Results 41 to 50 of about 1,500,985 (317)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2007 Breckenkamp J, Mielck A, Razum O. Health inequalities in Germany: do regional-level variables explain differentials in cardiovascular risk? BMC Public Health.
Breckenkamp, Jürgen +8 more
core +2 more sources
Association between Life’s Essential 8 and depression: a population-based study
Archives of Medical ScienceIntroduction Previous research has established a connection between depression and an elevated risk of cardiovascular disease. In this study, we sought to examine the association between Life’s Essential 8 (LE8), an updated metric for assessing ...
Haiying Jin +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Health care expenditure on cardiovascular diseases 2008-09 [PDF]
, 2014 Summary: Health-care expenditure for cardiovascular disease (CVD) is higher than for any other disease group and the impact of CVD on the health of Australians is considerable.
core
Food for Thought: Nourishing Cardiovascular Health Amidst the Exposome
Methodist DeBakey Cardiovascular JournalThe cumulative exposures of an individual during their lifetime, known as the exposome, encompass environmental exposures and lifestyle factors that significantly impact cardiovascular health.
Bassel Daher
doaj +1 more source
Annals of Medicine, 1989 This paper - in tribute to Martti Karvonen not only as researcher, teacher, organizer, friend, but also as statesman and strategist - focusses on several major contemporary strategic issues central for advancing cardiovascular health. These include: 1.
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Intersectionality and Social Drivers of Health in Cardiovascular Care
Methodist DeBakey Cardiovascular JournalSocial drivers of health (SDOH) are a significant contributor to persistent cardiovascular health disparities in the United States and globally. SDOH include psychosocial, environmental, socioeconomic, cultural, and governmental factors that impact ...
Madelyn Hurwitz +3 more
doaj +1 more source
Frontiers in Physiology, 2020 The following narrative review addresses the relationship between physical activity and exercise with cardiovascular health, focusing primarily on the following risk factors for atherosclerosis: hypertension, dyslipidemia, and vascular function ...
Lucas P. Santos +5 more
doaj +1 more source