Results 61 to 70 of about 6,863,547 (308)

Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan [PDF]

, 2014
Katsuya Onishi,1 Daisuke Yoshimoto,2 Gerry W Hagan,3 Paul W Jones4 1Onishi Heart Clinic, Mie, 2Medical Affairs Respiratory, GlaxoSmithKline KK, Tokyo, Japan; 3Independent Consultant, Marbella, Spain; 4Division of Clinical Science, St George's ...
Jones PW, Hagan, GW, Hagan GW, Onishi, K, Jones, PW, Onishi K, Yoshimoto D, Yoshimoto, D   +7 more
core   +1 more source

Cardiovascular disease and all-cause mortality associated with individual and combined cardiometabolic risk factors

BMC Public Health, 2023
Background Previous studies have investigated the association between cardiometabolic risk factors and cardiovascular disease (CVD), but evidence of the attributable burden of individual and combined cardiometabolic risk factors for CVD and mortality is ...
Xue Cao, Linfeng Zhang, Xin Wang, Zuo Chen, Congyi Zheng, Lu Chen, Haoqi Zhou, Jiayin Cai, Zhen Hu, Yixin Tian, Runqing Gu, Yilin Huang, Zengwu Wang   +12 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Workplace-based primary prevention intervention reduces incidence of hypertension: a post hoc analysis of cluster randomized controlled study

BMC Medicine, 2023
Background A workplace-based primary prevention intervention be an effective approach to reducing the incidence of hypertension (HTN). However, few studies to date have addressed the effect among the Chinese working population.
Zhen Hu, Xin Wang, Conglin Hong, Congyi Zheng, Linfeng Zhang, Zuo Chen, Haoqi Zhou, Yixin Tian, Xue Cao, Jiayin Cai, Runqing Gu, Ye Tian, Lan Shao, Zengwu Wang   +13 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women [PDF]

, 2010
Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sun Ha Jee, Sat Byul Park
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Screening families of patients with premature coronary heart disease to identify avoidable cardiovascular risk: a cross-sectional study of family members and a general population comparison group [PDF]

, 2010
<b>Background:</b> Primary prevention should be targeted at individuals with high global cardiovascular risk, but research is lacking on how best to identify such individuals in the general population.
Pell, A.C.H., Thompson, H.J., Helen J Thompson, Clara K Chow, Anderson, J., Pell, J., Alastair CH Pell, Chow, C.K., Jill P Pell, Pell Jill P, Anderson Judith, Pell Alastair CH, Chow Clara K, Judith Anderson, Thompson Helen J   +14 more
core   +1 more source

COPD and Cardiovascular Disease

Pulmonology, 2019
COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020. COPD and cardiac comorbidities are frequently associated.
André, S., Conde, B., Fragoso, E., Boléo-Tomé, J.P., Areias, Vanda, Cardoso, J.   +5 more
openaire   +6 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source