Results 21 to 30 of about 2,636,084 (314)

Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway

Frontiers in Physiology, 2018
Background: Lysophosphatidic acid (LPA), as a phospholipid signal molecule, participates in the regulation of various biological functions. Our previous study demonstrated that LPA induces cardiomyocyte hypertrophy in vitro; however, the functional role ...
Jinjing Yang, Jinjing Yang, Jinjing Yang, Jiyao Xu, Jiyao Xu, Xuebin Han, Xuebin Han, Hao Wang, Yuean Zhang, Yuean Zhang, Jin Dong, Jin Dong, Yongzhi Deng, Yongzhi Deng, Jingping Wang, Jingping Wang   +15 more
doaj   +1 more source

The genetics of cardiovascular disease [PDF]

, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero, Aitman, Anna F. Dominiczak, Benhamou, Bhatnagar, Bowcock, Caulfield, Chen, Christian Delles, Clark, Conrad, Cowley, Cupples, Delles, Delles, Delles, Dominiczak, Dominiczak, Dutil, Edwards, Emilsson, Garrett, Good, Graham, Grunfeld, Gunderson, Guzik, Hamilton, Hamilton, Harrap, Hunt, Iwai, Jakubowska, Jeffs, Jeffs, Ji, Kathiresan, Kerr, Klein, Latronico, Levy, Martin W. McBride, Matarín, Matarín, Matsuzaki, McBride, McBride, McCarthy, Monti, Moreno, Mueller, Newhouse, Oniki, Padmanabhan, Padmanabhan, Petretto, Pollex, Rapp, Roodi, Samani, Sandhu, Sandosh Padmanabhan, Sayed-Tabatabaei, Sharma, Staessen, Teo, Tobin, Tobin, Turner, Wallace, Wilson, Zalba, Zimmerli   +72 more
core   +1 more source

Who Has Seen Patients With ST‐Segment–Elevation Myocardial Infarction? First Results From Italian Real‐World Coronavirus Disease 2019

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background After the coronavirus disease 2019 outbreak, social isolation measures were introduced to contain infection. Although there is currently a slowing down of the infection, a reduction of hospitalizations, especially for myocardial infarction ...
Valeria Cammalleri, Saverio Muscoli, Daniela Benedetto, Giuseppe Stifano, Massimiliano Macrini, Alessio Di Landro, Marco Di Luozzo, Massimo Marchei, Enrica Giuliana Mariano, Linda Cota, Domenico Sergi, Andrea Bezzeccheri, Michela Bonanni, Martino Baluci, Pasquale De Vico, Francesco Romeo   +15 more
doaj   +1 more source

Walks4work: Rationale and study design to investigate walking at lunchtime in the workplace setting [PDF]

, 2012
Background: Following recruitment of a private sector company, an 8week lunchtime walking intervention was implemented to examine the effect of the intervention on modifiable cardiovascular disease risk factors, and further to see if walking environment ...
A Alwan, A Puig-Ribera, AJ Hautala, AJ Minisi, AJ Nelson, BJ Park, C Tudor-Locke, CB Chan, CL Craig, CR Cole, CR Cole, D Watson, Daniel K Brown, Department of Health, Department_of_Health, DP Zipes, DR Seals, EK Nisbet, EM Murtagh, EO Nishime, G Borg, GE Billman, GE Duncan, GJ Welk, GR Sandercock, H Hemingway, H Tsuji, HE Brown, I Hess, J Barton, J Barton, J Pretty, J Pretty, J Pretty, J Stevens, Jo L Barton, JP Buckley, Jules Pretty, K Sykes, KY Chen, LW Rystedt, M Rosenberg, MH Murphy, MS Penn, MT La Rovere, MT La Rovere, N Gilson, NA King, Q Li, R Rosmond, RP Juster, RW Hoyt, S Cohen, S Ogoh, SB Racette, SN Blair, T Chandola, T Cox, T Hartig, Task Force, Valerie F Gladwell, VF Gladwell, VS Conn, WB Schaufeli, WB Schaufeli, WHO, WHO, WHO, WL Haskell, X Jouven   +69 more
core   +2 more sources

Salt intake, stroke, and cardiovascular disease : meta-analysis of prospective studies [PDF]

, 2009
Objective: To assess the relation between the level of habitual salt intake and stroke or total cardiovascular disease outcome. Design: Systematic review and meta-analysis of prospective studies published 1966-2008.
Strazzullo, Pasquale, Elia, Lanfranco d', Kandala, Ngianga-Bakwin, Cappuccio, Francesco   +3 more
core   +1 more source

Ochronotic cardiovascular disease [PDF]

Clinical Cardiology, 1985
AbstractOchronosis is a disease of tyrosine metabolism. Although most commonly associated with alcaptonuria and spondyloarthropathy, cardiovascular abnormalities have been associated. We describe a case which exemplifies the cardiovascular findings in this entity.
M, Ptacin, J, Sebastian, V S, Bamrah
openaire   +2 more sources

Associations of epicardial fat thickness and circulating markers of myocardial fibrosis in patients with myocardial infarction

Атеросклероз, 2020
Aim: to determine the association of the thickness of epicardial adipose tissue (EAT) with the level of biological markers and the degree of myocardial fibrosis one year after myocardial infarction (MI) in patients with visceral obesity (VO ...
E. V. Belik, O. V. Gruzdeva, Yu. A. Dileva, D. A. Borodkina, N. K. Brel, E. E. Bychkova, T. B. Pecherina, V. N. Karetnikova, V. V. Kashtalap, E. I. Palicheva, A. A. Kuzmina, E. V. Fanaskova, O. L. Barbarash   +12 more
doaj   +1 more source

High neutrophil to lymphocyte ratio with type 2 diabetes mellitus predicts poor prognosis in patients undergoing percutaneous coronary intervention: a large-scale cohort study

Cardiovascular Diabetology, 2022
Background Inflammation plays a crucial role in the pathogenesis and progression of coronary artery disease (CAD). The neutrophil to lymphocyte ratio (NLR) is a novel inflammatory biomarker and its association with clinical outcomes in CAD patients with ...
Jining He, Xiaohui Bian, Chenxi Song, Rui Zhang, Sheng Yuan, Dong Yin, Kefei Dou   +6 more
doaj   +1 more source

Risk Factors for Long-Term Coronary Artery Calcium Progression in the Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2015
BackgroundCoronary artery calcium (CAC) detected by noncontrast cardiac computed tomography scanning is a measure of coronary atherosclerosis burden. Increasing CAC levels have been strongly associated with increased coronary events.
Blaha, Michael J, Budoff, Matthew, Gassett, Amanda J, Kaufman, Joel D, Kronmal, Richard, McClelland, Robyn L, Olives, Casey, Sheppard, Lianne   +7 more
core   +2 more sources

High triglyceride-glucose index predicts cardiovascular events in patients with coronary bifurcation lesions: a large-scale cohort study

Cardiovascular Diabetology, 2023
Background Coronary bifurcation lesion, as a complex coronary lesion, is associated with higher risk of long-term poor prognosis than non-bifurcation lesions.
Jining He, Sheng Yuan, Chenxi Song, Yanjun Song, Xiaohui Bian, Guofeng Gao, Kefei Dou   +6 more
doaj   +1 more source