Results 21 to 30 of about 1,188,706 (294)

Efficacy, usage and adverse effects of furosemide in cardiovascular diseases

Journal of Medical and Scientific Research
Cardiovascular diseases can be caused by numerous beginning conditions. The underpinning causes may include heart/ myocardial inflammation, cardio myopathy, coronary vascular complaint (CAD), dyslipidemia, hypertension, pulmonary hypertension, and ...
Reddy AU, Poornender AR
doaj   +1 more source

Hyperuricemia and Cardiovascular Disease

Reviews in Cardiovascular Medicine, 2017
Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research.
Ruochi Zhao, Fuxing Zhang, Dandan Zhang, Wenyuan Zheng, Jinsong Cheng, Zhenyu Xu, Shuangshuang Zhang, Ning Huangfu, Yong Wang   +8 more
openaire   +5 more sources

Cancer and Cardiovascular Disease [PDF]

Cardiology Research and Practice, 2011
Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially over the next generation. Advancement in cancer therapy and supportive care
Syed Wamique Yusuf, Carlo Cipolla, Jean-Bernard Durand, Daniel J. Lenihan   +3 more
openaire   +3 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Results of preclinical trials in a sheep model of biodegradable small-diameter vascular grafts

Вестник трансплантологии и искусственных органов, 2022
Surface modification of polymer vascular matrices is a promising development for preventing vascular graft thrombosis, improving long-term patency and accelerating remodeling. Objective: to study the outcomes of long-term patency of PHBV/PCL/GFmix grafts
L. V. Antonova, E. O. Krivkina, M. Yu. Khanova, E. A. Velikanova, V. G. Matveeva, А. V. Mironov, A. R. Shabaev, Е. A. Senokosova, T. V. Glushkova, M. Yu. Sinitsky, R. А. Mukhamadiyarov, L. S. Barbarash   +11 more
doaj   +1 more source

Menopause and cardiovascular disease [PDF]

Journal of Mid-life Health, 2019
Menopausal health demand priority in Indian scenario due to increase in life expectancy and growing population of menopausal women. Time demands to promote a multidisciplinary, multi-factorial, comprehensive approach to the care of these women. By the medium of this editorial and our experience in dealing women in advancing age in and around menopause,
Ranu Patni, Annil Mahajan, Varun Gupta
openaire   +3 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Experience in the development of a system for repeated prosthetic heart valves

Сибирский научный медицинский журнал, 2023
The failure of heart valve bioprostheses, requiring repeated intervention to replace them, is a serious drawback that narrows the scope of such devices.
E. A. Ovcharenko, K. Yu. Klyshnikov, A. N. Stasev, A. V. Evtushenko, I. K. Khalivopulo, D. V. Borisenko, T. V. Glushkova, A. V. Ivanova, I. V. Dvadtsatov, S. S. Krutitsky, Yu. A. Kudryavtseva, O. L. Barbarash, L. S. Barbarash   +12 more
doaj   +1 more source

Testosterone and Cardiovascular Disease [PDF]

The Open Cardiovascular Medicine Journal, 2016
Cardiovascular disease [CVD] is a leading cause of mortality accounting for a global incidence of over 31%. Atherosclerosis is the primary pathophysiology underpinning most types of CVD. Historically, modifiable and non-modifiable risk factors were suggested to precipitate CVD.
Tambo, Amos, Roshan, Mohsin H.K., Pace, Nikolai Paul   +2 more
openaire   +4 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source