worldwide, and among survivors of heart failure, peripheral arterial disease, valvular disease, and atrial fibrillation many develop motor impairment: weakness, slow gait, sarcopenia, frailty.
Matteo Scorcelletti +5 more
doaj +2 more sources
Physical activity, mobility or patterned mobility (i.e., exercise) is intrinsic to the functioning of Homo sapiens, and required for maintenance of health.
David A. Hart +3 more
doaj +1 more source
Significant progress has been made in the development of countermeasures to attenuate the negative consequences of prolonged exposure to microgravity on astronauts’ bodies.
Eric T. Hedge +9 more
doaj +1 more source
Astronauts in microgravity experience multi-system deconditioning, impacting their inflight efficiency and inducing dysfunctions upon return to Earth gravity. To fill the sex gap of knowledge in the health impact of spaceflights, we simulate microgravity
Adrien Robin +28 more
doaj +1 more source
Patients with neurological impairments often experience physical deconditioning, resulting in reduced fitness and health. Powered exoskeleton training may be a successful method to combat physical deconditioning and its comorbidities, providing patients ...
Damien Duddy +5 more
doaj +1 more source
The application of artificial gravity in medicine and space
Gravity plays a crucial role in physiology. The lack of gravity, like in long duration spaceflight missions, cause pathologies in e.g., the musculoskeletal system, cardiovascular deconditioning, immune system deprivation or brain abnormalities, to just ...
Eugenia Isasi +4 more
doaj +1 more source

